The cognitive and functional deterioration that is observed in many "poor-outcome" patients with schizophrenia suggests a neurodegenerative process extending into late life. Previous diagnostic studies have excluded known diseases as explanations for this dementia. However, we hypothesized relatively small accumulations of age- or disease-related lesions occurring an otherwise abnormal brain could result schizophrenia.Postmortem were conducted using 23 prospectively accrued elderly persons...

ABSTRACT Complete esophageal obstruction is a major side effect of radiotherapy for head and neck cancers. We present 65-year-old man with complete due to chemoradiotherapy 7 years gastric tube dependence. A combined anterograde retrograde endoscopic procedure was successfully performed using direct transillumination from the scope visualize excise obstructing mucosa, without fluoroscopic guidance. The patient tolerated well, no complications on follow-up. This fluoroscopy-free rendezvous...

The neutrophil–lymphocyte ratio (NLR), as a marker of inflammation, is associated with the severity peripheral artery disease (PAD). role NLR on predicting future complications after elective revascularization for patients PAD remains unknown. We aimed to examine in development major adverse limb events (MALE) and long-term mortality these patients. evaluated 1708 procedures from May 2001 December 2015 at Veterans Affairs Western New York Healthcare System prospectively maintained vascular...

Medication-induced esophagitis is a well-known but relatively rare clinical diagnosis, most common in patients with preexisting esophageal dysmotility, obstruction, or altered anatomy. Esophagitis dissecans superficialis (EDS) endoscopic finding characterized by sloughing of large fragments the mucosal lining. The causes EDS include prior trauma, heavy smoking history, ingestion alcoholic and hot beverages, immunosuppression. We present unique case secondary to ferrous sulfate-induced pill...

In this paper we introduce The Interactive Sensory Program for Affective Learning (InSPAL) a pioneering virtual learning programme designed the severely intellectually disabled (SID) students, who are having cognitive deficiencies and other sensory-motor handicaps, thus need more help attention in overcoming their difficulties. Through combining integrating interactive media reality technology with principles of art therapy relevant pedagogical techniques, InSPAL aims to strengthen SID...

Direct-acting antiviral (DAA) therapy is often well-tolerated, and adverse events from DAA are uncommon. We report a case of woman who underwent orthotopic liver transplant for chronic hepatitis C infection later developed alloimmune shortly after starting recurrent infection. The patient acute approximately 2 weeks treatment with sofosbuvir, velpatasvir, voxilaprevir. This proposes dysregulation immune surveillance due to the stimulation host immunity rapid elimination viral load as...

Cannabinoid receptors are potential therapeutic targets in a variety of gastrointestinal tract disorders. The authors hypothesize that the use cannabis is associated with better control symptoms irritable bowel syndrome (IBS). This study aimed to examine utilization inpatient services by patients IBS who did and not report cannabis.This retrospective cohort utilized 2016 Nationwide Readmissions Database. Inclusion criteria included principal diagnosis IBS. primary outcome was 30-day hospital...

Epstein-Barr virus (EBV) is a member of the herpes family and affects people worldwide. EBV-infected colitis can occur in patients immunocompromised states. However, EBV-induced immunocompetent extremely rare. A 34-year-old man with prior history possible intussusception, who underwent right hemicolectomy, presented abdominal pain rectal bleeding. Laboratory investigations were unremarkable, patient colonoscopy, which showed colitis. Both infectious inflammatory bowel disease (IBD) workups...

Objectives This study explores the characteristics and outcomes, including inpatient mortality, length of stay, pancreatitis complications in patients hospitalized with acute (AP) coexisting systemic lupus erythematosus (SLE). Methods Patients AP from National Inpatient Sample 2014 were selected. Patient outcomes compared between groups without SLE. Age, sex, race, Elixhauser Comorbidity Index (ECI), etiologies measured. The interest complications, respiratory failure, renal myocardial...

ABSTRACT Colorectal anastomotic strictures are a well-known complication of low anterior resection. Depending on their location, amendable to different forms endoscopic intervention. However, all interventions contingent passing guidewire across the stricture. We present case patient with complete stricture that could not be traversed by conventional endoscopy and unique method which lumen was created in allowed for passed across.

Background Recent studies have revealed the endocannabinoid system as a potential therapeutic target in management of nonalcoholic fatty liver disease (NAFLD). Cannabis use is associated with reduced risk for NAFLD, we hypothesized that cannabis would be less liver-related clinical complications patients NAFLD. Aim To assess effects on outcomes hospitalized Methods We performed retrospective matched cohort study based querying 2014 National Inpatient Sample (NIS) hospitalizations adults...

The impact of the COVID-19 pandemic on palliative care intervention (PCIs) in patients with do-not-resuscitate (DNR) status remains uncertain.Case-control study DNR order RT-PCR confirmed SARS-COV2 infection (cases), and those but without (controls). primary outcome measures included timing delivery PCIs, secondary pre-admission characteristics in-hospital death.The ethnicity distribution was comparable between 69 cases 138 controls, including Black/African Americans (61% vs. 44%),...

Physicians need to recognize the potential complications of endoscopic retrograde cholangiopancreatography (ERCP), which are rare but can be serious. We describe a case post-ERCP subcapsular hepatic hematoma (SHH). A 39-year-old man with history alcohol use, complicated by chronic pancreatitis and common bile duct (CBD) stricture, presented right upper quadrant pain two weeks after placement stent for CBD stricture. He was managed control antibiotics. SHH is complication ERCP. Hematomas...

Objectives Acute diverticulitis is a common gastrointestinal illness due to diverticular inflammation and focal necrosis. Diabetes mellitus has been reported influence the outcomes of patients with disease. Our study aimed examine inpatient complications acute coexisting diabetes mellitus. Methods The Nationwide Inpatient Sample was used identify adult in 2014 admitted for diverticulitis. Primary were mortality, length stay (LOS), total hospitalization charges. Secondary interventions....

Non-alcoholic fatty liver disease (NAFLD) is prevalent in almost 25% of the Western population and predicted to become one leading causes end-stage disease. There increasing evidence that NAFLD a risk factor for cardiovascular disease, specifically coronary artery via disruption metabolism glucose lipids body, state systemic inflammation promotes atherosclerosis. This study aims explore outcomes patients who underwent percutaneous intervention (PCI) with or without placement drug-eluting...

INTRODUCTION: Proinflammatory markers such as interleukin (IL)-6 have been closely associated with various pathological processes, oxidative stress, apoptosis, and fibrosis that promote formation of atrial fibrillation (AF). These are characteristically elevated in inflammatory bowel disease (IBD). It has shown AF a higher prevalence IBD. is important to analyze the effect comorbid IBD on hospital length stay mortality. METHODS: The National Inpatient Sample (NIS) database, representing...

INTRODUCTION: Cases of autoimmune hepatitis induced after Direct-acting antiviral (DAA) in patients undergoing treatment for C virus (HCV) infection have been reported the literature. This is a case report alloimmune post-liver transplant patient shortly starting DAA recurrent graft. CASE DESCRIPTION/METHODS: A 56-year-old Egyptian woman with history liver cirrhosis secondary to chronic HCV, genotype 4, complicated by hepatocellular carcinoma underwent orthotopic transplant. Two months...

Introduction: Hydrogen peroxide was used for the management of meconium ileum and fecal impaction, it often as a home remedy constipation. Its use has now been abandoned due to harmful effects such hydrogen peroxide-induced colitis, stricture, or perforation an enema. We present case proctitis in young male. Chemical-induced can mimic presentation other conditions ulcerative pseudomembranous ischemic colitis. Therefore, signifies importance obtaining careful, pertinent history make accurate...