Rupali R. M. Sathe

ORCID: 0000-0003-4315-1872
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About
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Research Areas
  • Microbial Metabolic Engineering and Bioproduction
  • Photosynthetic Processes and Mechanisms
  • Microbial Community Ecology and Physiology
  • Sulfur Compounds in Biology
  • Antimicrobial Peptides and Activities
  • Alcoholism and Thiamine Deficiency
  • Antimicrobial agents and applications
  • Eicosanoids and Hypertension Pharmacology
  • Biosensors and Analytical Detection
  • Adenosine and Purinergic Signaling
  • Metabolism and Genetic Disorders

Indian Institute of Science Education and Research Pune
2020-2022

We report a biodegradable fluorescent theranostic nanoprobe design strategy for simultaneous visualization and quantitative determination of antibacterial activity the treatment bacterial infections. Cationic-charged polycaprolactone (PCL) was tailor-made through ring-opening polymerization methodology, it self-assembled into well-defined tiny 5.0 ± 0.1 nm aqueous nanoparticles (NPs) having zeta potential +45 mV. Excellent bactericidal at 10.0 ng/mL concentration accomplished in...

10.1021/acs.biomac.0c00653 article EN Biomacromolecules 2020-06-15

Microbial communities occupy diverse niches in nature, and community members routinely exchange a variety of nutrients among themselves. While large-scale metagenomic metabolomic studies shed some light on these exchanges, the contribution individual species molecular details specific interactions are difficult to track. In this study, we follow vitamin B1 (thiamin) its intermediates between microbes within synthetic cocultures Escherichia coli Vibrio anguillarum. Thiamin contains two...

10.1128/jb.00503-21 article EN Journal of Bacteriology 2022-03-31

Abstract Microbial communities occupy diverse niches in nature, and exchanges of metabolites such as carbon sources, amino acids, vitamins occur routinely among the community members. While large-scale metagenomic metabolomic studies shed some light on these exchanges, contribution individual species molecular details specific interactions are difficult to track. Here, we explore picture vitamin B 1 (thiamin) metabolism occurring synthetic Escherichia coli thiamin auxotrophs which engage...

10.1101/2021.09.29.462401 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-09-29
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