Background Globally, the most prevalent sexually transmitted infection is human papillomavirus, or HPV. The primary difficulty with this his persistence in cervical tissue, which can eventually result cancer after decades. Finding social elements that might encourage HPV's tissue was aim of investigation. Methods This work carried out three regions Cameroon, and covered 1443 women for cytological analyses using Pap test. Positive pap smears were selected to characterize papillomavirus...

Background/Objectives: Obesity is a rising public health concern in Africa, with aggravating effects on several diseases including the recent COVID-19 pandemic. We analyzed epidemiology of bioimpedance analysis-based adipose obesity and evaluated its predictive potential clinical value for SARS-CoV-2 infection. Methods: A one-year cross-section study was conducted at seven referral centers town Douala, Cameroon. Demographic, anthropometric, data were obtained from each participant. Body...

Women infected with human immunodeficiency virus (HIV) may be at higher risk of developing cervical cancer than non women. In a pilot study, we assessed the relationships among cytology abnormalities associated to Human Papillomavirus (HPV), HIV infection and Highly Active Antiretroviral Therapy (HAART) on development Squamous Intraepithelial lesions (SILs). Out 70 women from Douala -Cameroon (Central Africa) that included in half (35) were under HAART. After obtaining information related...

The use of herbal medicines as complements or alternatives to orthodox has been on the increase. There erroneous belief that these are free from adverse effects. Schefflera barteri is popularly used in West region Cameroon for treatment various diseases such diarrhea, spasm, pneumonia and animals bite. Considering ethnopharmacological relevance this plant, study was designed investigate possible toxic effects stem bark extract S. barteri. prepared by maceration dry powder methylene...

The infection of people with haemophilia by human immunodeficiency virus (HIV) through blood transfusions demonstrated the potential risks infectious disease transmission transfusions. microorganisms that can be transmitted transfusion include: hepatitis viruses B, C, D, and G, HIV, cytomegalovirus, T lymphotrophic (HTLV I II), Treponema pallidum, Brucella spp, Toxoplasma gondii, Plasmodium spp trypanosoma cruzi. We estimated prevalence transfusion-transmissible B C viruses, syphilis,...

In this study, five species (Enantia cholorantha Oliv., Pteleopsis hylodendron Mildbr.and Spathodea campanulata P. Beauv., Costus afer Ker-Gawler and Mormodica charantia L.) belonging to families were used for treatment of viral diseases including chicken pox, measles, influenza, shingles and hepatitis. The ethnobotanical survey plant medicine was conducted in the Centre South regions Cameroon. study aim obtain information on use plants diseases, organs used, method preparing herbal...

Pteleopsis hylodendron (Combretaceae) is used in Cameroon and West Africa folk medicine for the treatment of various microbial infections (measles, chickenpox, sexually transmitted diseases). The antibacterial properties methanolic extract fractions from stem bark were tested against three Gram-positive bacteria eight Gram-negative using Agar-well diffusion Broth microdilution methods. Antioxidant activities crude investigated by DPPH radical scavenging activity β-carotene-linoleic acid...

Surveillance of COVID-19/SARS-CoV-2 dynamics is crucial to understanding natural history and providing insights into the population’s exposure risk specific susceptibilities. This study investigated seroprevalence SARS-CoV-2 antibodies, its predictors, immunological status among unvaccinated patients in Cameroon. A multicentre cross-sectional was conducted between January September 2022 town Douala. Patients were consecutively recruited, data interest collected using a questionnaire. Blood...

Les infections du tractus génital femelle représentent un problème de santé publique. Au Cameroun, les données concernant leur épidémiologie sont plus en disponibles mais néanmoins restent obsolètes particulièrement dans la ville Douala. Une étude transversale a été conduite trois hôpitaux Douala le but déterminer prévalence des génitales et facteurs risque associés. Ainsi, 300 femmes ont incluses l’étude. fiche d’enquête utilisée pour collecter informations participantes. Des prélèvements...

To analyze variations in blood profile, the extent of hematological disorders, and impact comorbidities COVID-19 vaccination on profile parameters their clinical value for prognostic SARS-CoV-2 infection.This cross-sectional study took place Douala, Cameroon. A complete count molecular detection were performed patients. Clinical was appraised using area under curve (AUC) analysis.In total, 420 participants included. significant reduction such as lymphocytes (p < 0.0001), red cells (P =...

Objective: Despite its contribution in managing and saving human lives, blood transfusion nonetheless can represent one obvious hazard the transmission of many infectious diseases, among which malaria. This study aimed at determining risk transfusion-transmitted malaria (TTM) from student donors. Methods: A cross-sectional was carried out January 2015 students living town Douala, Cameroon. One hundred seventy nine (179) aged between 18 32 years were included their tested for presence...

Aims: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV-2) still negatively impacting the world. This study aimed at determining prevalence of COVID-19 and comorbidities, associated factors, evaluating impact these comorbidities on patients.&#x0D; Study Design: Cross-sectional hospital-based study.&#x0D; Place Duration Study: From January to March 2022, present was conducted four health facilities in Douala town (Littoral Region, Cameroon).&#x0D;...

Background and Objective: Vaccination is the most cost-effective public health intervention to control diseases such as current COVID-19 pandemic.This study aimed determine prevalence, clinical profile determinants of vaccination uptake SARS-CoV-2 breakthrough infection.Materials Methods: A cross-sectional was conducted in Douala, Cameroon from January, September, 2022.A pretested structured questionnaire used collect sociodemographic, anthropometric data participants during individual...

In cynomolgus monkeys, we compared two human‐derived SIV mac 251 whole virus vaccines, a long vs short immunization schedule, and different challenge viruses. Both vaccines induced protection after with 251/32H. There was no difference between the schedules of immunization. Seven five which were protected following first challenge, reboosted rechallenged monkey‐derived 251, but observed. The titers anti‐human cell or ‐SIV neutralizing antibodies not related to protection.

Breast cancer is a major public health concern throughout the world, particularly in Cameroon. Numerous modalities, including surgery, radiotherapy, and chemotherapy, have been used for clinical therapy. Despite advances anti-cancer therapies, use of these methods to treat often associated with deleterious side effects multi-drug resistance conventional drugs, which has led development new therapeutic methods, peptides (ACP). The aim this study was produce that could be potential modulators...

Background and aimVitamin D deficiency (VDD) is a global public health problem in African populations. This study aimed at determining the prevalence, characteristics, determinants of VDD era SARS-CoV-2/COVID-19. was conducted from January to September 2022 seven facilities Douala, Cameroon.MethodsA structured, pre-tested questionnaire administered each participant collect participants' information. Molecular detection SARS-CoV-2 genome done. A serum level 25-hydroxyvitamin < 20 ng/mL used...

Aims: This study aimed at determining epidemiological, clinical, behavioural and risk factors for breast cancer (BC) among young women living in Cameroon.&#x0D; Study Design: Cross-sectional case-control study.&#x0D; Place Duration of Study: The took place the Oncology departments two reference hospitals Douala (Littoral Region, Cameroon), from July 2020 to 2021.&#x0D; Methodology: An ad hoc questionnaire form was used collect data interest. Anthropometric bioimpedance parameters were...

Objective: Breast cancer in women of childbearing age (WCBA) is a major public health concern. This study aimed to determine variation and determinants lipid profile among Cameroonian WCBA diagnosed with breast cancer. Materials Methods: A case-control took place at two reference hospitals Douala, Cameroon. total 176 (88 cases 88 controls) were finally enrolled. Interviewer-administered questionnaires used collect sociodemographic, behavioural, clinical anthropometric data. Three millilitres...

Abstract Background Surveillance of COVID-19/SARS-CoV-2 dynamics is crucial to understanding natural history and providing insights into the population’s exposure risk specific susceptibilities. This study investigated seroprevalence SARS-CoV-2 antibodies, its predictors, immunological status among unvaccinated patients in Cameroon. Materials Methods A multicentre cross-sectional was conducted between January September 2022 town Douala. Patients were consecutively recruited, data interest...

Background and aim: Vitamin D deficiency (VDD) is a global public health problem in African populations. This study aimed at determining the prevalence, characteristics, determinants of VDD era SARS-CoV-2/COVID-19. was conducted from January to September 2022 seven facilities Douala, Cameroon.Methods: A structured pre-tested questionnaire administered each participant collect participants’ information. Molecular detection SARS-CoV-2 genome done. Serum level 25-hydroxyvitamin < 20 ng/mL used...

This study aimed at providing an update of SARS–CoV–2 epidemiology in Douala, the most populated and highly heterogeneous town Cameroon. A hospital–based cross sectional was conducted from January to September 2022. questionnaire used collect sociodemographic, anthropometric, clinical data. Retrotranscriptase quantitative polymerase chain reaction detect nasopharyngeal samples. Of 2354 individuals approached, 420 were included. The mean age patients 42.3 ± 14.4 years (range 21 – 82)....