Huihui Li

ORCID: 0000-0003-4335-6050
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About
Contact & Profiles
Research Areas
  • Acute Myeloid Leukemia Research
  • Blood disorders and treatments
  • Immune Cell Function and Interaction
  • Iron Metabolism and Disorders
  • Immune cells in cancer
  • Erythrocyte Function and Pathophysiology
  • Blood groups and transfusion
  • Hemoglobinopathies and Related Disorders
  • Hematopoietic Stem Cell Transplantation

Albert Einstein College of Medicine
2022-2024

Hematopoietic stem cells (HSCs) are routinely mobilized from the bone marrow (BM) to blood circulation for clinical transplantation. However, precise mechanisms by which individual exit not understood. This study identified cell-extrinsic and molecular determinants of a mobilizable pool blood-forming cells. We found that subset HSCs displays macrophage-associated markers on their cell surface. Although fully functional, these selectively niche-retained as opposed lacking macrophage markers,...

10.1126/science.adp2065 article EN Science 2024-08-08
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