A5037497626- Head and Neck Cancer Studies
- Reconstructive Surgery and Microvascular Techniques
- Tracheal and airway disorders
- Head and Neck Surgical Oncology
- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Dysphagia Assessment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Voice and Speech Disorders
- Cleft Lip and Palate Research
- Pancreatitis Pathology and Treatment
- Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Bone fractures and treatments
- Hip and Femur Fractures
- Reconstructive Facial Surgery Techniques
- Oral and Maxillofacial Pathology
- Airway Management and Intubation Techniques
- IgG4-Related and Inflammatory Diseases
- Global Health and Surgery
- Radiomics and Machine Learning in Medical Imaging
- Medical Education and Admissions
- Surgical site infection prevention
- Lung Cancer Diagnosis and Treatment
- Pancreatic function and diabetes
Vanderbilt University Medical Center
2016-2025
University of Rostock
2012-2025
Vanderbilt University
2013-2024
American Academy of Otolaryngology — Head and Neck Surgery
2023
Temple University
2023
AID Atlanta
2023
Harvard University
2023
Vanderbilt-Ingram Cancer Center
2022
Institute for ImplantTechnology and Biomaterials
2018
Universitätsmedizin Rostock
2017
Surgical treatment comparisons in rare diseases are difficult secondary to the geographic distribution of patients. Fortunately, emerging technologies offer promise reduce these barriers for research.To prospectively compare outcomes 3 most common surgical approaches idiopathic subglottic stenosis (iSGS), a airway disease.In this international, prospective, 3-year multicenter cohort study, 810 patients with untreated, newly diagnosed, or previously treated iSGS were enrolled after undergoing...
Importance Definitive diagnosis of a thyroid nodule in child is obtained through diagnostic surgery. This problematic because pediatric surgery associated with higher rates complications. In adults, preoperative molecular testing improves the management nodules, but this has not been validated children. Objective To determine whether landscape nodules amenable to detection by multigene genomic classifier (GC) test (ThyroSeq v3; Sonic Healthcare USA). Design, Setting, and Participants was...
<h3>Importance</h3> Given that early-stage oral cavity squamous cell carcinoma (OCSCC) has a high propensity for subclinical nodal metastasis, elective neck dissection become standard practice many patients with clinically negative nodes. Unfortunately, most without regional this risk-averse treatment paradigm results in unnecessary morbidity. <h3>Objectives</h3> To develop and validate predictive models of occult metastasis from clinicopathological variables were available after surgical...
Abstract The North American Airway Collaborative (NoAAC) previously published a 3‐year multi‐institutional prospective cohort study showing variation in treatment effectiveness between 3 primary surgical techniques for idiopathic subglottic stenosis (iSGS). In this report, we update these findings to include 5 years of data evaluating effectiveness. Patients the NoAAC were re‐enrolled 2 additional and followed using prespecified protocol. Consistent with prior data, observation 487 iSGS...
Early studies estimate that 5% to 10% of oropharyngeal squamous cell carcinomas overexpress p16 but are unassociated with transcriptionally-active high-risk human papillomavirus (HPV). Patients discordant HPV testing may experience clinical outcomes differ from traditional expectations. To document the rate and mRNA positivity, characterize patients testing, identify features warrant selective use HPV-specific after IHC, a multi-institutional, retrospective review carcinoma IHC by reverse...
Abstract Background Numerous challenges exist in determining surgical margin status. Communication between surgeons and pathologists is crucial for specimen orientation accurate assessment. Methods A prospective study to determine feasibility of incorporating three‐dimensional (3D) scanning into pathology workflow was performed. structured‐light 3D scanner captured the photorealistic surface topography fresh specimens. Computer‐aided design (CAD) software used document sites sampling...
Objective Total laryngectomy (TL) is a high-cost procedure with patients at risk for significant postoperative health care use. Face-to-face preoperative counseling provided by speech-language pathologists relatively inexpensive intervention that may improve quality and decrease costs. We evaluated if undergoing TL was associated differences in length of stay (LOS), use the emergency department (ED), or unplanned readmissions within 30 days discharge. A secondary analysis identified...
Genomic and transcriptomic analysis has furthered our understanding of many tumors. Yet, thyroid cancer management is largely guided by staging histology, with few molecular prognostic treatment biomarkers. Here, we utilize a large cohort 251 patients 312 samples from two tertiary medical centers perform DNA/RNA sequencing, spatial transcriptomics, multiplex immunofluorescence to identify biomarkers aggressive malignancy. We high-risk mutations discover unique signature disease, the...
Abstract Introduction H‐index is a widely used metric quantifying researcher's productivity and impact based on an author's publications citations. Though convenient to calculate, h‐index fails incorporate collaborations interrelationships between physicians into its assessment of academic impact, leading limited insight grouped networks. We present social network analysis as tool measure relationships quantify their impact. Methods A bibliometric multicenter was conducted physician faculty...
ABSTRACT Background Time from surgery to initiation of postoperative radiation therapy (PORT) less than 6 weeks was recently instituted as the first quality metric within head and neck cancer care. Methods We performed a retrospective single institution cohort study investigate predictors PORT delay impact on survival. Results rate 73.2%, with median time treatment 51 days. Outside facility independently associated increased likelihood (OR 1.94, 95% CI 1.03–3.74, p = 0.043). location did not...
The treatment summary (TS) remains underused in head and neck cancer (HNC). We determine if receiving a personalized TS following definitive HNC improves patient recall of details. A history questionnaire was administered to assess accuracy reporting diagnosis treatment-related details at baseline (pre-TS) 1-month follow-up (post-TS). Statistical significance changes assessed using McNemar's chi squared test. One hundred participants were enrolled between January December 2022. Ninety-one...
Abstract Objective Determine relationships between pain and mental health disorders (MHDs) in patients undergoing microvascular free flap reconstruction for head neck cancer (HNC). Study Design Retrospective cohort. Setting Tertiary Care Institution the Southeastern United States. Methods Clinical data were manually abstracted from digital records to obtain demographic, MHD, clinical outcomes, HNC who underwent 2017 2023. Univariate multivariable regression analyses performed delineate MHDs...
ABSTRACT Objectives The osteocutaneous radial forearm free flap (OCRFFF) is used for the reconstruction of bony head and neck defects. Being a weight‐bearing bone, precise harvesting radius required to maintain structural integrity, postoperative function, prevent fracture. A cutting guide may allow surgeons be more confident in performing harvest, improve allocation orthopedic specialist resources. Methods custom was developed an iterative process with six one hand surgeon. Following design...