A5103039451- Ocular Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- Yersinia bacterium, plague, ectoparasites research
- Gut microbiota and health
- Intraocular Surgery and Lenses
- Sinusitis and nasal conditions
- Antifungal resistance and susceptibility
- Ocular Diseases and Behçet’s Syndrome
- Child Nutrition and Feeding Issues
- Child Nutrition and Water Access
- Anorectal Disease Treatments and Outcomes
- Urologic and reproductive health conditions
- Infective Endocarditis Diagnosis and Management
Shandong Eye Hospital
2016-2022
Shandong First Medical University
2016-2022
Second Affiliated Hospital of Jilin University
2020
University of Jinan
2016
AIM: To investigate the ocular surface microbiome profile of patients with fungal keratitis (FK) through bacterial 16S rDNA sequencing. METHODS: The swab samples were collected from 8 FK (Group 1 corneal ulcer, Group 2 conjunctival sac infected eyes, and 3 fellow eyes) 10 healthy eyes 4 sac). Bacterial V4-V5 region sequencing was performed to characterize communities on surfaces FK. RESULTS: Our metagenomic data showed that 97% sequence reads categorized into 245 distinct genera, 67.75±7.79...
Objective: Intended to investigate the epidemiological characteristics, risk factors and incidence trend of endophthalmitis after cataract surgery in recent 12 years. Methods: A retrospective study was conducted on patients who underwent Qingdao Eye Hospital from January 1, 2008, December 31, 2019, including age, sex, history diabetes, intraoperative operation complications. In addition, related acute infective were analyzed. The its analyzed by univariate multivariate logistic regression...
Bacteria associated with postoperative endophthalmitis mostly originate from the normal bacterial flora of patient’s conjunctiva and eyelids, so incidence may be reduced by eliminating ocular adnexal before surgery. We assessed effectiveness eyedrops 0.5% levofloxacin 5.0% povidone-iodine (PVI) in reducing conjunctival metagenomic analysis. A total 2.4 × 10 6 high-quality sequencing reads were generated 93 samples obtained 31 eyes scheduled for cataract surgery prophylactic therapy (group...
Autism spectrum disorder (ASD) is a developmental disability which may cause significant social, communication, and behavioral challenges. Besides certain essential symptoms, lot of ASD individuals also suffer the comorbidity gut microbiota dysbiosis, possibly causes variety gastrointestinal (GI) difficulties. Interestingly, evidence has indicated that output be modulated through communication between central nervous system via gut-brain axis. Polyunsaturated fatty acids (PUFAs) n-3 (n-3...
Background Epithelial-mesenchymal transition (EMT) is one of the pathogenesis mechanisms posterior capule opcification (PCO). Studying EMT important significance for prevention and treatment PCO.However, model lack. Objective This study was to establish an in vitro human PCO. Methods In mimic cataract enucleation performed on 40 donor eyes, including anterior capsulorhexis, nucleus hydroexpression, aspiration lens fibers.The capsular bag dissected free during surgery pinned flat...
Background Endophthalmitis is a serious complication of intraocular surgery.Conventional identification methods for bacteria are becterial culture and smear method, but these laboratory tests spend long time have low positive rates.16S rDNA the bacterial chromosome encoding ribosomal RNA sequences, it determined that 16S sequencing has high specificity bacteria. Objective This study was to identify infectious from aqueous humor or vitreous body in eyes with endophthalmitis by...