A5058889819- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Nutrition and Health in Aging
- Obesity, Physical Activity, Diet
- Body Contouring and Surgery
- Nutritional Studies and Diet
- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Magnesium in Health and Disease
- Parathyroid Disorders and Treatments
- Health and Lifestyle Studies
- Esophageal and GI Pathology
- Cardiovascular Disease and Adiposity
- Regulation of Appetite and Obesity
- Eating Disorders and Behaviors
- Biochemical Analysis and Sensing Techniques
- Diet, Metabolism, and Disease
- Folate and B Vitamins Research
- Nuts composition and effects
- Metabolism, Diabetes, and Cancer
- Horticultural and Viticultural Research
- Diabetes Management and Research
- Obesity and Health Practices
- Sulfur Compounds in Biology
- Diabetes Treatment and Management
Indiana University Bloomington
2019-2025
Indiana University
2021-2022
Indiana University – Purdue University Indianapolis
2021
Purdue University West Lafayette
2011-2019
State Street (United States)
2013-2017
RELX Group (United States)
2017
Philadelphia University
2017
RELX Group (United Kingdom)
2017
Emory University
2001-2011
Emory University Hospital
2008
Roux-en-y gastric bypass (RYGB) surgery is associated with dramatic improvements in obesity-related comorbidity, but also nutritional deficiencies. Vitamin D concentrations are depressed the severely obese, impact of weight loss via RYGB unknown. We determined associations between adiposity and systemic 25-hydroxyvitamin (25(OH)D) during immediate longer-term effects RYGB. Plasma 25(OH)D fat mass (FAT) were by immunoassay air displacement plethysmography, respectively, at 0 (before surgery),...
Summary Background and objectives The significance of renal parenchymal volume the factors that influence it are poorly understood. Design, setting, participants, & measurements Renal (RPV) was measured on contrast-enhanced CT scans after exclusion sinus fat vessels in 224 healthy subjects evaluated as kidney donors a separate cohort 22 severely obese individuals before 6 months weight loss. GFR by iohexol clearance 76 transplant donors. RPV correlated with age, GFR, various...
Obesity-related glucose intolerance is a function of hepatic (homeostatic model assessment-insulin resistance [HOMA-IR]) and peripheral insulin (Si) β-cell dysfunction. We determined relationships between changes in these measures, visceral (VAT) subcutaneous (SAT) adipose tissue, systemic adipocytokine biomarkers 1 6 months after surgical weight loss. HOMA-IR decreased significantly (−50%) from baseline by month further (−67%) months, Si was improved (2.3-fold) Plasma concentrations leptin...
It is not known whether there are mechanisms linking adipose tissue mass and increased oxidative stress in obesity. This study investigated associations between decreasing general abdominal fat depots during weight loss. Subjects were severely obese women who measured serially at baseline 1, 6 (n = 30), 24 months 18) after bariatric surgery. Total (FAT) volumes of visceral (VAT) subcutaneous (SAT) related to plasma concentrations derivatives reactive metabolites (dROMS), a measure lipid...
Glycemic disorders resolve following Roux-en-Y gastric bypass (RYGB) surgery, but early and longer-term mechanisms regarding effects on β-cell dysfunction as well relationships with decreasing adiposity are not understood. We evaluated longitudinal changes in peripheral insulin sensitivity (Si), the acute response to glucose (AIRg), composite estimate of function, disposition index (DI), over 24 mo via frequently sampled intravenous tolerance testing severely obese women who had fasting...
This cohort study examines the association between COVID-19 pandemic restrictions and obesity prevalence among youths aged 2 to 19 years in Monroe County, Indiana.
Background: Limited high-quality evidence exists from randomized controlled trials on the impact of an avocado-containing diet cardiometabolic risk factors. Objective: The purpose this randomized, double-blind, outpatient, feeding, crossover study (NCT04990817) in adults with increased was to assess effects replacing energy solid fats and added sugars one avocado blood lipids other indicators health. Methods: For two 3-week periods separated by a 2-week washout, 42 healthy elevated...
Resolution of Type-2 diabetes mellitus (DM) after weight loss surgery is well documented, but the mechanism elusive. We evaluated glucose-insulin metabolism patients undergoing a Roux-en-Y gastric bypass (RYGB) using intravenous glucose tolerance test (IVGTT) and compared it with who underwent laparoscopic adjustable band (AB) placement. Thirty-one female (age range, 20 to 50 years; body mass index, 47.2 kg/m 2 ) RYGB. Nine AB placement served as control subjects. All IVGTT at baseline 1...
Recurrence of incisional hernia may be as high 50 per cent. Abnormal collagen I/III ratios have been observed within scar tissue patients with recurrent hernias. We sought to determine whether composition in primary, nonscarred was similarly affected these patients. In this prospective, case-control study, nonscarred, primary abdominal wall skin and fascia biopsies were obtained 12 a history hernias 11 control subjects without any while undergoing laparoscopic surgery. Tissue protein...