- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- COVID-19 and healthcare impacts
- Peripheral Artery Disease Management
- Listeria monocytogenes in Food Safety
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Cardiovascular Disease and Adiposity
- Appendicitis Diagnosis and Management
- Bacterial Infections and Vaccines
- Respiratory Support and Mechanisms
- Pharmacological Effects and Toxicity Studies
- Electrohydrodynamics and Fluid Dynamics
- Ultrasound in Clinical Applications
- Antiplatelet Therapy and Cardiovascular Diseases
- Antimicrobial Resistance in Staphylococcus
- Acute Ischemic Stroke Management
- Hemoglobinopathies and Related Disorders
- Synthesis and biological activity
- Pain Management and Treatment
- Acute Kidney Injury Research
Cairo University
2013-2025
Al-Azhar University
2014-2025
Aswan University
2017-2025
Magdi Yacoub Heart Foundation
2022-2024
Minneapolis Heart Institute Foundation
2023
University of Göttingen
2022
University of Birmingham
2022
National Heart Institute
2022
National Institute for Health Research
2022
University of Veterinary Medicine
2019
Minimal data are available on the combined two oral iron chelators in β-thalassemia major (β-TM). Comparison of safety, efficacy, compliance, treatment satisfaction, and quality life (QoL) regimens: deferiprone (DFP) deferoxamine (DFO) versus DFP deferasirox (DFX) were studied.A prospective randomized trial (NCT01511848) was conducted 96 young β-TM patients with severe overload. Patients to receive either DFO (arm 1) or DFX 2). Efficacy endpoints difference between groups change serum...
Goat and sheep milk is consumed by human populations throughout the world; as a result, it has been proposed an alternative, nutrient-rich to feed infants allergic cow's milk. Unfortunately, potentially harmful bacteria have not thoroughly tested in goat or Listeria monocytogenes bacterium that causes adverse health effects if ingested humans. The purpose of this study was estimate prevalence characterize phenotype, genotype, virulence factors, biofilm formation, antibiopotential isolated...
Contrast-induced nephropathy (CIN) remains a serious complication following percutaneous coronary intervention (PCI), often leading to poor outcomes. Although the overall incidence of CIN is low, risk can be significantly higher in certain susceptible cohorts. This prospective observational analytic study enrolled 174 consecutive eligible patients. The selectively included diabetic patients with heart failure who are receiving regular diuretic therapy, being scheduled for elective...
Intravascular leiomyomatosis (IVL) is a rare benign tumor capable of hematogenous spread. Clinical presentation heterogeneous depending on the destination organ, which often delays identification. Key steps: A 38-year-old female with recent history hysterectomy presented dyspnea and dizziness. Initial workup revealed huge obstructive growth in right heart chambers. thrombus-in-transit was most likely preliminary diagnosis. Further thorough assessment reduced likelihood thrombus increased...
INTRODUCTION: Diabetes Mellitus (DM) often leads to diabetic neuropathy (DN), particularly Diabetic Peripheral Neuropathy (DPN), causing significant pain and discomfort. Despite available pharmacological treatments, many patients remain untreated or experience intolerable side effects. METHODS: A comprehensive search strategy was implemented through March 26, 2024, across five databases (PubMed, Scopus, WOS, Embase, Cochrane CENTRAL), identifying studies relevant SCC PDN. Eligibility...
Infective endocarditis (IE) is commonly complicated by cerebral embolization and hemorrhage secondary to intracranial mycotic aneurysms (ICMAs). These complications are associated with poor outcome may require diagnostic therapeutic plans be modified. However, routine screening brain CT angiography (CTA) not standard practice. We aimed study the impact of CTA on treatment decisions for patients IE.From July 2007 December 2012, we prospectively recruited 81 consecutive definite left-sided IE...
Coronary artery disease (CAD) is the commonest cause of death worldwide. ST-segment elevation myocardial infarction (STEMI) and its consequences can be devastating particularly at younger age for a bigger impact on patient's psychology ability to work. Little known about differential features outcomes young STEMI patients in Egypt. This study characterized (≤ 45 years) compared > years evaluated 1-year outcomes.A total 492 eligible who presented National Heart Institute Cairo University...
Benzotriazole and microwave mediated syntheses led to a new set of hybrid conjugates pyrazinoic acid with isoniazid via amino linkers in excellent yields retention chirality. Microbiological screening the synthesized revealed an exceptionally high activity against some pathogenic bacterial strains at low concentrations. Promising antimycobacterial properties were observed tuberculous non-tuberculous mycobacteria. Robust molecular models (2D-QSAR 3D-pharmacophore) support biological...
In patients presenting with ST-segment elevation myocardial infarction (STEMI), the prevalence of having concomitant severe non-culprit lesion(s) is ≥40%. While timely primary PCI (pPCI) for culprit lesion standard practice, management lesions remains unsettled.
Abstract Background When heart failure with reduced ejection fraction (HFrEF) and chronic kidney disease (CKD) co-exist, Renin angiotensin-aldosterone system inhibitors (RAASi) are often underutilized for the fear of worsening renal function (WRF). Telmisartan is a RAASi characteristic favorable profile, although data on its utility in HFrEF limited. This study aimed to compare efficacy tolerability versus Enalapril patients CKD. Results randomized 107 CKD either (10–80 mg) or (5–40 daily....
Abstract Background Final infarct size (IS) after ST segment elevation myocardial infarction (STEMI) is a major predictor of mortality. Seeking early predictors for final IS can guide individualized therapeutic strategies those recognized to be at higher risk. Results Eighty STEMI patients successfully treated with primary percutaneous coronary intervention (pPCI) underwent baseline (within 48 h) 2D, 3D echocardiography speckle tracking and then cardiac magnetic resonance (CMR) 3 months...
Aim: To show that the classic Knapp procedure when used for treatment of monocular elevation deficiency may not correct it completely especially associated with pseudoptosis and to suggest a option. Methods: Thirteen patients (2 6 years) congenital (MED) were studied. All had hypotropia, pseudoptosis, absent above primary position negative forced duction test affected eye. Medial lateral rectus muscles elevated via procedure. Two months later, inferior muscle non-affected eye was resected m...
Few data are available on the characteristics of infective endocarditis (IE) cases in Egypt. The aim this work is to describe and outcomes IE patients evaluate temporal changes diagnostic therapeutic aspects over 11 years.
Abstract Background ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (pPCI) are at increased risk for contrast-induced nephropathy (CIN) than elective PCI procedures. Routine calculation of Mehran’s score is limited by its complexity and difficulty to memorize. This study evaluated CHA 2 DS -VASc predictive utility CIN in STEMI before pPCI. Results Consecutive 500 acute presenting two Egyptian pPCI centers were recruited. Exclusion...