- Advancements in Semiconductor Devices and Circuit Design
- Semiconductor materials and devices
- Silicon Carbide Semiconductor Technologies
- Spaceflight effects on biology
- Reproductive Biology and Fertility
- Tracheal and airway disorders
- Tissue Engineering and Regenerative Medicine
- Medical Imaging Techniques and Applications
- Birth, Development, and Health
- Radio Frequency Integrated Circuit Design
- Integrated Circuits and Semiconductor Failure Analysis
- Sperm and Testicular Function
- Heart Rate Variability and Autonomic Control
- High Altitude and Hypoxia
- Cardiac Imaging and Diagnostics
- Seaweed-derived Bioactive Compounds
- Radioactive contamination and transfer
- Nuclear Physics and Applications
- Cardiovascular Health and Disease Prevention
- Anesthesia and Neurotoxicity Research
- Radioactivity and Radon Measurements
- Thin-Film Transistor Technologies
- Photonic and Optical Devices
- Electrostatic Discharge in Electronics
- Semiconductor materials and interfaces
Fukushima Medical University
2009-2024
Japan Atomic Energy Agency
2019-2023
Kyoto University of Advanced Science
2017
Hiroshima University
1999-2013
Osaka University
2013
Kyoto University
1976-2010
Kobe University
1994-2009
Hiroshima University of Economics
2007-2008
University of Bristol
2007
Tokyo Institute of Technology
2004-2006
Preantral follicles containing oocytes of 70–89.5 μm in diameter were isolated from pig ovaries and cultured collagen gel for up to 16 days, the presence serum, FSH oestradiol. Formation follicular antra occurred as culture proceeded. The had been enclosed by granulosa cells contacts between processes enclosing cumulus maintained over period. After days culture, 30–40% normal appearance, diameters about half these larger than 100 μm. When grown vitro liberated a further 48 h modified...
Carrageenan is a sulfated polysaccharide that exists in red seaweeds recently shown to have anticancer properties. Previous findings show various effects of carrageenan suppressing tumor cell growth. One the hallmarks cancer uncontrolled proliferation, consequence loss normal cell-cycle control, underlies Recently there an increasing interest potential agents affect cycle cells. Thus, this study we investigated on cycle.
The compact MOSFET model development trend leads to models based on the channel surface potential, allowing higher accuracy and a reduced number of parameters. Among these, Hiroshima University Semiconductor Technology Academic Research Center IGFET Model (HiSIM) solves potentials with an efficient physically correct iteration procedure, thus avoiding additional approximations without any computer run-time penalty. It is further demonstrated that excellent for higher-order phenomena, which...
Junctional adhesion molecule-1 (JAM-1) forms part of the tight junction between adjacent endothelial cells. Using microarray technology, we showed previously that JAM-1 was differentially expressed in brain stem spontaneously hypertensive rats compared with normotensive Wistar–Kyoto (WKY) rats. In this study, quantified expression and WKY established whether any differential confined to region or ubiquitous throughout central nervous system and, indeed, whole body. Because nucleus tractus...
Deep-sea water is rich in minerals, e.g., Mg, Ca, and K which have been considered to be associated with prevention of cardiovascular disease. We investigated the effect deep-sea on hemodynamics Kurosawa Kusanagi-Hypercholesterolemic (KHC) rabbits. was pumped offing Cape Muroto Japan mineral constituents were refined a degree hardness 1000. Twenty four 4-month-old KHC rabbits given (n=12) tap for 6 months. Pressure flow waves at ascending aorta recorded under pentobarbital anesthesia....
A three-terminal superconducting device composed of a semiconductor-coupled Josephson junction and an oxide-insulated gate is fabricated. p-type Si single-crystal film having 100-nm thickness used for the semiconductor layer. Two electrodes correspond to source drain device. tunneling current flows between electrodes, controlled by bias voltage.
Several artificial grafts for covering deficient trachea have been produced through tissue engineering. Recently, our group clinically used an made from collagen sponge patients with noncircumferential tracheal resection. However, the slowness of epithelial regeneration on surface was confirmed as one particular problem. In this study, we co-cultured cells fibroblasts and examined effects in vitro. Fibroblasts activated cell proliferation migration. co-culture fibroblasts, reconstructed...
This paper reviews the industry-standard surface-potential-based compact model HiSIM_HV for high-voltage MOSFETs, as, e.g., lateral double-diffused MOS transistor, and introduces important improvements implemented in second-generation versions (HiSIM_HV2), which open source code has been released since October 2011. solves Poisson equation consistently within intrinsic MOSFET, i.e., gate-drift overlap region drain-side part of drift region. Excess carrier concentrations are accurately...
Although povidone-iodine (PVP-I) has been used as a gargle since 1956, its effectiveness and material safety have remained controversial. The aim of this study was to investigate the toxicity PVP-I epithelial cells in concentration range significantly lower than that clinically. Study design vitro laboratory investigations vivo histological immunologic analysis. We examined effects at concentrations 1 × 10−2 103 μM 10−4 10 on HeLa model rat oral mucosa, respectively, after or 2 days...
Sunscreens today contain several synthetic UV (Ultraviolet) filter molecules to protect the skin epidermis from radiation damage. However, these may create negative effects on human skin. Due this condition, there is an increase in development of natural products replace uses chemicals. Brown macroalgae Sargassum has been recently studied for its photoprotective activities. The purpose study investigate activity one most abundant species Lombok coast; cristaefolium. Spectrophotometry...
The treatment of laryngotracheal stenosis remains a challenge as often requires multistaged procedures, and successful decannulation sometimes fails after series operations. Induced pluripotent stem cells (iPSCs) were generated in 2006. These are capable unlimited symmetrical self-renewal, thus providing an cell source for tissue-engineering applications. We have previously reported tracheal wall regeneration using three-dimensional (3D) scaffold containing iPSCs. However, the efficiency...
Copper metallization was applied to quarter-micron CMOS circuits using copper chemical vapor deposition (CVD) and mechanical polishing (CMP). Both the process electrical characteristics of devices/circuits were evaluated. Process-induced metal contamination on both sides wafer quantitatively evaluated reduced about 10/sup 11/ atoms/cm/sup 2/ by an optimized cleaning sequence. The ability borophosphosilicate-glass (BPSG) act as a diffusion barrier discovered TiN do so also confirmed....
Hot-carrier-induced device degradation has been studied for quarter-micrometer level buried-channel PMOSFETs. It was found that the major hot-carrier mode these small devices is quite different from previously reported, which caused by trapped electrons injected into gate oxide. The new effect of interface traps generated hot hole injection oxide near drain in saturation region. DC lifetime can be evaluated using substrate current rather than as a predictor. Interface-trap generation due to...
In this paper, a compact model of nonquasi-static (NQS) carrier-transport effects in MOSFETs is reported, which takes into account the carrier-response delay to form channel. The NQS model, as implemented surface-potential-based MOSFET Hiroshima University STARC IGFET verified predict correct transient terminal currents and achieve stable circuit simulation. Simulation results show that can even reduce simulation time some cases due elimination unphysical overshoot peaks normally calculated...
Objectives: The slowness of epithelialization on the artificial trachea that has been successfully used in humans is a problem. purpose this study was to develop way regenerate epithelium surface trachea. Methods: In an vitro study, isolated rat tracheal epithelial cells were seeded collagenous gel stratified sponge. Histologic and immunohistochemical examinations made. vivo we transplanted grafts with green fluorescent protein–positive onto defects normal rats. At 3, 7, 14, 30 days after...
The fabrication of p-channel and n-channel MOSFETs with sub-quarter-micrometer n/sup +/ polysilicon gates, have been fabricated using extremely shallow source-drain (S-D) junctions, is reported p/sup +/-n junctions as 80 nm preamorphization low-energy BF/sub 2/ ion implantation rapid thermal annealing, 80-nm +/-p arsenic annealing. 80-mm S-D 0.16- mu m gate lengths fabricated, a maximum transconductance 400 mS/mm has obtained. 51-stage enhancement-mode/enhancement-mode (E/E) ring oscillators...
The tracheal epithelium maintains the health of respiratory tract through mucociliary clearance and regulation ion water balance. When trachea is surgically removed, artificial grafts have been clinically used by our group to regenerate trachea. In such cases, needs 2 months for functional regeneration. Previous study has shown that fibroblasts facilitate epithelial this study, heterotopic originating from dermis, nasal, gingival mucosa were cocultured with cells evaluate their potential as...
Objectives Although our group has had mostly successful results with clinical application of a tracheal prosthesis, delayed epithelial regeneration remains problem. In previous studies using rats, it was demonstrated that fibroblasts accelerated proliferation and differentiation the epithelium in vitro vivo. The purpose this study to evaluate effects on larger defects rabbits. Methods We developed bioengineered scaffold, luminal surface which coated fibroblasts. This scaffold implanted into...
Although our group has had mostly successful results with clinical application of a tracheal prosthesis, delayed epithelial regeneration remains problem. In previous studies using rats, it was demonstrated that fibroblasts accelerated proliferation and differentiation the epithelium in vitro vivo. The purpose this study to evaluate effects on larger defects rabbits.We developed bioengineered scaffold, luminal surface which coated fibroblasts. This scaffold implanted into 12 rabbits...