- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Renal and Vascular Pathologies
- Venous Thromboembolism Diagnosis and Management
- Congenital Heart Disease Studies
- Peripheral Artery Disease Management
- Intracranial Aneurysms: Treatment and Complications
- Brain Tumor Detection and Classification
- Cerebral Venous Sinus Thrombosis
- Cardiovascular and Diving-Related Complications
- Trypanosoma species research and implications
- Vascular anomalies and interventions
- Cardiovascular Health and Disease Prevention
- Case Reports on Hematomas
- Organ Donation and Transplantation
- Spatial Neglect and Hemispheric Dysfunction
- Physical Education and Training Studies
- Martial Arts: Techniques, Psychology, and Education
- Hospital Admissions and Outcomes
- Congenital Anomalies and Fetal Surgery
- Coenzyme Q10 studies and effects
- Cardiomyopathy and Myosin Studies
Hospital Dr. Nélio Mendonça
2024-2025
Instituto de Neurociências e Comportamento
2024
Universidade de São Paulo
2013-2024
Neurological Surgery
2024
Hospital Israelita Albert Einstein
2022
Emory University
2018-2021
Grady Memorial Hospital
2018-2021
Universidade de Ribeirão Preto
2015-2019
Emory and Henry College
2018-2019
The University of Sydney
2017-2018
Background and Purpose— Endovascular therapy is the standard of care for treatment proximal large vessel occlusion strokes. Its safety efficacy in distal intracranial occlusions has not been well studied. Methods— The data that support findings this study are available from corresponding author on reasonable request. Retrospective review a prospectively collected endovascular database (2010–2015, n=949) all patients with treated endovascularly. Distal were defined as any segment anterior...
A carotid web (CaW) is a shelf-like lesion in the posterior aspect of internal bulb and represents an intimal variant fibromuscular dysplasia. CaW has been associated with recurrent strokes conventionally treated surgical excision. We report multicenter experience stenting patients symptomatic CaWs.Retrospective review consecutive admitted to 5 comprehensive stroke centers who were identified have stenting. was defined by presence shelf-like/linear, smooth filling defect diagnosed neck CT...
Purpose: Carotid web (CaW) is an underrecognized cause of cryptogenic stroke in young patients. The optimal imaging for CaW unknown. We aim to evaluate the diagnostic accuracy diverse modalities diagnosis CaW. Methods: Retrospective analysis institutional neurovascular database was performed identify patients with multimodal (CT angiogram-CTA, digital subtraction angiogram-DSA, and/or ultrasound-US) or atherosclerosis. Baseline clinical demographics were recorded. Blinded image each modality...
Background Longer stent retrievers have recently become available and theoretical advantages over their shorter counterparts. We aim to evaluate whether retriever length impacts reperfusion rates in stroke thrombectomy. Methods This was a retrospective analysis of prospectively collected thrombectomy database which equal diameter (4 mm) were used as the first-line strategy for intracranial internal carotid or middle cerebral artery M1 M2 occlusions along with balloon guide catheter from June...
The Guidelines for Stroke Rehabilitation are the result of a joint effort by Scientific Department Neurological Brazilian Academy Neurology aiming to guide professionals involved in rehabilitation process reduce functional disability and increase individual autonomy. Members group participated web discussion forums with predefined themes, followed videoconference meetings which issues were discussed, leading consensus. These guidelines, divided into two parts, focus on implications recent...
Bypassing the emergency department and computed tomography suite by directly transporting to neuroangiography for imaging assessment treatment may shorten reperfusion times while maintaining proper patient selection.To determine whether flat-panel detector multiphase angiography protocol is associated with reduced a similar safety profile as standard protocol.Single-center prospective study of consecutive patients anterior circulation large vessel occlusion strokes transferred our facility...
Expediting notification of lesions in acute ischemic stroke (AIS) is critical. Limited availability experts to assess such and delays large vessel occlusion (LVO) recognition can negatively affect outcomes. Artificial intelligence (AI) may aid LVO treatment. This study aims evaluate the performance an AI-based algorithm for detection AIS.Retrospective analysis a database AIS patients admitted single center between 2014 2019. Vascular neurologists graded computed tomography angiographies...
Background— Carotid artery stenting (CAS) has become an alternative treatment for patients presenting symptomatic carotid stenosis. The improvement in clinical outcomes with CAS been associated the development of embolic protection devices. trial aim is to compare flow reversal versus filter during through femoral access. Methods and Results— Patients were randomly enrolled using or protection. primary end points incidence, number, size new ischemic brain lesions after CAS. secondary...
Introduction: Acute ischemic stroke (AIS) treatment relies on prompt clinical suspicion, neuroimaging findings and neurologists’ referrals, especially for Large Vessel Occlusion (LVO) patients. Recent advances in artificial intelligence have revolutionized the field of computer vision. We propose use artificial-intelligence based algorithm detection LVOs AIS setting. Methods: performed a multi-center retrospective analysis CTAs, randomly picked from prospective cohort adult patients, with...
<h3>Introduction</h3> Large Vessel Occlusion (LVO) for Acute Ischemic Stroke (AIS) remains a public health issue as there is significant morbidity and mortality when left untreated. Timely recognition, therefore, of utmost significance, are validated therapeutic options involving cerebrovascular reperfusion. Best patient care relies on tailored expeditious clinical identification, using multimodal neuroimaging facilitating referrals to comprehensive centers. Artificial Intelligence...
Patients with large vessel occlusion stroke (LVOS) and a low Alberta Stroke Program Early CT Score (ASPECTS) are often not offered endovascular therapy (ET) as they thought to have poor prognosis.To compare the outcomes of patients high ASPECTS undergoing ET based on baseline infarct volumes.Review prospectively collected database at tertiary care center between September 2010 March 2020. All anterior circulation LVOS interpretable perfusion (CTP) were included. Subjects divided into groups...
Background and purpose The optimal selection methodology for stroke thrombectomy beyond 6 hours remains to be established. Methods Review of a prospectively collected database patients with anterior circulation strokes, adequate CT perfusion (CTP) maps, National Institute Health Stroke Scale (NIHSS)≥10 presenting from January 2014 October 2018. Patients were categorised according five paradigms: DAWN clinical-core mismatch (DAWN-CCM): between age-adjusted NIHSS CTP core, DEFUSE 3 imaging...
Age, neurologic deficits, core volume (CV), and clinical or radiographic mismatch are considered in selection for endovascular therapy (ET) anterior circulation emergent large vessel occlusion (aELVO). Semiquantitative CV estimation by Alberta Stroke Programme Early CT Score (CT ASPECTS) quantitative perfusion (CTP) both used paradigms.To compare the prognostic value of CTP with ASPECTS aELVO.Patients an institutional registry who had aELVO, pre-ET National Institutes Health Scale (NIHSS)...
Several reports have described lower mortality rates in overweight or obese patients as compared to normal weight ones. In the past decade, several studies investigated phenomenon, commonly known obesity paradox, with mixed results thus far. We sought determine whether outcomes differ between large vessel occlusion strokes (LVOS) after endovascular therapy (ET) according their body mass index (BMI).We reviewed our prospectively collected database at a tertiary care academic institution. All...
Age and infarct volume are among the most powerful predictors of outcome after large vessel occlusion acute strokes (LVOS).To study impact age-adjusted final (FIV) on functional outcomes.Review a prospectively collected thrombectomy database at tertiary care center between September 2010 February 2018. Consecutive patients with anterior circulation LVOS who achieved full reperfusion (modified Thrombolysis in Cerebral Infarction 3) were categorized into four age groups: (G1) <60 years, (G2)...
<h3>Objective:</h3> To determine the rate of symptomatic intracranial hemorrhage (SIH) and in-hospital mortality among patients with acute ischemic stroke related to Chagas disease (CD) treated IV tissue plasminogen activator (TPA). <h3>Methods:</h3> In this retrospective cohort study, consecutive TPA routinely tested for CD were retrospectively selected from a single-center, hospital-based, prospective registry 2001 2012. Demographic clinical data obtained as well mortality. CT scans...
Symptomatic intracranial hemorrhage represents one of the most feared complications endovascular reperfusion. We aim to describe a series patients that experienced immediate reperfusion injury with active intraprocedural extravasation within territory deep penetrating arteries and provide real-time correlation CT "spot sign."This was retrospective analysis suffered arterial during stroke treatment in two tertiary care centers.Five were identified. Median age 63 (58-71) years, 66% male. NIHSS...
Introduction: The hyperdense vessel sign (HDVS) on non-contrast computed tomography (NCCT) is one of the earliest findings in patients with acute ischemic stroke. Further, HDVS has been associated poor outcomes. Recognition HDVS, which indicates presence and location a red blood cell-rich intra-arterial thrombus, aids diagnosis large occlusions (LVOs) helps triage to endovascular reperfusion. An efficient workflow identify eligible for reperfusion therapy essential achieve best patient...
OBJECTIVES: Carotid artery stenting is an emerging revascularization alternative to carotid endarterectomy.However, guidelines have recommended only if the rate of periprocedural stroke or death , 6% among symptomatic patients and 3% asymptomatic patients.The aim this study evaluate compare clinical outcomes who had undergone as a first-intention treatment.METHOD: A retrospective analysis underwent by our interventional neuroradiology team was conducted.Patients were divided into two groups:...
Background: Thromboaspiration and stent retriever thrombectomy perform similarly in anterior circulation large vessel occlusions. We aim to compare performance of modern thromboaspiration against technology basilar artery Methods: This was a retrospective analysis prospectively collected databank comprehensive stroke center. Inclusion criteria: thrombectomies which stent-retrievers (Trevo or Solitaire) devices (Penumbra 5max, 64 68) were used as the first-line strategy from Sep2010-Mar2017....