Xingzhu Liu

ORCID: 0000-0003-4423-7328
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Research Areas
  • Electrospun Nanofibers in Biomedical Applications
  • 3D Printing in Biomedical Research
  • Bone Tissue Engineering Materials
  • Healthcare Systems and Reforms
  • Healthcare Policy and Management
  • Hydrogels: synthesis, properties, applications
  • Graphene and Nanomaterials Applications
  • Wound Healing and Treatments
  • Global Health Care Issues
  • Silk-based biomaterials and applications
  • Polymer Surface Interaction Studies
  • Surgical Sutures and Adhesives
  • Advanced Photocatalysis Techniques
  • Additive Manufacturing and 3D Printing Technologies
  • TiO2 Photocatalysis and Solar Cells
  • Global Maternal and Child Health
  • Dental Implant Techniques and Outcomes
  • Nanopore and Nanochannel Transport Studies
  • Hepatitis C virus research
  • Nanocluster Synthesis and Applications
  • HIV/AIDS Impact and Responses
  • Advanced Nanomaterials in Catalysis
  • Respiratory viral infections research
  • Circular RNAs in diseases
  • Food Supply Chain Traceability

Beijing Center for Disease Prevention and Control
2024

Suzhou Institute of Nano-tech and Nano-bionics
2021-2024

Chinese Academy of Sciences
2021-2024

Sichuan University
2024

West China Hospital of Sichuan University
2024

Dalian Maritime University
2024

Hangzhou Medical College
2020-2022

Zhejiang University
2022

Okayama University
2019

Abt Global (United States)
2002-2006

Hydrogel composed of Pluronic F127 diacrylate, quaternized chitosan silk fibroin, and tannic acid is able to maintain good tissue adhesion abilities for wound healing.

10.1039/d1tb01871j article EN Journal of Materials Chemistry B 2022-01-01

Bone fractures are common occurrence in clinical settings, creating a high demand for effective repair material. Unfortunately, limited graft availability, donor site morbidities, unpredictable outcomes, immunologic reactions, infection risks, and geometrical mismatching concerns hampered tissue use underscored the need scaffolds more bone reconstructions due to their tunable properties. Significant progress has been carried out past decade fields of nanoceramics synthesis, bioconjugate...

10.1016/j.engreg.2023.10.003 article EN cc-by-nc-nd Engineered Regeneration 2023-10-27

Fabricating an organic–inorganic nanocomposite hydrogel platform with antibacterial, anti-inflammatory, and osteoinductive properties that mimic bone extracellular matrix composition is decisive for guiding development in orthopedic practice.

10.1039/d3tb00641g article EN Journal of Materials Chemistry B 2023-01-01

Hyaluronic acid (HA) based hydrogels are one of most functional natural biomaterials in the field cartilage tissue engineering (CTE). Even with promising advantages HA hydrogels, complicated mechanical properties native have not been realized, and fabricating excellent to make them practical CTE still remains a current challenge. Here, strategy that integrates nanomaterials is shown form hydrogel sufficient loading for production recombination. Cellulose nanofibrils (CNFs) nanomaterial...

10.1021/acs.biomac.1c01063 article EN Biomacromolecules 2021-11-01

Healing bone erosions in rheumatoid arthritis (RA) remains greatly challenging via biomaterial strategies. Given the unsuccessful innate erosion healing due to an inflammatory disorder, over-activated osteoclasts, and impaired osteoblasts differentiation, RA pathogenesis-guided engineering of innovative hydrogel platform is needed for remodeling osteoimmune osteogenic microenvironment healing. Herein, situ adaptable injectable interpenetrating polymer network (IPN) developed through...

10.1002/adhm.202304668 article EN Advanced Healthcare Materials 2024-06-25

Artificial small-diameter blood vessels (SDBVs) are extremely limited in their thrombosis and still present significant clinical challenges worldwide. In recent years, 3D-bio-printing has offered a powerful technique to fabricate vessel channels tissue engineering applications. Hydrogels attractive bio-inks for SDBVs 3D-bio-printing, but they usually weak mechanical properties. To overcome the properties of hydrogel bio-inks, printable human umbilical vein endothelial cell (HUVEC)-laden...

10.1021/acsabm.1c01052 article EN ACS Applied Bio Materials 2021-11-29

Breast cancer is the most prevalent among women, and it characterized by a high rate of tumor development heterogeneity. stem cells (CSCs) may well contribute to these pathological properties, but mechanisms underlying their self-renewal maintenance are still elusive. Here, we found that long noncoding RNA HOTAIR highly expressed in breast CSCs. required for CSC propagation. Mechanistically, demonstrate recruits PRC2 protein complex promoter IκBα inhibit its expression, leading activation...

10.1016/j.jbc.2022.102630 article EN cc-by Journal of Biological Chemistry 2022-10-20

Objective: To explore and construct a 3D bone remodeling research model displaying stability, repeatability, precise simulation of the physiological biochemical environment in vivo . Methods: In this study, bioprinting was used to reconstruction model. Sodium alginate (SA), hydroxyapatite (HA) gelatin (Gel) were mixed into hydrogel as scaffold material. The osteoblast precursor cells MC3T3-E1 osteoclast RAW264.7 seed cells, which may or not be separated by polycarbonate membrane. cytokines...

10.3389/fbioe.2024.1328078 article EN cc-by Frontiers in Bioengineering and Biotechnology 2024-01-19
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