A5101985111- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Intraperitoneal and Appendiceal Malignancies
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Gynecological conditions and treatments
- Estrogen and related hormone effects
- BRCA gene mutations in cancer
- HER2/EGFR in Cancer Research
- Renal cell carcinoma treatment
- Immune Cell Function and Interaction
- Single-cell and spatial transcriptomics
- Cancer Immunotherapy and Biomarkers
- Cancer Treatment and Pharmacology
- Cancer Risks and Factors
- Nitric Oxide and Endothelin Effects
- Renal and related cancers
- Intestinal and Peritoneal Adhesions
- Hormonal Regulation and Hypertension
- Urological Disorders and Treatments
- Renin-Angiotensin System Studies
- Diverticular Disease and Complications
- Urinary and Genital Oncology Studies
- Circular RNAs in diseases
- Adrenal Hormones and Disorders
University of Padua
1996-2025
Health and Human Development (2HD) Research Network
2023
University of Buenos Aires
2001-2002
Weatherford College
1996
We conducted a prospective observational study investigating the clinical relevance of endometrial thickness (ET) and abnormal uterine bleeding (AUB) on cancer (EC) risk in cohort postmenopausal patients undergoing diagnostic hysteroscopy biopsy. Patients were divided into two groups according to indication hysteroscopy: ET_Group (asymptomatic with ≥ 4 mm) AUB_Group (patients history bleeding). further subgroups based (AUB_Subgroup1: ET < mm; AUB_Subgroup2: mm). The primary outcome was...
(1) Background: Endometrial carcinoma (EC) classified as no specific molecular profile (NSMP) represents a heterogeneous group with variable prognoses. This retrospective, single-center study aims to further stratify NSMP ECs tailor treatment strategies and improve outcomes. (2) Methods: From 2020 2023, we collected data on 51 patients diagnosed EC following the introduction of profiling at our institution. Patients were retrospectively analyzed for estrogen receptor (ER) status, histotype,...
Abstract STUDY QUESTION Can patients with uterine smooth muscle tumours of uncertain malignant potential (STUMP) be effectively and safely managed fertility-sparing treatment? SUMMARY ANSWER This multicentre retrospective study demonstrates that management for diagnosed STUMP is both feasible safe. WHAT IS KNOWN ALREADY Few studies, involving a limited number patients, have investigated in women future pregnancy aspirations. DESIGN, SIZE, DURATION was conducted collaboration 13 Italian...
To compare performance of Assessment Different NEoplasias in the adneXa (ADNEX model), Ovarian-Adnexal Reporting and Data System (O-RADS), Simple Rules Risk (SRR) assessment two-step strategy based on application (SR) followed by SRR SR ADNEX pre-operative discrimination between benign malignant adnexal masses (AMs).We conducted a retrospective study from January-2018 to December-2021 which consecutive patients with at AMs were recruited. Accuracy metrics included sensitivity (SE)...
The main aim of our study was to describe the surgical technique and evaluate feasibility, efficacy safety a vaginal-laparoscopic repair (VLR) iatrogenic vesico-vaginal fistulae (VVF). Between April-2009 November-2017, we retrospectively reviewed all clinical, radiological details surgery for benign or malignant disease ended up with VVF. All patients were diagnosed by CT urogram, cystogram clinical test. standardised is described here. Eighteen developed VVF after hysterectomy, three...
Background: The Endometriosis Fertility Index (EFI), is a crucial validated surgical tool used for predicting fertility outcomes in women with endometriosis. This study aims to assess the concordance between preoperative clinical and instrumental EFI evaluation (uEFI) score obtained during an exploratory laparoscopy prior surgery (sEFI). Methods: presents preliminary data from broader observational cohort study. Least Function uEFI was calculated using modified version of original by...
Ovarian cancer (OC) exhibits an aggressive behavior, wherein the therapeutic approach always involves both surgery and chemotherapy. Survival outcomes are still related to comprehensive surgical excision of all macroscopic lesions (Rauh-Hain et al., 2017), increasing gynecologic oncologists' efforts achieve highest possible complete resection rate (Tozzi 2024). The peritoneum serves as a dissemination pathway barrier that restricts tumor spread beyond its confines. This understanding has...
We aimed to compare the clinical utility and diagnostic accuracy of ADNEX model, ROMA score, RMI I, IV, as well two serum markers (CA125 HE4) in preoperative discrimination between benign malignant adnexal masses (AMs).
This study provides a comprehensive overview of the role immunotherapy in treatment mismatch repair-deficient (MMRd) endometrial carcinomas. Immunotherapy has emerged as transformative approach MMRd due to high mutation rate and subsequent PD-1/PD-L1 overexpression seen these tumors. review analyzes current landscape existing randomized clinical trials, highlighting efficacy immune checkpoint inhibitors (ICIs) like pembrolizumab, avelumab, dostarlimab. Additionally, focus extends potential...