A5075513628- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Esophageal and GI Pathology
- Colorectal Cancer Surgical Treatments
- Gastrointestinal disorders and treatments
- Genetic factors in colorectal cancer
- Esophageal Cancer Research and Treatment
- Diverticular Disease and Complications
- Dysphagia Assessment and Management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Gastroesophageal reflux and treatments
- Radiomics and Machine Learning in Medical Imaging
- Helicobacter pylori-related gastroenterology studies
- Tracheal and airway disorders
- Colorectal and Anal Carcinomas
- Lung Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Lung Cancer Treatments and Mutations
- AI in cancer detection
- Infection Control and Ventilation
- Pediatric Urology and Nephrology Studies
The University of Sydney
2016-2025
Westmead Hospital
2016-2025
RELX Group (Netherlands)
2024
Westmead Institute
2014-2024
University of Oxford
2019
Film Independent
2018
Queens College, CUNY
2018
Columbia University
2018
Hutt Hospital
2012
Wellington Hospital
2011
<b>1</b> ESGE recommends cold snare polypectomy (CSP) as the preferred technique for removal of diminutive polyps (size ≤ 5 mm). This has high rates complete resection, adequate tissue sampling histology, and low complication rates. (High quality evidence, strong recommendation.) <b>2</b> suggests CSP sessile 6 – 9 mm in size because its superior safety profile, although evidence comparing efficacy with hot (HSP) is lacking. (Moderate weak <b>3</b> HSP (with or without submucosal injection)...
<h3>Objective</h3> Wide-field endoscopic mucosal resection (WF-EMR) is an alternative to surgery for treatment of advanced colonic neoplasia up 120 mm in size, but has been criticised its potentially high recurrence rates. We aimed quantify at 4 months (early) and 16 (late) following successful WF-EMR identify risk factors clinical significance. <h3>Design</h3> Ongoing multicentre, prospective, intention-to-treat analysis sessile or laterally spreading lesions ≥20 size referred seven...
Perforation is the most serious complication associated with endoscopic mucosal resection (EMR). We propose a new classification for appearance and integrity of muscularis propria (MP) after EMR including various extents deep mural injury (DMI). Risk factors these injuries were analysed.Endoscopic images histological specimens consecutive patients undergoing colonic laterally spreading lesions ≥20 mm at large Australian tertiary referral endoscopy unit retrospectively analysed using our DMI...
<h3>Objective</h3> Endoscopic mucosal resection (EMR) is effective for large laterally spreading flat and sessile lesions (LSLs). Sessile serrated adenomas/polyps (SSA/Ps) are linked to the relative failure of colonoscopy prevent proximal colorectal cancer. We aimed examine technical success, adverse events recurrence following EMR SSA/Ps in comparison with conventional adenomas. <h3>Design</h3> Over 74 months till August 2014, prospective multicentre data LSLs ≥20 mm were analysed. A...
Background and aims Conventional hot snare endoscopic mucosal resection (H-EMR) is effective for the management of large (≥20 mm) non-pedunculated colon polyps (LNPCPs) however, electrocautery-related complications may incur significant morbidity. With a superior safety profile, cold EMR (C-EMR) LNPCPs an attractive alternative however evidence lacking. We conducted randomised trial to compare efficacy C-EMR H-EMR. Methods Flat, 15–50 mm adenomatous were prospectively enrolled randomly...
<h3>Objective</h3> The serrated neoplasia pathway accounts for up to 30% of all sporadic colorectal cancers (CRCs). Sessile adenomas/polyps (SSA/Ps) with cytological dysplasia (SSA/P-D) are a high-risk CRC precursor little existing data. We aimed describe the clinical and endoscopic predictors SSA/P-D high grade (HGD) or cancer. <h3>Design</h3> Prospective multicentre data SSA/Ps ≥20 mm referred treatment by mucosal resection (September 2008–July 2013) were analysed. Imaging lesion...
Abstract Background The SMSA (size, morphology, site, access) polyp scoring system is a method of stratifying the difficulty polypectomy through assessment four domains. aim this study was to evaluate ability predict critical outcomes endoscopic mucosal resection (EMR). Methods We retrospectively applied prospectively collected multicenter database large colonic laterally spreading lesions (LSLs) ≥ 20 mm referred for EMR. Standard inject-and-resect EMR procedures were performed. primary end...
Objective Residual or recurrent adenoma (RRA) after endoscopic mucosal resection (EMR) of large non-pedunculated colorectal polyps (LNPCPs) ≥20 mm is a major limitation. Data on outcomes the treatment recurrence are scarce, and no evidence-based standard exists. We investigated efficacy retreatment over time in prospective cohort. Design Over 139 months, detailed morphological histological data consecutive RRA detected EMR for single LNPCPs at one tertiary endoscopy centre were prospectively...
Non-lifting large non-pedunculated colorectal polyps (NL-LNPCPs) account for 15% of LNPCP and are effectively managed by Endoscopic Mucosal Resection with adjunctive Cold-forceps Avulsion adjuvant Snare-Tip soft coagulation (CAST). However, recurrence rates > 10% at surveillance colonoscopy is a significant limitation. We aimed to compare the outcomes CAST MTA versus alone NL-LNPCPs. Prospective observational data on consecutive patients NL-LNPCPs treated EMR single tertiary center was...
Letter to: Endoscopic submucosal dissection for proximal colonic lesions: An effective therapeutic optionEndosc Int Open 2025; 13(CP): DOI: 10.1055/a-2443-1609
<b>Background and study aims:</b> Endoscopic mucosal resection (EMR) of laterally spreading lesions (LSLs) involving the ileocecal valve (ICV) is technically demanding. Conventionally, these are considered too challenging for endoscopic therapy primarily managed surgically. The aims were to describe effectiveness, safety, outcomes following EMR LSLs at ICV. <b>Patients methods:</b> This was a single-center, prospective, observational, cohort performed an academic, tertiary referral center....
Cold snare polypectomy (CSP) is safe and effective for the removal of small adenomas (≤10 mm); however, reported incomplete resection rates (IRRs) vary. The optimal CSP technique, where a wide margin normal tissue resected around target lesion, design have both been hypothesized to reduce IRR after CSP. We sought investigate efficacy thin-wire versus thick-wire diameter on IRR, using standardized technique.This was an international multicenter parallel randomized trial with 17 endoscopists...