A5039944092- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Silk-based biomaterials and applications
- Hydrogels: synthesis, properties, applications
- Graphene and Nanomaterials Applications
- Orthopaedic implants and arthroplasty
- 3D Printing in Biomedical Research
- Carbon and Quantum Dots Applications
- Tissue Engineering and Regenerative Medicine
- Dental Implant Techniques and Outcomes
- Nanoparticle-Based Drug Delivery
- biodegradable polymer synthesis and properties
- Titanium Alloys Microstructure and Properties
- Wound Healing and Treatments
- Dental materials and restorations
- Additive Manufacturing and 3D Printing Technologies
- Advanced Drug Delivery Systems
- Polymer Surface Interaction Studies
- Advanced ceramic materials synthesis
- Nanocluster Synthesis and Applications
- Advanced Sensor and Energy Harvesting Materials
- Advanced materials and composites
- Periodontal Regeneration and Treatments
- Advanced biosensing and bioanalysis techniques
- Osteoarthritis Treatment and Mechanisms
Indian Institute of Technology Kharagpur
2016-2025
Sree Chitra Thirunal Institute for Medical Sciences and Technology
2022
Indira Gandhi Centre for Atomic Research
2013
Indian Institute of Technology Indore
2012
University of Bristol
2006-2008
University Of Bristol Dental Hospital
2006-2008
American Ceramic Society
2006
University of Birmingham
2005
In the present work, a multiple-stimuli-responsive hydrogel has been synthesized via polymerization of acrylamide (AAm) and N-hydroxy methyl (HMAm) on β-cyclodextrin (β-CD). The β-CD-g-(pAAm/pHMAm) exhibited various striking features like ultrahigh stretchability (>6000%), flexibility, stab resistivity, self-recoverability, electroresponsiveness, pressure-responsiveness, adhesiveness, high transparency (>90%). Besides, demonstrated enhanced biocompatibility, UV resistance, thermoresponsive...
Most of the nanoimaging tools like quantum dots and metallic nanoparticles are shown to have different levels cytotoxicity via various mechanisms. However carbon nanodots (CNDs) a new group ultra small nano structures (average 4–6 nm) which is potential candidate next generation optical imaging. Being carbonaceous in origin, CNDs possess excellent luminescence photostability with significantly less cytotoxicity. In present study, we synthesized nano-dots from date molasses by microwave...
A novel stimulus-sensitive covalently cross-linked hydrogel derived from dextrin, N-isopropylacrylamide, and N,N′-methylene bis(acrylamide) (c-Dxt/pNIPAm), has been synthesized via Michael type addition reaction for controlled drug release application. The chemical structure of c-Dxt/pNIPAm confirmed through Fourier transform infrared (FTIR) spectroscopy 1H 13C NMR spectral analyses. surface morphology the studied by field emission scanning electron microscopic (FE-SEM) environmental (E-SEM)...
Cementless fixation for orthopedic implants aims to obviate challenges associated with bone cement, providing long-term stability of prostheses after implantation. The application porous titanium and its alloy-based is emerging load-bearing applications due their high specific strength, low stiffness, corrosion resistance, superior osteoconductivity. In this study, coagulant-assisted foaming was utilized the fabrication Ti6Al4 V using egg-white foam. Samples three different porosities 68.3%,...
Nitrogen, sulfur, and phosphorous co-doped water-soluble carbon nanodots are synthesized from culinary waste onion peel powder (OPP) by a short microwave treatment. Onion Derived Carbon Nano Dots (OCND) that comprised hydrophilic group-decorated amorphous nano-dots exhibited bright, stable fluorescence at an excitation of 450 nm emission wavelength 520 along with free radical scavenging property. The OCND excellent stability different pH UV exposure. Although extracted polyphenols degraded...
Direct-write assembly allows rapid fabrication of complex three-dimensional (3D) architectures, such as scaffolds simulating anatomical shapes, avoiding the need for expensive lithographic masks. However, proper selection polymeric ink composition and tailor-made viscoelastic properties are critically important smooth deposition shape retention. Deposition only silk solution leads to frequent clogging due shear-induced β-sheet crystallization, whereas optimized property silk-gelatin blends...
We report on the synthesis and characterization of a novel hydrogel based dextrin grafted with poly(2-hydroxyethyl methacrylate) by embedding N,N′-methylene bis acrylamide (MBA) as cross linker, into polymeric network in presence potassium persulphate (KPS) initiator for colon specific delivery ornidazole. Various grades hydrogels [Dxt-g-p(HEMA)] have been synthesized altering reaction parameters best one optimized. The developed has characterized using FTIR spectra, 13C NMR elemental...
Herein, novel biodegradable, stimulus-responsive, chemically cross-linked and porous hydrogel has been synthesized to evaluate its applicability as an efficient carrier for sustained release of ornidazole ciprofloxacin. The (c-Dxt/pAA) developed from dextrin poly(acrylic acid) using N,N′-methylene bis(acrylamide) cross-linker via Michael-type addition reaction. With the variation reaction parameters, various c-Dxt/pAA hydrogels have optimize best one. characterized physicochemical...
Abstract Collagen, a major component of native extracellular matrix, has diverse biomedical applications. However, its application is limited due to lack cost‐effective production and risk disease transmission from bovine sources currently utilized. This study describes fabrication characterization nano/micro fibrous scaffolds utilizing collagen extracted fresh water fish origin. the first time origin was studied for their biocompatibility immunogenicity. The were fabricated through...
Nanohybrid hydrogels based on pristine graphene with enhanced toughness and dual responsive drug delivery feature is opening a new era for smart materials. Here are synthesized by in situ free radical polymerization where platelets the nanobuiliding blocks to withstand external stress shows reversible ductility. Such uniqueness mere reflection of rubber-like elasticity hydrogels. These nanobuilding serve also extensive physisorption which enhances physical crosslinking inside gel matrix....
Macroporous hydrogel monoliths having tailor-made features, conductivity, superstretchability, excellent biocompatibility, and biodegradability, have become the most nurtured field of interest in soft biomaterials. Green method assisted reduced graphene oxide has been inserted by situ free radical gelation into semi-IPN matrix to fabricate conducting hydrogel. Mechanical toughness implemented for graphene–polymer physisorption interactions with basal planes. Moreover, as-prepared 3D scaffold...
Synthesis of an injectable hydrogel using glycine and β-cyclodextrin for sustained drug release.
Abstract Laser surface remelting is a widely used method for modification of titanium and related alloys, particularly to enhance its workability in the biomedical industry through nitriding. The present work aims develop nitride over LPBF-processed Ti6Al4V substrate by introducing nitrogen environment build chamber during remelting. effects different laser power scan speeds were studied topography elemental changes remelted surface. result shows an increase roughness with selective...
A simple direct foaming and casting process using ovalbumin‐based aqueous slurries for fabricating ceramic metal foams is demonstrated. Foaming of the foam microstructure were seen to be a strong function slurry rheology. Setting with solids loading above 20 vol% was achieved by addition acid, which also prevented binder migration. Acid resulted in excessive shrinkage, causing cracking below vol%. Addition sucrose suppressed shrinkage leading defect‐free porosity exceeding 95%. Overall could...
In this study, a hierarchical nano/microfibrous chitosan/collagen scaffold that approximates structural and functional attributes of native extracellular matrix has been developed for applicability in skin tissue engineering. Scaffolds were produced by electrospinning chitosan followed imbibing collagen solution, freeze‐drying, subsequent cross‐linking two polymers. Scanning electron microscopy showed formation layered scaffolds with architechture. Physicochemical properties including...