A5014337178- Pain Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Vitamin D Research Studies
- Diet and metabolism studies
- Neuropeptides and Animal Physiology
- Stress Responses and Cortisol
- Neurotransmitter Receptor Influence on Behavior
- COVID-19 Clinical Research Studies
- Cannabis and Cannabinoid Research
- Saffron Plant Research Studies
- Attention Deficit Hyperactivity Disorder
- SARS-CoV-2 and COVID-19 Research
- Pharmacological Effects and Toxicity Studies
- Anesthesia and Pain Management
- Tryptophan and brain disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- MicroRNA in disease regulation
- Treatment of Major Depression
- Pharmacological Effects of Natural Compounds
- Diabetes and associated disorders
- Thallium and Germanium Studies
- Extracellular vesicles in disease
- Flavonoids in Medical Research
- Migraine and Headache Studies
- Regulation of Appetite and Obesity
Kashan University of Medical Sciences
2016-2025
Guilan University of Medical Sciences
2024
Semnan University of Medical Sciences
2022
Ahvaz Jundishapur University of Medical Sciences
2010
Tehran University of Medical Sciences
2006
University of Tehran
2005
This study determined the effects of a novel combination vitamin D and probiotic on metabolic clinical symptoms in chronic schizophrenia.This trial was conducted among 60 patients with schizophrenia to receive either 50,000 IU D3 every 2 weeks plus 8 × 109 CFU/day (n = 30) or placebo for 12 weeks.Vitamin co-supplementation associated significant improvement general (- 3.1 ± 4.7 vs. + 0.3 3.9, P 0.004) total PANSS scores 7.4 8.7 -1.9 7.5, 0.01). Vitamin also significantly increased...
Despite the abundance of skin substitutes in worldwide market, major hurdles developing more complex tissues include addition appendages and vascular networks as most important structure. The aim this research was a clinical feasibility study novel prevascularized grafts containing dermal epidermal layer using adipose stromal fraction (SVF)-derived endothelial cell population for network regeneration. Herein, we characterized hydrogel with emphasis on biological compatibility proliferation,...
Exosomes (EXOs) are naturally occurring nanosized lipid bilayers that can be efficiently used as a drug delivery system to carry small pharmaceutical, biological molecules and pass major barriers such the blood-brain barrier. It was hypothesized EXOs derived from human endometrial stem cells (hEnSCs-EXOs) utilized carrier enhance tumor-targeting drugs, especially for those have low solubility limited oral bioactivity. In this study, atorvastatin (Ato) loaded (AtoEXOs) prepared characterized...
Methadone maintenance treatment (MMT) might be associated with the symptoms of depression and anxiety, sleep disturbances sexual dysfunctions. This study was designed to determine effects crocin on psychological parameters in patients under MMT. Patients MMT were randomly allocated into two groups receive either 30 mg/day (2 plus tablet, 15 mg BID) (n = 25) or placebo tablets per day, 25), one hour after taking food, for 8 weeks. Psychological evaluated at baseline end trial related...
Opioid dependence is an increasing clinical and public health problem. Current pharmacotherapies have limited efficacy cause serious side effects. Increasing bodies of evidences suggest the neuropeptide, oxytocin (OT), as a potential treatment for drug abuse disorders. The current study was designed to evaluate effect OT on withdrawal, craving anxiety scores, cortisol dehydroepiandrosterone sulphate (DHEAS) blood level in heroin-dependent male patients. This randomized, double-blind...
Persian medicine has recommended clinical experiences and proper herbal remedies for prevention treatment of microbial infections respiratory diseases. An open‐label, randomized, controlled, multicenter trial was conducted at five hospitals in Tehran Isfahan provinces Iran on 358 hospitalized adult patients. A total 174 patients received standard care 184 (polyherbal decoction every 8 hr two capsules 12 hr) plus 7 days. The primary endpoint the duration hospital stay, secondary outcomes were...
The outbreak of Coronavirus disease 2019 (COVID‐19) has caused a global health crisis. Nevertheless, no antiviral treatment yet been proven effective for treating COVID‐19 and symptomatic supportive cares have the most common treatment. Therefore, present study was designed to evaluate effects propolis Hyoscyamus niger L. extract in patients with COVID‐19. This randomized clinical trial conducted on 50 cases referred Akhavan Sepehri Clinics, Kashan university medical sciences, Iran. Subjects...
Abstract This investigation was designed to determine the effect of melatonin supplementation on mental health parameters, metabolic and genetic profiles in patients under methadone maintenance treatment (MMT). randomized, double‐blind, placebo‐controlled, clinical trial conducted among 54 MMT. Participants were randomly allocated receive either 10 mg (2 capsules, 5 each) ( n = 26) or placebo 28) once a day, 1 hour before bedtime for 12 weeks. Melatonin significantly decreased Pittsburgh...
Background: Endometrium is recently introduced as an available source of mesenchymal stem cells (EnMSCs), which can be obtained without anesthesia and side effects. Regarding the issues complexities cell-based therapies, exosomes gain tremendous attention a novel tool for cell-free therapies. Although several clinical trials are established based on therapeutic potential EnMSCs, biological roles EnMSC-derived still unclear. Methods: The current study was conducted to investigate effects...
Patients under methadone maintenance treatment (MMT) programs are susceptible to several complications including metabolic and clinical disorders. This study was designed determine the effect of crocin supplementation on mental health parameters profiles in subjects MMT. The current randomized, double‐blind, placebo‐controlled, trial conducted among 53 patients MMT receive either 15 mg/day ( n = 26) or placebo 27) twice a day for 8 weeks. Crocin administration significantly decreased Beck...