A5012177536- Advanced Fluorescence Microscopy Techniques
- Optical Coherence Tomography Applications
- Photoacoustic and Ultrasonic Imaging
- Nonlinear Optical Materials Studies
- Integrated Circuits and Semiconductor Failure Analysis
- Analytical Chemistry and Sensors
- Nanofabrication and Lithography Techniques
- Extracellular vesicles in disease
- Electrochemical Analysis and Applications
- Mechanical and Optical Resonators
- Advancements in Transdermal Drug Delivery
- Machine Learning in Materials Science
- Ocular Surface and Contact Lens
- Near-Field Optical Microscopy
- Lower Extremity Biomechanics and Pathologies
- Contact Dermatitis and Allergies
- MicroRNA in disease regulation
- Neuroscience and Neural Engineering
- Cell Image Analysis Techniques
- Thermal properties of materials
- Anesthesia and Neurotoxicity Research
- Smart Materials for Construction
- Force Microscopy Techniques and Applications
- Advanced Sensor and Energy Harvesting Materials
- Nanopore and Nanochannel Transport Studies
Profactor (Austria)
2025
University of Applied Sciences Upper Austria
2019-2024
Austrian Cluster for Tissue Regeneration
2020-2021
Johannes Kepler University of Linz
2013-2020
Abstract Biomimetics is the interdisciplinary scientific field focused on study and imitation of biological systems, with aim solving complex technological problems. In this paper, we present a new bio-inspired design for microneedles (MNs) MN arrays, intended rapidly coating MNs drug/vaccine. The biomimetic approach consists in ornamenting lateral sides pyramidal structures inspired by external scent efferent systems some European true bugs, which facilitate directional liquid transport. To...
High-resolution imaging is essential for analysis of the steps and way stations cargo transport in
Interest in mesenchymal stem cell derived extracellular vesicles (MSC-EVs) as therapeutic agents has dramatically increased over the last decade. Current approaches to characterization and quality control of EV-based therapeutics include particle tracking techniques, Western blotting, advanced cytometry, but standardized methods are lacking. In this study, we established verified quartz crystal microbalance (QCM) highly sensitive label-free immunosensing technique for characterizing...
The fabrication of two- and three-dimensional scaffolds mimicking the extracellular matrix providing cell stimulation is high importance in biology material science. We show two new, biocompatible polymers, which can be 3D structured
Recently, 2D/3D direct laser writing has attracted increased attention due to its broad applications ranging from biomedical engineering aerospace. 3D nanolithography of water-soluble protein-based scaffolds have been envisioned provide a variety tunable properties. In this paper, we present functional photoresist with mechanical properties that is suitable for multiphoton lithography (MPL). Through the use methacrylated streptavidin or bovine serum albumin in combination polyethylene glycol...
The durability of piezoresistive sensor materials is a core prerequisite for their implementation in structural health monitoring systems. In this work, three were subjected to extensive cyclic tensile loadings, and behaviour was analysed before, after, during testing. To end, aluminium specimens coated with different industry-grade lacquers, then applied onto each specimen. Sensors made from carbon black displayed excellent linearity even after loading cycles (R2>0.88). A decline all...
Tracking of biological and physiological processes on the nanoscale is a central part growing field nanomedicine. Although atomic force microscopy (AFM) one most appropriate techniques in this area, investigations non-transparent fluids such as human blood are not possible with conventional AFMs due to limitations caused by optical readout. Here, we show promising approach based self-sensing cantilevers (SSC) replacement for readout AFM imaging. Piezo-resistors, form Wheatstone bridge,...
We show that multiphoton thiol–ene polymerized structures comprise unreacted thiol moieties, which can be used for postpolymerization gold metallization. Some of the groups located at surface are not involved in reactions and, therefore, serve as nucleation seeds synthesis ∼50 nm sized nanoislands. Additionally, we nanoislands immobilization fluorescent molecules. observed a significant enhancement fluorescence signal on nanoisland-functionalized polymer when compared to structured polymers...
We present a polarization-sensitive full-field optical coherence microscopy modality which is capable of simultaneously delivering depth resolved information on the reflectivity, retardation and axis orientation. In this way local birefringence, inherent stress–strain fields anisotropies can be visualized with high resolution, as exemplified for various technical material applications.
We illustrate the abilities of an advanced full-field optical coherence microscope (FF-OCM) setup for characterization technical materials with internal micro-structures and present this technique also dynamic process monitoring, as strain-stress tests. Additionally we briefly potential image processing in context chosen applications. Furthermore, contrast modification techniques based on Fourier plane filtering are discussed.
The microelectrode ion flux estimation (MIFE) is a powerful, non-invasive electrophysiological method for cellular membrane transport studies. Usually, the MIFE measurements are performed in tissue culture dish or directly with tissues (roots, parts of plants, and cell tissues). Here, we present transwell system that allows on monolayer. We introduce measurement window insert membrane, which provides direct access cells to media upper lower compartment cell-to-cell contact coculture....
We discuss balanced time-domain full-field optical coherence tomography (FF-OCT) realized in a Mach-Zehnder configuration. The detection scheme and spatial phase shifting allow single-shot acquisition reconstruction FF-OCT. Combined with 2D quadrature signal-based demodulation technique applying the Riesz transform, previously illustrated for dual-shot temporal FF-OCT, we demonstrate concept shifting. monitoring of dynamic processes by FF-OCT is enabled this approach. advantage consists...
This paper illustrates specific features and use of optical coherence tomography (OCT) in the raster-scanning comparison full field version this imaging technique. Cases for nondestructive testing are discussed alongside other application schemes. In particular monitoring time-dependent processes probing birefringent specimens considered here. context polymer birefringence mapping may often provide information about internal strain stress states. Recent results obtained with conventional OCT...
Abstract Interest in mesenchymal stem cell derived extracellular vesicles (MSC-EVs) as therapeutic agents has dramatically increased over the last decade. Preclinical studies show that MSC-EVs have anti-apoptotic and neuroprotective effects, boost wound healing, improve integration of allogeneic grafts through immunomodulation. Current approaches to characterization quality control EV-based therapeutics include particle tracking techniques, Western blotting, advanced cytometry, but...