A5000517114- Preterm Birth and Chorioamnionitis
- Global Maternal and Child Health
- Pregnancy-related medical research
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Pregnancy and preeclampsia studies
- Pelvic floor disorders treatments
- Uterine Myomas and Treatments
- Healthcare Policy and Management
- Healthcare Systems and Reforms
- Immunodeficiency and Autoimmune Disorders
- Reproductive tract infections research
- Cervical Cancer and HPV Research
- Blood groups and transfusion
- Parvovirus B19 Infection Studies
- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- Ectopic Pregnancy Diagnosis and Management
- Endometriosis Research and Treatment
- Neonatal Respiratory Health Research
- HIV, Drug Use, Sexual Risk
- Global Cancer Incidence and Screening
- Reproductive Health and Contraception
- Child and Adolescent Health
- Blood donation and transfusion practices
Nnamdi Azikiwe University
2010-2025
Nnamdi Azikiwe University Teaching Hospital
2014-2025
The study evaluated the pattern of severe maternal outcome, near miss indicators and associated patient healthcare factors at a private referral hospital in rural Nigeria.This was cross sectional conducted from September 2014 to August 2015 Madonna University Teaching Hospital Elele, Rivers State, Nigeria. Pregnant postpartum women were recruited for using Nigeria network proforma which adopted WHO proforma. We explored administrative, related medical delays. Statistical analysis done SPSS...
Abstract Purpose: To determine values of combinations interleukin-6 (IL-6)/cervical native insulin-like growth factor-binding protein-1 (IGFBP-1)/total IGFBP-1 (Premaquick©) in predicting spontaneous deliveries and exclusive preterm women with threatened labor. Methods: Women singleton pregnancies between gestation age (GA) 24 weeks 36 6 days labor were recruited during a prospective multicenter study. Premaquick© was positive when at least two three biomarkers positive. Sensitivity,...
Objectives: To determine the effectiveness of perineal massage during second stage labour in preventing trauma nulliparous women. Methods: A randomized control trial involving 104 women undergoing vaginal delivery. The participants were randomised into two arms (intervention-group 'A' and control-group 'B') a 1:1 ratio. intervention group had routine hands-on technique according to hospital protocol while received only technique. primary outcome measure was incidence tears delivery,...
Objectives To determine seroprevalence, seroconversion, and mother-to-child transmission (MTCT) rates for dual triplex infections of human immunodeficiency virus (HIV), hepatitis B (HBV), C (HCV) among pregnant women. Methods A multicentre prospective cohort study was conducted in six randomly selected tertiary hospitals from geopolitical zones Nigeria. Consenting participants were tested at recruitment followed-up till delivery. Retests performed delivery those who negative all three...
Background: Preeclampsia is a leading cause of maternal morbidity and mortality. Various predictive methods exist, but none are without flaws. Risk factors vary in different women at gestational ages; hence, investigating non-modifiable factors, such as ABO Rhesus blood groups, may aid prediction early detection preeclampsia. Objectives: This study aimed to evaluate the association between groups Design: was prospective cohort study. Methods: included singleton, normotensive, Rhesus-positive...
Abstract Aim To determine accuracy and costs of placental α‐microglobulin‐1 ( PAMG ‐1) test compared to standard clinical assessment SCA ) for diagnosing rupture membranes ROM ). Methods A multicenter double‐blind study consecutive women with symptoms signs in N namdi zikiwe U niversity T eaching H ospital, newi igeria E nugu, both south‐east using the ‐1 was done. diagnosed if two out three methods from (pooling, positive nitrazine or ferning) were present confirmed post‐delivery based on...
To compare the efficacy and safety of intravenous intramuscular oxytocin in preventing atonic primary postpartum haemorrhage third stage labour.
To investigate the prevalence of life-threatening complications related to pregnancies with abortive outcome and associated health service events performance in Nigerian public tertiary hospitals.Secondary analysis a nationwide cross-sectional study.Forty-two hospitals.Women admitted for pregnancy-related complications.All cases severe maternal outcomes (SMO: near-miss or death) due pregnancy (defined as spontaneous induced abortion, ectopic pregnancy) were prospectively identified over 1...
Objectives: To determine diagnostic performance of placental alpha-microglobulin-1 (PAMG-1) test compared to conventional clinical assessment (CCA) in women with prolonged pre-labour rupture membranes (PROM).Methods: A double-blind study symptoms and signs PROM Nnamdi Azikiwe University Teaching Hospital, Nnewi Nigeria Enugu, south-east using CCA for PAMG-1 was done. Women were included if their symptoms, or complaints suggestive more than 24 h duration. diagnosed two out three methods from...
Abstract Purpose: To determine the diagnostic accuracy of insulin-like growth factor binding protein-1/alpha fetoprotein (Amnioquick duo+ ® ) compared with traditional clinical assessment (TCA) nitrazine, ferning and pooling for diagnosis prelabor rupture membranes (PROM). Methods: A double-blinded, multicenter study was conducted between February 2015 August among pregnant women presenting symptoms or features suggestive PROM 24 42 weeks gestation. Confirmation done after delivery based on...
The aim of this study was to determine accuracy and response time duo insulin-like growth factor binding protein-1 (IGFBP-1)/alpha-fetoprotein (Amnioquick duo+) versus placental alpha-microglobulin-1 (PAMG-1) in diagnosing premature rupture membranes (PROM).A multicenter prospective conducted among women with features suggestive PROM between 24 42 gestational weeks (GW). confirmed post-delivery based on presence any two these criteria: delivery within 48 h 7 days, chorioamnionitis, overtly...
This study determined patterns of microbial isolates in genital tract women with preterm pre-labour rupture membranes (PPROM) compared cases without PPROM. Endocervical swabs confirmed diagnosis PPROM were examined microbiologically and blinded pattern gestational-age-matched controls. One hundred five microbiological results each for controls analysed. Positive cultures seen 79.05% versus 6.67% Streptococcus spp. (31.43%) was the commonest organism isolated (p < 0.001), while Candida...
Uterine leiomyoma is a common gynecological condition that negatively affects women's quality of life. Vitamin D plays an important role in tumor development and progression. However, clinical studies comparing serum vitamin levels between women with without uterine leiomyomas are limited inconclusive. This study aimed to compare leiomyomas. hospital-based case-control included 150 who visited clinic. The cases 75 leiomyoma, whereas the controls age-and parity-matched participants leiomyoma....
To compare Premaquick biomarkers (combined insulin-like growth-factor binding protein 1 and interleukin-6) cervical length measurement via transvaginal ultrasound for pre-induction evaluation at term among pregnant women.A randomized clinical trial of consenting women the Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria. The were equally into group (n = 36) 36). cervix was adjudged 'ripe' if test positive or trans-vaginal measured less than 28 mm. primary outcome measures...
Studies assessing the various modes of treatment for abortion and its associated complications remain relevant in generation data that will aid policy formulation management. This descriptive cross-sectional study was undertaken to determine common methods of, together with with, among healthcare practitioners south-eastern Nigeria. There were 230 males 207 females, a mean age 38.23 + 10.4 years. General accounted 214 (49.0%) respondents; nurses, 161 (36.8%); specialist doctors, 56 (12.8%);...
Background: Fetomaternal haemorrhage may occur during pregnancy or at delivery and lead to allo-immunization the D antigen if mother is Rhesus (Rh) negative baby Rh-positive. Objectives: To determine incidence, socio-demographic characteristics outcomes of Rh pregnant women in a Nigeria Tertiary health care institution. Methods: A review clinical records all Rh-negative women, managed Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, South-east between 1st January 2009 31st...