Rationale: Intensive care unit (ICU)-based randomized clinical trials (RCTs) among adult critically ill patients commonly fail to detect treatment benefits.Objectives: Appraise the rates of success, outcomes used, statistical power, and design characteristics published trials.Methods: One hundred forty-six ICU-based RCTs diagnostic, therapeutic, or process/systems interventions from January 2007 May 2013 in 16 high-impact general critical journals were studied.Measurement Main Results: Of...

Study Design. A retrospective cohort study. Objective. The aim of this study was to identify associations between abnormal coagulation profile and postoperative morbidity mortality in patients undergoing posterior lumbar fusion (PLF). Summary Background Data. literature suggests that is associated with complications, notably the need for blood transfusion. However, there little research directly addresses influence on complications following PLF. Methods. American College Surgeons National...

Background.— In contrast to migraine and tension‐type headache, the psychiatric comorbidities of cluster headache (CH) have not been well‐studied. Objective.— We assessed presence depression anxiety in groups episodic CH (ECH) chronic (CCH) patients compared with without anxiety. Methods.— Sociodemographics, comorbidities, selected features were ascertained from a clinic‐based sample cross‐sectional fashion January 2007 July 2010. Active using Patient Health Questionnaire (PHQ‐9) Generalized...

Study Design: This is a retrospective cohort study. Objective: To determine whether age, sex, and race have independent effects on sagittal pelvic parameters. Summary of Background Data: Pelvic parameters balance correlate with health-related quality life are important for patient assessment surgical planning. Age, 3 unalterable factors that may influence morphology. Methods: We conducted review consecutive adult patients who presented to our radiology practice between 2010 2015 had...

Study Design. Retrospective clinical study of individuals with osteogenesis imperfecta (OI). Objective. To assess the relationship between severity scoliosis and pulmonary function, to restrictive lung disease self-reported quality life in OI. Summary Background Data. OI is a heritable connective tissue disorder characterized by osteopenia predisposition fracture. Respiratory insufficiency leading cause mortality. Literature on function this population has shown negative correlation...

Background: Achilles tendon rupture (ATR) is a common injury with growing incidence rate. Treatment either operative or nonoperative. However, evidence lacking on the cost comparison between these modalities. The objective of this study to investigate differences and nonoperative treatment ATR using large national database. Methods: Patients who received for an were abstracted from commercial insurance claims database, Marketscan Commercial Claims Encounters Database (n = 100 825) divided...

A retrospective analysis.The aim of our study was to analyze the association Area Deprivation Index (ADI) with utilization and costs elective anterior cervical discectomy fusion (ACDF) surgery.ADI, a comprehensive neighborhood-level measure socioeconomic disadvantage, has been shown be associated worse perioperative outcomes in variety surgical settings.The Maryland Health Services Cost Review Commission Database queried identify patients who underwent primary ACDF between 2013 2020 state....

Objective The aim of this study was to compare all-cause reoperation rates and costs in nonelderly patients treated with anterior cervical discectomy fusion (ACDF) structural allograft versus synthetic cages for degenerative pathology. Methods We queried a private claims database identify adult (≤ 65 years) who underwent single-level ACDF hospital setting using either or cage (polyetheretherketone, metal, hybrid device), from 2010 2016. rate reoperations at 2 years were compared between the...

Case series/systematic review.To report on patients undergoing posterior cervical fusion for symptomatic pseudarthrosis following anterior discectomy and (ACDF), to assess outcomes reporting in the literature.Patients instrumented after primary ACDF from 2013 2018 by a single surgeon were reviewed consecutively. Neck Disability Index (NDI) visual analogue scale (VAS) arm/neck recorded at preoperative, 6-month, 1-year time points. A systematic review of literature was performed, recorded.NDI...

Background: Primary Achilles tendon repair (ATR) can be performed in ambulatory surgery centers (ASCs) or hospitals. We compared costs and complication rates of ATR these settings. Methods: retrospectively queried the electronic medical record our academic health system identified 97 adults who underwent primary from 2015 to 2021. Variables were between patients treated at ASCs vs those continuous variables with Wilcoxon rank-sum tests categorical χ 2 tests. used an α 0.05. Multivariable...

Retrospective analysis of prospectively collected data.The aim this study was to determine the ability abnormal coagulation profile predict adverse events following posterior cervical laminectomy and fusion (PCLF).PCLF is an increasingly common procedure used treat a variety traumatic degenerative spinal conditions. Abnormal associated with postoperative events, including blood transfusion. There paucity literature that specifically addresses relationship between complications PCLF.ACS-NSQIP...

Retrospective cohort study.To determine if membership in a high-risk subgroup is predictive of morbidity and mortality following anterior lumbar fusion (ALF).The American College Surgeons National Surgical Quality Improvement Program database was utilized to identify patients undergoing ALF between 2010 2014. Multivariate analysis as an independent predictor postoperative complications.Members the elderly (≥65 years) (OR = 1.3, P .02) non-Caucasian (black, Hispanic, other) 1.7, < .0001)...

Study Design. A retrospective analysis of prospectively collected data. Objective. The aim this study was to determine the ability Revised Cardiac Risk Index (RCRI) predict adverse cardiac events following posterior lumbar decompression (PLD). Summary Background Data. PLD is an increasingly common procedure used treat a variety degenerative spinal conditions. RCRI risk for noncardiac surgery. There paucity literature that directly addresses relationship between and outcomes PLD,...

In Brief Study Design. Prospective cohort study. Objective. To examine preoperative urinary cross-linked n-telopeptide (uNTx) and assess for association with fusion rates in patients undergoing single multi-level anterior cervical decompression (ACDF). Summary of Background Data. Although high have been reported ACDF, the risk pseudarthrosis remains substantial. An established marker bone turnover, uNTx may prove useful as a predictor fusion. Methods. Patients primary ACDF allograft/plating...

Study Design. Retrospective cohort study. Objective. The objective of this study was to characterize the costs associated with American Society Anesthesiologists (ASA) class, and determine extent which ASA status is a predictor increased cost LOS following lumbar laminectomy fusion (LLF). Summary Background Data. Spinal accounts for highest hospital any surgical procedure performed in United States, (American Anesthesiologists) known risk factor length stay (LOS) orthopedic literature. There...

<h3>Background</h3> Adult spinal deformity (ASD) is a disorder characterized by abnormal curvature of the spine resulting from progressive degeneration elements. Although operative intervention for ASD commonplace, it associated with several complications, including proximal junctional kyphosis (PJK) and failure (PJF). The objective this review to outline role fixation in preventing PJK PJF. <h3>Methods</h3> We conducted literature search using Embase, Scopus, Web Science, CINHAL, Cochrane...

The purpose of this study is to examine the effect hypoalbuminemia (HA) on sentinel adverse events after total shoulder arthroplasty (TSA).Patients who underwent primary TSA from 2015-2018 were collected National Surgical Quality Improvement Program (NSQIP) database. Patients with HA (serum albumin < 3.5 g/dL) compared patients normal serum albumin. A probit regression model was used estimate a propensity score. Logistic performed evaluate surgery.A 4,337 included, 8.2% had HA. higher rates...