A5089927041- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Ocular Infections and Treatments
- Ocular Disorders and Treatments
- Glaucoma and retinal disorders
- Ocular Diseases and Behçet’s Syndrome
- Infectious Diseases and Mycology
- Drug-Induced Adverse Reactions
- Contact Dermatitis and Allergies
- Mast cells and histamine
- Herpesvirus Infections and Treatments
- Acne and Rosacea Treatments and Effects
- Oral and Maxillofacial Pathology
- Urticaria and Related Conditions
- Mycobacterium research and diagnosis
- Sphingolipid Metabolism and Signaling
- Antifungal resistance and susceptibility
- Myxozoan Parasites in Aquatic Species
- Retinal and Optic Conditions
- Impact of AI and Big Data on Business and Society
- Cytomegalovirus and herpesvirus research
- Technology and Data Analysis
- Nasal Surgery and Airway Studies
- Traumatic Ocular and Foreign Body Injuries
Sankara Nethralaya
2016-2025
Medical Research Foundation
2024
Creative Commons
2022-2023
Apollo Hospitals
2023
Nethradhama Superspeciality Eye Hospital
2023
Apollo Hospitals
2022
Christie's
2015-2020
Institute of Medical Sciences
2019
D.Y. Patil University
2016-2017
Madras Diabetes Research Foundation
2015
To analyse the clinical and demographic profiles of patients with vernal keratoconjunctivitis (VKC) propose a grading for VKC based on corneal status symptom periodicity rather than disease activity. Retrospective observational study from January 2015 to 2020 in India. was past/present signs frequency symptoms The electronic medical records were screened details diagnosed by cornea specialists recorded analysed. 1096 mean age onset 7.05±5.3 8.39% having adult Symptoms included; itching...
Purpose: To report the long-term outcome of corneal collagen cross-linking (CXL) for progressive keratoconus in pediatric patients. Methods: “Epithelium-off” CXL was performed eyes with keratoconus. Spectacle-corrected distance visual acuity (CDVA), retinoscopy, topography, and tomography were documented preoperatively postoperatively at 3 months, 6 1 year, annually thereafter. Results: A total 377 336 patients aged 8 to 18 years underwent CXL. Of these, 194 had a follow-up beyond 2 up 6.7...
Dry eye syndrome (DES) is a complex, multifactorial, immune-associated disorder of the tear and ocular surface. DES with high prevalence world over needs identification potential biomarkers so as to understand not only disease mechanism but also identify drug targets. In this study we looked for differentially expressed proteins in samples arrive at characteristic biomarkers. As part prospective case-control study, specimen were collected using Schirmer strips from 129 dry cases 73 age...
Purpose To report the clinical profile and role of perioperative adjunctive measures to reduce risk recurrence in Pythium insidiosum keratitis. Methods Retrospective analysis 10 eyes patients with P. Diagnosis was confirmed by PCR DNA sequencing. Results 7out were from urban locales, none had any obvious history injury vegetative matter being treated for fungal 6 presented central full thickness infiltrates subepithelial superficial stromal radiating a reticular pattern. Corneal scraping all...
Background To study the tear cytokine and conjunctival oral mucosal marker profile in chronic ocular Stevens-Johnson syndrome (SJS) their alteration following mucous membrane grafting (MMG) for lid margin keratinisation (LMK). Methods In a 1-year prospective study, SJS cases (n=25) age-matched/sex-matched healthy controls were recruited. Tear specimen (Schirmer’s strip), imprints collected from pre-MMG post-MMG (at first follow-up, n=17). cytokines profiled using 27-bioplex array....
To analyse the outcome of allo simple limbal epithelial transplantation (alloSLET) in eyes early stage following ocular chemical injury to achieve rapid epithelialisation.Records 18 17 patients who underwent alloSLET between April 2013 and Jan 2016 were analysed retrospectively. Patients with grade 4 or worse Dua's classification for injury, presented within a month non-healing defect since despite earlier medical surgical interventions, included study. The time epithelialisation was primary...
Purpose To report clinical profile and compare management options for Pythium keratitis. Method Retrospective interventional study of 46 patients diagnosed as keratitis by PCR DNA sequencing from January 2014 to July 2017. Interventions were categorised into medical (MM) (topical azithromycin linezolid with oral at presentation), surgery (S) (therapeutic penetrating keratoplasty, TPK), surgical adjunct (SA) (cryotherapy±alcohol TPK) (MA) (MM after TPK). Results Primary treatment included MM...
Abstract Tear proteomics, by 2‐DE, can give a fingerprint of the protein profile, which is well suited in clinical proteomics for biomarker identification and diagnostics. The mode tear collection influence representation proteins therefore it important to use appropriate method. In this study, capillary Schirmer was done healthy controls method validated dry eye syndrome conditions. 2‐D PAGE normal performed using pH 3–10 linear IPG strips followed 13% SDS‐PAGE. spot intensity analyzed PD...
To highlight and compare the outcomes of management for ocular sequelae Stevens-Johnson syndrome (SJS) over 25 years in a tertiary eye care institute.A retrospective chart review 798 eyes 399 patients with SJS evaluated between January 1990 December 2004 (group I) 847 517 2005 2014 II) was done. The primary secondary outcome measures were change best-corrected visual acuity (BCVA) an improvement symptoms surface status, respectively. groups subdivided into procedures stabilization (A)...
Ocular surface diseases are a group of complex conditions that often arise from multifactorial etiologies, involving various pathophysiological mechanisms may overlap with systemic diseases.[1] The intricacies these frequently require multidisciplinary approach to diagnosis and treatment, as affect the ocular have implications. Consequently, collaboration among specialists diverse fields—such ophthalmology, immunology, rheumatology, dermatology, allergy—is not just beneficial but essential....
To analyze the clinical profile of vernal keratoconjunctivitis (VKC) and its response to treatment in human immunodeficiency virus (HIV) patients relation with CD4 counts. This study is a retrospective observational case series HIV VKC. Thirteen presented VKC, 69.2% having severe-grade Median age onset VKC was 5 years children 31.5 adults. Seventy percent had drop counts at The duration between diagnosis statistically less adults than children. Eleven were on highly active antiretroviral...
To investigate gender differences in childhood- and adult-onset vernal keratoconjunctivitis (VKC), as well the variations between these onset groups. This was a retrospective, observational study (Jan 2015-Dec 2020). Electronic medical records of VKC patients managed by cornea specialists were analyzed based on their age (<16 years for childhood [C-VKC], >16 adult [A-VKC]) gender. Out 1018 patients, 931 had 87 onset. Both groups showed male predominance; however, it slightly less A-VKC, with...