P. Clément

ORCID: 0000-0003-4524-7165
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About
Contact & Profiles
Research Areas
  • Sexual function and dysfunction studies
  • Hormonal and reproductive studies
  • Urinary Bladder and Prostate Research
  • Social Sciences and Governance
  • Trauma Management and Diagnosis
  • Hypothalamic control of reproductive hormones
  • Aging, Elder Care, and Social Issues
  • Traumatic Ocular and Foreign Body Injuries
  • Neuroendocrine regulation and behavior
  • Salivary Gland Tumors Diagnosis and Treatment
  • Neuropeptides and Animal Physiology
  • Meningioma and schwannoma management
  • Neuroscience of respiration and sleep
  • Spinal Cord Injury Research
  • Facial Nerve Paralysis Treatment and Research
  • Head and Neck Cancer Studies
  • Disaster Response and Management
  • Peroxisome Proliferator-Activated Receptors
  • Cancer Diagnosis and Treatment
  • Tracheal and airway disorders
  • Airway Management and Intubation Techniques
  • Infectious Diseases and Tuberculosis
  • Nitric Oxide and Endothelin Effects
  • Sexuality, Behavior, and Technology
  • Sleep and Wakefulness Research

Florida State University
2023

Hôpital d'instruction des Armées Percy
2001-2021

Laboratoire de Neurosciences Cognitives
2018-2020

Centre National de la Recherche Scientifique
2005-2020

Université de Versailles Saint-Quentin-en-Yvelines
2012-2019

SKF (France)
2019

Centre Hospitalier Universitaire de Tours
2007-2019

Aix-Marseille Université
2013-2018

Inserm
2004-2017

Institut de Neurophysiopathologie
2014

Ejaculation is the final stage of coitus in mammalian male and results expulsion sperm out urethral meatus. Two successive phases, emission expulsion, can be distinguished during ejaculatory response. Normal anterograde ejaculation requires close coordination sympathetic, parasympathetic, somatic components commanding different peripheral anatomical structures (accessory sexual glands, ducti, striated muscles) involved ejaculation. The efferent pathways innervating these drive motor outputs...

10.1080/10532528.2005.10559833 article EN Annual Review of Sex Research 2005-03-01

A spinal ejaculation generator (SEG) has been identified in the rat with lumbar galaninergic interneurons playing a pivotal role (Science 2002;297:1566-1569). The aim was to evidence SEG humans.Spatial distribution of neurons studied postmortem cord segments 6 men and compared that women for evidencing sexual dimorphism. Based on segmental neurons, ability penile vibratory stimulation (PVS) elicit when concerned were injured 384 patients clinically complete injury (SCI) consequent...

10.1002/ana.24819 article EN Annals of Neurology 2016-12-05

The involvement of the neuropeptide oxytocin in control male sexual responses is documented although its exact mechanisms action, and especially site(s) are not fully delineated. In order to clarify this issue, we tested effects a peptide antagonist delivered through different routes on elicited, anaesthetized rats, by i.c.v. 7-hydroxy-2-(di-N-propylamino) tetralin (7-OH-DPAT), dopamine agonist, preferentially active D3 receptors.Seminal vesicle pressure (SVP) bulbospongiosus muscle (BS)...

10.1038/bjp.2008.176 article EN British Journal of Pharmacology 2008-05-12

Background and Purpose Oxytocin ( OT ) plays a major role in the control of male sexual responses. Notably, blockade receptors has been reported to inhibit ejaculation animals. The study aimed investigate action highly selective, non‐peptide antagonist GSK 557296 model pharmacologically induced anaesthetized rats. site was assessed by investigating different delivery routes for this compound. Experimental Approach Urethane‐anaesthetized W istar rats were implanted with cerebral ventricle...

10.1111/bph.12198 article EN British Journal of Pharmacology 2013-03-27

The mechanism of action by which 8-hydroxy-2-(di-<i>N</i>-propylamino)tetralin (8-OH-DPAT) facilitates ejaculation in conscious rats is not clearly established. serotonin (5-HT) 1A agonist 8-OH-DPAT may actually act on cerebral dopaminergic receptors to exert its proejaculatory effect. present work was undertaken clarify this issue testing various compounds i.c.v. delivered an experimental model the expulsion phase anesthetized Wistar rats. Intracerebroventricular delivery dose-dependently...

10.1124/jpet.105.092411 article EN Journal of Pharmacology and Experimental Therapeutics 2005-10-12

10.1016/j.anorl.2010.12.008 article EN publisher-specific-oa European Annals of Otorhinolaryngology Head and Neck Diseases 2011-06-03

Low-intensity extracorporeal shock wave therapy (Li-ESWT) has been reported to improve erectile function in patients with moderate-to-severe dysfunction (ED) or even convert phosphodiesterase type 5 inhibitors nonresponders responders. ED is highly prevalent hypertensive patients. The effect of Li-ESWT on an animal model hypertension-associated not reported.To investigate the and provide plausible mechanisms action local penile erection.Spontaneously rats (SHRs) active group (n = 13)...

10.1016/j.esxm.2019.08.006 article EN cc-by-nc-nd Sexual Medicine 2019-09-21
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