Sílvio K. Hirota

ORCID: 0000-0003-4527-8893
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About
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Research Areas
  • Oral Health Pathology and Treatment
  • Salivary Gland Tumors Diagnosis and Treatment
  • Oral and gingival health research
  • Oral and Maxillofacial Pathology
  • Head and Neck Cancer Studies
  • Tumors and Oncological Cases
  • Salivary Gland Disorders and Functions
  • Autoimmune and Inflammatory Disorders
  • Genital Health and Disease
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Autoimmune Bullous Skin Diseases
  • Cancer and Skin Lesions
  • Acupuncture Treatment Research Studies
  • Geography and Environmental Studies
  • Hedgehog Signaling Pathway Studies
  • Nail Diseases and Treatments
  • Cardiac tumors and thrombi
  • Histiocytic Disorders and Treatments
  • Ear and Head Tumors
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Cell Adhesion Molecules Research

Universidade de São Paulo
2006-2022

Universidade Brasil
2011

This study aimed to evaluate the efficacy of systemic drugs thalidomide, dapsone, colchicine, and pentoxifylline in treatment severe manifestations RAS.An open, 4-year clinical trial was carried out for 21 consecutive patients with RAS. Initially, were given a 2-week course prednisone bring them baseline status. Simultaneously, one four test assigned each patient be taken period 6 months. During trial, switched other three whenever side effects or lack satisfactory results occurred, 6-month...

10.1590/s1807-59322009000300008 article EN cc-by-nc Clinics 2009-03-01

O carcinoma epidermóide constitui a neoplasia maligna mais comum da boca, afetando principalmente indivíduos com de 50 anos. Sua ocorrência em jovens, idade inferior 40 anos, é rara (1 6% dos casos). Descreve-se um caso acometendo dorso e borda língua, classificado como T2N1M0 (estádio III), paciente do sexo feminino, leucoderma, 25 não-fumante não-etilista. A apresentação inicial era ulceração profunda dor intensa. Fatores predisponentes locais gerais, diagnóstico diferencial prognóstico...

10.1590/s0365-05962006000300007 article PT cc-by Anais Brasileiros de Dermatologia 2006-06-01

As reações liquenoides por drogas são mais comuns na pele, mas também podem ocorrer mucosa bucal. Estas lesões de difícil diagnóstico causa sua semelhança clínica com às do líquen plano oral idiopático. O presente artigo relata um caso reação liquenoide em bucal, associado ao uso carbamazepina, no qual o processo é enfatizado

10.1590/s0365-05962011000700040 article PT cc-by Anais Brasileiros de Dermatologia 2011-08-01

Considering previous data from our clinic, as had consistently demonstrated a significant number of OLP patients also reporting thyroid disease (Hashimoto's thyroiditis, in particular), the present study investigated prevalence with autoimmune disease, including Hashimoto's thyroiditis and Graves' disease.

10.1111/odi.13339 article EN Oral Diseases 2020-04-04

A male white patient aged 41 years was referred to the Stomatology Unit with a histopathological diagnosis of hyperplastic candidosis modera-te dysplasia on palate. The clinical examination showed plaque measuring about 2 cm in diameter, an erythematous halo, not removable by scraping (Fig. 1a). Also there atrophic area over which shaped similarly palatal lesion, dorsum tongue, suggested as-sociated median rhomboid glossitis 1b). Cytology and PAS staining con-firmed presence Candida...

10.1590/s1808-86942010000100023 article EN cc-by Brazilian Journal of Otorhinolaryngology 2010-02-01

There is conflicting evidence as to whether oral lichen planus (OLP) can undergo malignant transformation into squamous cell carcinoma (OSCC). This study aimed address this issue by analyzing a sample of Brazilian patients with either OLP or OSCC. Patients and Methods. was conducted in São Paulo, the world's fourth-largest city population. Two groups were analyzed. The group consisted 370 patients, while OSCC 154 patients. followed up for 21 years monitor clinical benefits from management...

10.1155/2022/5937540 article EN cc-by Dermatology Research and Practice 2022-01-01

This study was aimed at assessing the quality of life in patients submitted to surgical treatment for minor salivary gland neoplasms (MSGN). Twelve (10 women and 2 men, mean age: 49.4 years) with histopathologic diagnosis pleomorphic adenoma (PA, 3 cases), polymorphous low-grade adenocarcinoma (PLGA, cystic adenoid carcinoma (CAC, 4 muco-epidermoid (MEC, cases) were evaluated. All them treated by excision; CAC received radiotherapy as well. The evaluated through a self-administered...

10.1590/s1806-83242007000400016 article EN cc-by Brazilian Oral Research 2007-11-28

AbstractThis article reports a case in which patient, an adult black male, was diagnosed as having sialadenosis of idiopathic type, since clinical, computed tomography and laboratory examinations did not disclose any other abnormalities that could be associated with the glandular swelling. As this condition is quite harmless, requiring no intervention, unless for aesthetic reason, patient dismissed, being monitored sporadically. But after 8 months first consultation, advanced esophageal...

10.11606/issn.2357-8041.clrd.2015.108054 article EN cc-by-nc-sa Clinical and Laboratorial Research in Dentistry 2015-12-26

<p class="abstract">This article reports a case of oral lichenoid contact reaction (OLCR) in which bilateral lesion involving the buccal mucosa was observed. Its relevance lies on that lesions could be misdiagnosed as an leukoplakia, since they showed typical feature homogeneous white plaque; however, fortunately, this misjudgement spared because one lesions, right-buccal side, direct with amalgam filling. Hence, suspicion mucosal made and patient successfully treated by replacement....

10.18203/issn.2455-4529.intjresdermatol20195685 article EN International Journal of Research in Dermatology 2019-12-23
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