A5030143384- Frailty in Older Adults
- Nutrition and Health in Aging
- Hip and Femur Fractures
- Cardiac, Anesthesia and Surgical Outcomes
- Aging, Health, and Disability
- Geriatric Care and Nursing Homes
- Health Systems, Economic Evaluations, Quality of Life
- Intensive Care Unit Cognitive Disorders
- Chronic Disease Management Strategies
- Long-Term Effects of COVID-19
- Balance, Gait, and Falls Prevention
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac Health and Mental Health
- Stroke Rehabilitation and Recovery
- Cardiovascular and exercise physiology
- COVID-19 Clinical Research Studies
- Pelvic and Acetabular Injuries
- Bone health and osteoporosis research
- Vitamin D Research Studies
- COVID-19 and Mental Health
- Emergency and Acute Care Studies
- Aging and Gerontology Research
- Vitamin C and Antioxidants Research
- COVID-19 and healthcare impacts
- Enhanced Recovery After Surgery
Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable
2020-2025
Valencia Catholic University Saint Vincent Martyr
2014-2025
Hospital de La Ribera
2016-2025
Centro de Investigación Biomédica en Red de Salud Mental
2023
Universitat de València
2016-2022
Instituto de Salud Carlos III
2021
Centro de Investigación Biomédica en Red
2021
Sociedad Española de Reumatología
2020
Université Paris-Sud
2020
Hamad Medical Corporation
2019
Background: Malnutrition increases worse outcomes during hospital admission for elective colorectal cancer (CRC) surgery in older adults. Methods: This work was designed an observational, monocentric, case-control study nested a cohort of patients undergoing CRC disease at the Hospital Universitario de la Ribera (HULR) (Alzira, Valencia, Spain) between 2011 and 2019. The considered with CONUT score range moderate to severe malnutrition (>4 points), control normal nutritional situations or...
Delaying the transition from minimal cognitive impairment to Alzheimer's dementia is a major concern in disease (AD) therapeutics. Pathological signs of AD occur years before onset clinical dementia. Thus, long-term therapeutic approaches, with safe, minimally invasive, and yet effective substances are recommended. There need develop new drugs delay We have taken nutritional supplement approach genistein, chemically defined polyphenol that acts by multimodal specific mechanisms. Our group...
Hip fractures are associated with high levels of co-morbidity and mortality. Orthogeriatric units have been shown to be effective respect functional recovery mortality reduction. The aim this study is document the natural history early multidisciplinary intervention in elderly patients hip establish prognostic factors walking ability after discharge.This observational, retrospective was performed an orthogeriatric care unit on aged >70 years a diagnosis fracture between 2004 2008. This...
Aim To identify how the severity of dementia influences functional recovery and mortality in elderly patients hospitalized for hip fracture. Methods An observational retrospective study 1258 aged older than 69 years diagnosed with fracture who received care within an orthogeriatrics unit from 2004 to 2008 was carried out. During a 12‐month follow‐up period, outcomes were measured. Results Dementia present 383 (28.1%) patients: it mild 183 (48%), moderate 102 (26.5%) severe 98 (25.5%)....
The development of animal models to study human frailty is important test interventions be translated the clinical practice. aim this work was develop a score for in experimental animals based phenotype. We also tested effect physical inactivity as determined by our score. Male C57Bl/6J mice, individually caged, were randomly assigned one two groups: sedentary (inactive) or spontaneous wheel-runners. compared versus active lifestyle terms evaluating criteria used humans: unintentional weight...
The frailty syndrome increases the morbidity/mortality in older adults, and several studies have shown a higher prevalence of this patients with Chronic Obstructive Pulmonary Disease (COPD). aim study was to identify characteristics frail COPD define new phenotype called "COPD-frail." We conducted cross-sectional cohort stable COPD, classified as either frail, pre-frail, or non-frail. Sociodemographic, clinical, biochemical variables were compared between three groups patients. included 127...
The aim of this study was to determine whether the inclusion older patients undergoing elective colorectal cancer resection in Enhanced Recovery After Surgery (ERAS®) programme could improve clinical outcomes during hospital admission.A before-and-after ≥70-year-old electively admitted for designed. In total, 213 were included ERAS® group, and 158 control group.The average age 77.9 years old (SD 5.31) 57.14% them men, with a Charlson Index score 3.42 3.32). group presented lower transfusion...
In older adults, the psychological impact and effects related to loss of functional capacity are directly perceived quality life (QOL). The predictors better QOL increased physical activity, lower prevalence overweight, cases depression, rate reported alcohol abuse. On contrary, decreased female gender, comorbidity, deficient nutritional condition, polypharmacy, mobility, depression dependency, poor economic conditions, social isolation loneliness. Furthermore, in adults is more dependent on...