A5001508789- Bone Tissue Engineering Materials
- Antifungal resistance and susceptibility
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
- Nanoplatforms for cancer theranostics
- Antimicrobial Peptides and Activities
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Laser-Ablation Synthesis of Nanoparticles
- Urinary Tract Infections Management
- Bone Metabolism and Diseases
- Calcium Carbonate Crystallization and Inhibition
- Dental materials and restorations
- Fungal Infections and Studies
- Orthopedic Infections and Treatments
- Essential Oils and Antimicrobial Activity
- Advanced Drug Delivery Systems
- Pneumocystis jirovecii pneumonia detection and treatment
- Dental Implant Techniques and Outcomes
- Bacteriophages and microbial interactions
- Aquaculture disease management and microbiota
- Orthopaedic implants and arthroplasty
Università Cattolica del Sacro Cuore
2023-2025
Candida parapsilosis is the major non-C. albicans species involved in colonization of central venous catheters, causing bloodstream infections. Biofilm formation on medical devices considered one main causes healthcare-associated infections and represents a global public health problem. In this context, development new nanomaterials that exhibit anti-adhesive anti-biofilm properties for coating crucial. work, we aimed to characterize antimicrobial activity two different coated-surfaces,...
Invasive fungal diseases are a significant threat in immunocompromised patients, underscoring the need for rapid and accurate diagnostics. This study describes development validation of real-time PCR-based laboratory-developed assay (LDA) on Panther Fusion system simultaneous detection Aspergillus fumigatus (AF) Pneumocystis jirovecii (PJ) bronchoalveolar lavage fluid (BALF) samples. The was evaluated using 239 clinical BALF samples, including cases confirmed positive AF or PJ by reference...
The global diffusion of antibiotic resistance poses a severe threat to public health. Addressing antibiotic-resistant infections requires innovative approaches, such as antibacterial nanostructured surfaces (ANSs). These surfaces, featuring ordered arrays nanostructures, exhibit the ability kill bacteria upon contact. However, most currently developed ANSs utilize bioinert materials, lacking bioactivity crucial for promoting tissue regeneration, particularly in context bone infections. This...
Introduction This study investigated the interaction with membrane mimetic systems (LUVs), bacterial membranes, CD spectra, and bactericidal activity of two designed trematocine mutants, named Trem-HK Trem-HSK. Mutants were constructed from scaffold Trematocine (Trem), a natural 22-amino acid AMP Antarctic fish Trematomus bernacchii , aiming to increase their positive charge. Methods The selectivity AMPs towards membranes was improved compared Trematocine, verified by different LUVs...
The increasing resistance of bacteria to conventional antibiotics represents a severe global emergency for human health. broad-spectrum antibacterial activity silver has been known long time, and at the nanoscale shows enhanced activity. This prompted research into development silver-based nanomaterials applications in clinical settings. In this work, synthesis three different nanoparticles (AgNPs) hybrids using both organic inorganic supports with intrinsic properties is described. tuning...
: The International Organization for Standardization (ISO) 20776-2:2021, which replaces ISO 20776-2:2007, focuses solely on the performance of antimicrobial susceptibility testing (AST) assays, emphasizing 20776-1 broth microdilution method as reference standard. Consequently, categorical agreement (CA) and associated errors should not be applied. We verified Vitek Reveal AST assay according to both 20776-2:2021 20776-2:2007 criteria.
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