A5060065580- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Esophageal Cancer Research and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Cancer, Hypoxia, and Metabolism
- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
- Multiple and Secondary Primary Cancers
- Colorectal and Anal Carcinomas
- Lung Cancer Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Pancreatic and Hepatic Oncology Research
- Medical Imaging Techniques and Applications
- Photodynamic Therapy Research Studies
- Medical Imaging and Pathology Studies
- Esophageal and GI Pathology
- Advances in Oncology and Radiotherapy
- Radiation Dose and Imaging
- Metabolomics and Mass Spectrometry Studies
- Head and Neck Cancer Studies
- Cerebral Venous Sinus Thrombosis
- Digital Imaging in Medicine
National Cancer Center Hospital East
2022-2025
The Japanese Society of Gastroenterological Surgery
2024
Iwate Medical University
2024
Onomichi General Hospital
2024
Hiroshima University
2024
Juntendo University
2023
Abstract Oxygen saturation imaging is a new technology that determines biological features from the perspective of oxygen concentration. Therefore, this exploratory study aimed to evaluate implications and further assess tumor heterogeneity in gastric cancer. Biopsy samples were selectively obtained treatment‐naïve patients with cancer under real‐time imaging. Tissue level calculations, immunohistochemistry, RNA sequencing performed. The mean tissue levels at sampling sites 32.2%, 70.8%,...
Hypoxic microenvironment is prominent in advanced esophageal squamous cell carcinoma (ESCC). However, it unclear whether ESCC becomes hypoxic when remains the mucosal layer or as invades submucosal layer. We aimed to investigate intramucosal (Tis-T1a) invasive (T1b) using endoscopic dissection samples.We evaluated expression of hypoxia markers including inducible factor 1α (HIF-1α), carbonic anhydrase IX (CAIX), and glucose transporter 1 (GLUT1) by H-score vessel density microvessel count...
Endoscopic resection (ER) with bipolar snare, in which the electric current only passes through tissue between device's two electrodes, is a prominent method used to prevent perforation due electricity potentially. ER using snare or without submucosal injection enabled safe of colorectal lesions measuring 10-15 mm an ex vivo porcine model. expected have good treatment outcomes lesions, high safety even injection. However, no clinical reports compared and injection.To compare polypectomy hot...
Abstract Objectives For early gastrointestinal lesions, size is an important factor in the selection of treatment. Virtual scale endoscope (VSE) a newly developed that can measure more accurately than visual measurement. This study aimed to investigate whether VSE measurement accurate for lesions various sizes and morphologies. Methods prospectively enrolled patients with ≤20 mm visually. Lesion were measured tract visually, on endoscopic resection specimens VSE, finally using ruler. The...
Summary In submucosal invasive adenocarcinoma of the esophagogastric junction (pT1b-SM AEG), extent tumor (SM) invasion is measured using vertical depth SM with muscularis mucosa. This study aimed to investigate whether thickness and without accounting for mucosa were superior as metastasis predictors. We enrolled patients pT1b-SM AEG who underwent endoscopic resection or surgical (SR) at our institution between January 2011 September 2019 followed up ≥2 years. The relationship...
Few reports have detailed improvements in the quality of colonoscopies with continuous training post-fellowship completion. We examined changes colonoscopy performance among trainees during our advanced endoscopy program.
Abstract Background Photodynamic therapy (PDT) using talaporfin sodium is known as the effective, safe, and less invasive treatment for local failure after chemoradiotherapy (CRT) or radiotherapy (RT) esophageal squamous cell carcinoma (ESCC). The secondary primary ESCC sometimes occur at different site CRT/RT other cancer, PDT may be considered such lesion if endoscopic resection surgery are not suitable patients. However, actual therapeutic efficacy remains unclear. This study aims to...
Objectives The resection of vertical margin‐negative submucosally invasive colorectal cancer (CRC) relies on the pathological risk assessment lymph node metastasis. However, no large‐scale study has clarified endoscopic (ER) outcome for CRC, focusing margin status. This retrospective aimed to examine involvement in ER CRC and explore treatment consequences associated with Methods We analyzed 395 cases 389 patients who underwent at our hospital between 2008 2020. presence residual tumors...
Abstract Purpose The pathological diagnosis of surgically resected gastric cancer involves both a macroscopic by gross observation and microscopic microscopy. Macroscopic determines the location stage disease involvement other organs surgical margin. Lesion recognition is thus an important diagnostic step that requires skilled pathologist. Nonetheless, artificial intelligence (AI) technologies could allow even inexperienced doctors laboratory technicians to examine specimens without need for...