A5020192649- Child Nutrition and Water Access
- Trace Elements in Health
- Iron Metabolism and Disorders
- Folate and B Vitamins Research
- Pregnancy and Medication Impact
- Antioxidant Activity and Oxidative Stress
- Infant Development and Preterm Care
- Food Security and Health in Diverse Populations
- Hemoglobinopathies and Related Disorders
- Retinoids in leukemia and cellular processes
- Heavy Metal Exposure and Toxicity
- Selenium in Biological Systems
- Vitamin C and Antioxidants Research
- Child Nutrition and Feeding Issues
University of Malawi
2020-2025
Kamuzu University of Health Sciences
2022-2023
Kamuzu Central Hospital
2022-2023
Abstract Zinc (Zn) is an essential nutrient for human health. In Ethiopia, a high prevalence of Zn deficiency has been reported. To explore demographic variation and spatial dependencies in the status Ethiopian population, we analyzed archived serum samples (n = 3373) from 2015 National Micronutrient Survey (ENMS), cross-sectional survey young children, school-age women reproductive age (WRA) men conducted all 9 regions two city administration Ethiopia. Serum concentrations, measured using...
Abstract Large‐scale food fortification may be a cost‐effective intervention to increase micronutrient supplies in the system when implemented under appropriate conditions, yet it is unclear if current strategies can equitably benefit populations with greatest needs. This study developed mathematical modeling framework for comparing scenarios across different contexts. It was applied model potential contributions of three vehicles (oil, sugar, and wheat flour) toward meeting dietary...
Background: Selenium deficiency is widespread in the Malawi population. The selenium concentration maize, staple food crop of Malawi, can be increased by applying selenium-enriched fertilizers. It unknown whether this strategy, called agronomic biofortification, effective at alleviating deficiency. Objectives: aim Addressing Hidden Hunger with Agronomy (AHHA) trial was to determine consumption maize flour, agronomically-biofortified selenium, affected serum concentrations women, and children...
Abstract Inflammation and infections such as malaria affect concentrations of many micronutrient biomarkers, hence estimates nutritional status. We aimed to assess the relationship between infection biomarker in pre-school children (PSC), school-age (SAC) women reproductive age (WRA) Malawi, examine potential role immunity on biomarkers. Data from 2015/2016 Malawi survey were used. The associations current or recent infection, detected by rapid diagnostic test, concentration serum ferritin,...
Serum zinc concentration (SZC) is used widely to assess population-level status. Its decreases during inflammatory responses, which can affect the interpretation of results. This study aimed re-estimate prevalence deficiency in Malawi based on 2015–2016 Micronutrient Survey (MNS) data, by adjusting SZC measures with markers inflammation. and inflammation data from 2760 participants were analysed. Adjustments made using: (1) The Internal Correction Factor (ICF) method geometric means, (2)...
Retinol Binding Protein (RBP) is responsible for the transport of serum retinol (SR) to target tissue in body. Since RBP relatively easy and cheap measure, it widely used national Micronutrient Surveys (MNS) as a proxy SR determine vitamin A status. By regressing concentration against measured subset survey population, one can define population-specific threshold that indicates deficiency (VAD). However, relationship between concentrations affected by various factors including inflammation....
Population-level assessment of zinc deficiency remains a challenge due to the lack suitable biomarkers. Spot urinary concentration (UZC) has potential provide information on population status in large-scale surveys, but there is no established cut-off point indicating deficiency. A strong correlation between this biomarker and an such as serum (SZC) paired samples (i.e., from same individual), could identify thresholds This study, therefore, aimed regress spot UZC school-aged children women...