A5101464747- Advanced Photocatalysis Techniques
- Polymer composites and self-healing
- Analytical chemistry methods development
- Nanoparticle-Based Drug Delivery
- Intensive Care Unit Cognitive Disorders
- Advanced Sensor and Energy Harvesting Materials
- Advanced Polymer Synthesis and Characterization
- Gas Sensing Nanomaterials and Sensors
- Conducting polymers and applications
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Forensic Toxicology and Drug Analysis
- Anesthesia and Sedative Agents
- Polymer Surface Interaction Studies
- Copper-based nanomaterials and applications
- Nanoplatforms for cancer theranostics
- Biosensors and Analytical Detection
- Cellular and Composite Structures
- Polymer Foaming and Composites
- Healthcare Decision-Making and Restraints
- biodegradable polymer synthesis and properties
- Nosocomial Infections in ICU
- Click Chemistry and Applications
- Synthesis and properties of polymers
- TiO2 Photocatalysis and Solar Cells
Sichuan University
2021-2024
Hunan University of Technology
2023-2024
Sichuan Research Center of New Materials
2022-2024
Beijing Institute of Technology
2024
West China Hospital of Sichuan University
2022-2024
Harbin Institute of Technology
2024
Integrated Chinese Medicine (China)
2024
Guangzhou University
2019-2023
Northwestern Polytechnical University
2020-2023
Ministry of Industry and Information Technology
2020-2023
Cyclic brush (cb) copolymers that are composed of a cyclic core densely grafted with radiating polymer brushes have emerged recently as innovative materials for both fundamental and practical investigations due to their capability form unimolecular micelles greater stability relative the analogues self-assembled by bottlebrush (bb) an identical molecular weight (MW). However, compared extensive intensive studies on cb homogeneous brushes, preparation application heterogeneous grafts remains...
Polyurethane elastomers with mechanical robustness, tear resistance, and healing efficiency hold great potential in wearable sensors soft robots. However, achieving excellent properties healable capability simultaneously remains highly desirable but exclusive. Herein, we propose a straightforward procedure for double modification of poly(urethane-urea) (PUU) via thiolactone chemistry, two different dynamic cross-linking bonds (disulfide linkages Zn2+/imidazole coordination) are successively...
Abstract Background Cardiovascular disease (CVD) is the leading cause of mortality, and vascular calcification has been highly correlated with CVD events. Abdominal aortic (AAC) shown to predict subclinical incident However, relationship between vitamin C abdominal remains unclear. Objective To investigate dietary AAC among adult population in US. Methods The National Health Nutrition Examination Survey (NHANES) 2013–2014 provided data for cross-sectional study. 2297 subjects (1089 males)...
Polymeric prodrugs with precisely controlled drug loading content (DLC) and rapid intracellular destabilization generally require complicated chemistry that hinders large-scale manufacture. For this purpose, we reported in study a facile construction of reduction-sensitive amphiphilic polyprodrugs an anticancer drug, 10-hydroxycamptothecin (HCPT), hydrophilic poly(ethylene oxide) (PEG) moiety as the alternating building blocks multiblock copolymer using Cu(I)-catalyzed azide–alkyne...
The preparation of various types miktoarm star polymers with precisely controlled structures (A2B, ABC, AB2C2, etc.) has made significant progress due to the considerable advances in synthetic strategies, including multistep protections/deprotections, orthogonality, and integration different polymerization techniques. However, compared well-developed synthesis methodologies, investigations on copolymers as drug delivery vehicles remain relatively unexplored, especially for relationship their...
Conjugation of various active targeting ligands to the surface nanocarriers realize specific recognition by corresponding receptors localized on membrane cancer cells has provided a powerful means toward enhanced therapy. Folic acid (FA) is one most used due overexpressed FA in many cell lines. However, conjugation hydrophobic usually alters hydrophilic/hydrophobic balance stabilized nanoparticles, leading their thermodynamic instability and subsequent formation aggregates, which apparently...
Elastomers that are self-healable, recyclable, reprocessable, and customizable in mechanical properties desired for numerous industries but remain challenging to achieve. Herein, we develop novel poly(urethane–urea) (PUU) elastomers involving triple dynamic bonds a convenient efficient manner. Briefly, prepolymer based on polyetheramine terminated by asymmetric alicyclic diisocyanate was synthesized chain-extended with two diamines generate PUU elastomer containing hydrogen (H bonds)...
Abstract Crystalline FeVO 4 nanopolyhedron (FVO NPH) photoelectrodes are successfully prepared by using an in situ solid‐state transformation from hydrothermal FeOOH films via adding vanadium precursor and following thermal treatments. The FVO NPH possess uniformly dispersed polyhedral nanocrystals that directly grow on the conductive substrate with tunable film thicknesses. unique morphology enables outstanding photo‐electrocatalytic performance, optimized photoelectrode, which was annealed...
Fluid therapy is an important component of intensive care management, however, optimal fluid management unknown. The relationship between balance and ventilator-associated events has not been well established. This study investigated the dose-response events.Nested case-control study.The was based on a well-established, research-oriented registry healthcare-associated infections at ICUs West China Hospital system (Chengdu, China).A total 1,528 event cases with 3,038 matched controls, who...
We report in this communication the first preparation of triblock copolymer-based biocleavable shell cross-linked (SCL) hybrid micelles using a reducible silica monomer that integrates polymerizable methacrylate structure and situ cross-linkers precursors via disulfide bond. The developed herein offers highly straightforward robust strategy toward bioreducible silica-based nanoparticles for controlled drug release.
Coating WO<sub>3</sub> nanoplates with BiFeO<sub>3</sub> ferroelectric nanolayer can significantly enhances the photoanode’s charge density, and improves its transport separation property charges’ lifetime, leading to an enhanced PEC activity.
Although protein imprinted materials with multiple templates are developed to selectively separate different proteins, it is difficult achieve the programmed adsorption and separation of proteins using one material, because available constructed through irreversible crosslinking their structures unprogrammable non-reconstructive. Herein, a novel nanosphere (MS@PTL-g-PNIPAM) designed, which not only temperature pH responsive but also can dynamically reversibly crosslink/de-crosslink under...
The association between blood transfusion and ventilator-associated events (VAEs) has not been fully understood. We sought to determine whether increases the risk of a VAE.Nested case-control study.This study was based on registry healthcare-associated infections in intensive care units at West China Hospital system.1,657 VAE cases 3,293 matched controls were identified.For each case, 2 randomly selected using incidence density sampling. defined as time-dependent variable, we used weighted...
Background: As the first-line treatment for mechanically ventilated patients with critical illness, fentanyl and its analogs (e.g., sufentanil remifentanil) are commonly used in intensive care unit (ICU). However, pharmacokinetics, metabolism, potency of these agents differed. Their effects on clinical outcomes have not been well-understood. Materials Methods: Using a well-established registry, we conducted cohort study. Patients who consistently underwent mechanical ventilation (MV) more...