- Synthesis and biological activity
- Phytochemical Studies and Bioactivities
- Nanotechnology research and applications
- Free Radicals and Antioxidants
- Multicomponent Synthesis of Heterocycles
- Bacillus and Francisella bacterial research
- Poxvirus research and outbreaks
- Phytochemistry and Bioactive Compounds
- Virology and Viral Diseases
- Graphene and Nanomaterials Applications
- Computational Drug Discovery Methods
- Medicinal plant effects and applications
- Bioactive Compounds and Antitumor Agents
Centurion University of Technology and Management
2023-2025
Siksha O Anusandhan University
2019
The world faces multiple public health emergencies simultaneously, such as COVID-19 and Monkeypox (mpox). mpox, from being a neglected disease, has emerged global threat that spread to more than 100 nonendemic countries, even been spreading for 3 years now. general mpox symptoms are similar chickenpox measles, thus leading possible misdiagnosis. This study aimed at facilitating rapid high-brevity diagnosis. Reportedly, circulates among particular groups, sexually promiscuous gay bisexuals....
Present study aimed to evaluate the phytoconstituents of aqueous extracts stem and fruits Olax psittacorum as well free radical scavenging antibacterial activity extracts. Free activities were evaluated through DPPH assay, ABTS phosphomolybdate hydrogen peroxide assay reducing power using ascorbic acid standard. Well diffusion method was adopted for evaluation extract against Staphylococcus aureus, Bacillus stereothermophillus, Pseudomonas aeruginosa, Vibrio cholera, Escherichia coli...
Glimepiride (GLM) is one of the potential antidiabetic drugs used in clinics for a long time. It currently combination with metformin along other drugs, but has shown various complications patients from long-term use. Thus, hypothesis to use lower dose GLM non-toxic class flavonoid, naringin (NARN), better therapy minimal side-effects. Initially, we assessed binding efficacy and NARN against nine putative target enzymes using AutoDock 4.2 software. We also analysed drug chemistry,...
Objective: This work aims to evaluate the combined anti-diabetic effects of metformin and catechin in vitro silico. Methods: In vitro, potentials (α-amylase α-glucosidase) catechin, metformin, a combination were studied at different concentrations using acarbose as standard. An silico study determined their binding interactions with α-amylase (PDB ID: 1hvx) α-glucosidase 5zcb). The molecular docking further revealed energy interacting residues docked 3D structure standard receptors. Results:...