A5033113558- Voice and Speech Disorders
- Parkinson's Disease Mechanisms and Treatments
- Light effects on plants
- Lung Cancer Research Studies
- Plant Molecular Biology Research
- Cancer therapeutics and mechanisms
- Speech and dialogue systems
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Insect Resistance and Genetics
- Insect Utilization and Effects
- PARP inhibition in cancer therapy
- Neurological disorders and treatments
- Genetic Neurodegenerative Diseases
- Topic Modeling
- Multimodal Machine Learning Applications
- Photosynthetic Processes and Mechanisms
- Greenhouse Technology and Climate Control
- Neurobiology and Insect Physiology Research
- Cancer Mechanisms and Therapy
High Magnetic Field Laboratory
2024
Chinese Academy of Sciences
2024
Hebei Agricultural University
2022-2024
Chinese University of Hong Kong, Shenzhen
2024
Hefei Institutes of Physical Science
2024
Jilin University
2021
Qinghai Provincial Peoples Hospital
2021
Centre de Recherche Inria Bordeaux - Sud-Ouest
2018
Institut national de recherche en informatique et en automatique
2018
Abstract PLK1 is currently at the forefront of mitotic research and has emerged as a potential target for small cell lung cancer (SCLC) therapy. However, factors influencing efficacy inhibitors remain unclear. Herein, BRCA1 was identified key factor affecting response SCLC cells to BI-2536. Targeting AURKA with alisertib, non-toxic concentration, reduced BI-2536-induced accumulation RAD51, leading DNA repair defects death in cells. In vivo experiments confirmed that combining BI-2536...
Light is an important environmental factor influencing plant growth and development. However, artificial light supplement difficult to spread for its high energy consumption. In recent years, rare-earth conversion film (RPO) covering being focused on be a new technology study the mechanism of affecting Compared with polyolefin (PO), RPO advanced temperature environment inside greenhouse. Ultimately, improved higher yield were detected because photosynthesis, Rubisco activity small subunit...
Purpose: Depression seems to aggravate progression of Parkinson's disease (PD). Hypoxia stress may be one the pathogenic factors leading PD. We investigated characteristics PD and related depression (PDD) at high altitude (mean ≥ 2300 m). Patients Methods: Totally 221 patients three different nationalities (Han, Hui, Tibetan) were recruited in a high-altitude hospital. was present 55.6% them. Patient data examined, including demographic information, medical history, duration family history....
Parkinsonism refers to Parkinsons disease (PD) and Atypical parkinsonian syndromes (APS). Speech disorder is a common early symptom in which makes speech analysis very important research area for the purpose of diagnosis. Most have however focused on discrimination between PD healthy controls. Such does not take into account fact that APS are similar stages. The main problem has be addressed first then differential diagnosis: within APS. This paper continuation an earlier pioneer work...
Insects rely on their olfactory systems in antennae to recognize sex pheromones and plant volatiles surrounding environments. Some carboxylesterases (CXEs) are odorant-degrading enzymes (ODEs), degrading odorant signals protect the neurons against continuous excitation. However, there is no report about CXEs Holotrichia parallela , one of most major agricultural underground pests China. In present study, 20 candidate were identified based transcriptome analysis female male antennae. Sequence...
We present a knowledge-grounded dialog system developed for the ninth Dialog System Technology Challenge (DSTC9) Track 1 - Beyond Domain APIs: Task-oriented Conversational Modeling with Unstructured Knowledge Access. leverage transfer learning existing language models to accomplish tasks in this challenge track. Specifically, we divided task into four sub-tasks and fine-tuned several Transformer on each of sub-tasks. made additional changes that yielded gains both performance efficiency,...
<title>Abstract</title> Abnormal accumulation of Poly(ADP-ribose) polymerase 1 (PARP1) is implicated in the progression several cancers. However, mechanisms responsible for PARP1 protein stabilization remain incompletely understood. In this study, we identify E3 ubiquitin ligase tripartite motif-containing 21 (TRIM21) as a novel PARP1-binding partner. directly interacts with TRIM21 via its HD domain, while PRY-SPRY domain essential interaction. Consequently, facilitates polyubiquitination at...
Light conversion films are crucial for optimizing vegetable crop production in greenhouses, particularly during winter and spring seasons. This study investigated the effects of a europium-based light film (RPO) compared to traditional polyolefin (PO film, control) on cucumber (Cucumis sativus L.) cultivation, focusing handle length, yield, fruit quality randomized complete block design with three replications. Results demonstrated that RPO significantly enhanced multiple parameters: overall...