- Silk-based biomaterials and applications
- Electrospun Nanofibers in Biomedical Applications
- Nanoplatforms for cancer theranostics
- Advanced Sensor and Energy Harvesting Materials
- Photodynamic Therapy Research Studies
- Advanced Nanomaterials in Catalysis
- Conducting polymers and applications
- Phytochemistry and Biological Activities
- Cancer, Stress, Anesthesia, and Immune Response
- Polymer Nanocomposite Synthesis and Irradiation
- Surface Modification and Superhydrophobicity
- 3D Printing in Biomedical Research
- Bone Tissue Engineering Materials
- Industrial Technology and Control Systems
- Optical Imaging and Spectroscopy Techniques
- Tactile and Sensory Interactions
- Advanced Machining and Optimization Techniques
- Sphingolipid Metabolism and Signaling
- Interactive and Immersive Displays
- Phytochemistry and Bioactive Compounds
- Polymer composites and self-healing
- Photoacoustic and Ultrasonic Imaging
- Bacteriophages and microbial interactions
- Advanced Photocatalysis Techniques
- Biochemical and biochemical processes
Stanford University
2019-2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2022
ShanghaiTech University
2020-2021
Beihang University
2011-2020
Central South University
2019-2020
Xiamen University
2019
Southwest Minzu University
2019
Wuhan Institute of Technology
2018
Harvard University
2018
National Research Center for Rehabilitation Technical Aids
2018
Development of second near-infrared (NIR-II) nanoparticles (NPs) with high biocompatibility, low toxicity, and singlet oxygen quantum yield (ΦΔ) to prevent tumor recurrence is highly desirable in molecular imaging photodynamic/immune combination therapy. Here, theranostic photosensitizer BODIPY (BDP)-I-N-anti-PD-L1 NPs were developed by encapsulating the BDP-I-N amphipathic poly(styrene-co-chloromethylstyrene)-graft-poly(ethylene glycol) nanocarriers through self-assembly functionalization...
Recently, various second near-infrared window (NIR-II, 1000-1700 nm) fluorophores have been synthesized for in vivo imaging with nonradiation, high resolution, and low autofluorescence. However, most of the NIR-II fluorophores, especially inorganic nanoprobes, are mainly retained reticuloendothelial system (RES) such as liver spleen, leading to long-term safety concerns. Herein, a type lanthanide-based excretable nanoparticle, RENPs@Lips, which can be quickly cleared out body after...
Abstract The dysfunction of the circulatory system leads to various pathological processes with high morbidity. Recently, fluorescence imaging in near‐infrared II (NIR‐II) window (1000–1700 nm) has attracted immense attention many biological processes. rapid metabolism and low toxicity some NIR‐II organic small molecules indicate their feasibility for use visualizing system. However, most reported presently encounter such dilemmas as complicated synthetic procedures quantum yields (QY). To...
Ionotronic skin (i-skin) has drawn considerable attention, because it can interface with different systems to sense and respond external stimuli, such as force temperature. However, safety issues, biosecurity, sustainability, in use, are rarely considered i-skin designs. In this study, a flame-retardant biosafe was developed by using silk fibroin Ca2+ ions starting materials. The structures, performance, issues of the i-skins were well-balanced. resultant not only maintained advantages...
Despite advancements in wound healing techniques and devices, new treatments are needed to improve therapeutic outcomes. This study aimed evaluate the potential use of a biomaterial engineered from human urine-derived stem cells (USCs) polycaprolactone/gelatin (PCL/GT) for healing.USCs were isolated healthy individuals. To fabricate PCL/GT composite meshes, twin-nozzle electrospinning used spin PCL gelatin solutions normal organic solvents. The morphologies hydrophilicity properties...
Abstract The emergence of ionotronic materials has substantially extended the applications artificial skins by allowing intimate interfaces between electronics and biological/bionic surfaces toward achieving improved sensing communication with surrounding stimuli. However, are intrinsically temperature dependent, since water molecules play crucial roles in regulating both mechanical ionic conductivity materials. Hence, most will fail at temperatures below 0 °C. In this study, a highly...
Silk fibroin hydrogel ionotronics (SFHIs) have received increasing attention due to their good mechanical and electrical adjustability, as well environmental responsiveness friendliness. However, fundamental issues related the conductivity mechanisms influences on temperature humidity responses are still unclear. In this study, conductive of SFHIs were investigated by combining experimental characterization with theoretical analysis. The results suggested vital role hydrated protons in...
A significant limitation in the engineering of artificial small-diameter vascular scaffolds is that number endothelial cells (ECs) not sufficient to generate a confluent coverage scaffolds, so surfaces form thrombus via platelet adhesion and aggregation. Thrombus decrease relies on three-dimensional (3D) mimic natural extracellular matrix (ECM) as templates regulate cell behavior facilitate tissue maturation. Here, we developed 3D consisting silk fibroin (SF) nanofibers homogeneous...
In this study, we find that silk fibroin as an antioxidant is capable of scavenging OH˙ and accelerating the degradation water-soluble fullerene, which provides further insight into application WSF in intratracheal instillation inhalation.
Interactive displays have been intensively used in consumer electronics, e.g., smartphones, for providing highly efficient human-machine interactions, assisting users to process a vast amount of data. However, current mainstream interactive only support 2-dimensional detection, strongly limiting user experience. In this paper, we present piezoelectric and capacitive based technique obtaining 4-dimensional including (x-y axis) location, force, hovers sensing displays. Here, electrodes are...
Low stability of globular protein droplets in emulsion significantly limits their applications drug encapsulation, long-term storage, and controlled release. Here, a microfluidic flow-focusing device was utilized to synthesize horseradish peroxidase (HRP)-loaded silk fibroin microdroplets. The two immiscible streams were regenerated by solution mixture 95 wt. % sunflower oil 5 span 80 as the dispersed continuous phases, respectively. In this study, water-in-oil microdroplets homogeneously...
Aiming at the data acquisition and monitoring of energy consumption in intelligent CNC machine tools machining processes, a design application scheme multifunctional integrated system based on current, voltage, power sensors MTConnect protocol is proposed. The software hardware module transmission designed. "plug play" signal devices used for real-time process are developed implemented, multiple device networking given. test result shows that multi-functional can effectively obtain such as...
Organic fluorophores/photosensitizers have been widely used in biological imaging and photodynamic photothermal combination therapy the first near-infrared windows. However, their applications second (NIR-II) windows are still limited primarily owing to low fluorescence quantum yields (QYs). Here, a boron dipyrromethene (BDP) as molecularly engineered thiophene donor unit with high QYs redshift is created. Thiophene insertion initiates substantial redshifts of absorbance, compared its...