A5079963514- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sepsis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Sarcoidosis and Beryllium Toxicity Research
- Foot and Ankle Surgery
- Tendon Structure and Treatment
- Diabetic Foot Ulcer Assessment and Management
- Obstructive Sleep Apnea Research
- Lower Extremity Biomechanics and Pathologies
- Sports injuries and prevention
- Bone fractures and treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 and Mental Health
- Orthopedic Surgery and Rehabilitation
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Aortic aneurysm repair treatments
- Hip and Femur Fractures
- Orthopedic Infections and Treatments
- Antifungal resistance and susceptibility
- Shoulder Injury and Treatment
- Neuroscience of respiration and sleep
- Thyroid and Parathyroid Surgery
- Seed and Plant Biochemistry
King's College London
2021-2025
Barts Health NHS Trust
2023-2024
Cadila Healthcare (India)
2021-2023
Royal London Hospital
2023
National Institute of Arthritis and Musculoskeletal and Skin Diseases
2023
National Institutes of Health
2023
King's College Hospital NHS Foundation Trust
2018-2022
King's College Hospital
2012-2022
Broomfield Hospital
2022
Gujarat Technological University
2022
Total knee arthroplasty (TKA) and total hip (THA) are recognised proven interventions for patients with advanced arthritis. Studies to date have demonstrated a steady increase in the requirement primary revision procedures. Projected estimates made United States show that by 2030 demand TKA will grow 673% 601% from level 2005. For THA projected 174% 137% surgery, respectively. The purpose of this study was see if those predictions were similar England Wales using data National Joint Registry...
Coronavirus disease (COVID-19) causes an immunosuppressed state and increases risk of secondary infections like mucormycosis. We evaluated clinical features, predisposing factors, diagnosis outcomes for mucormycosis among patients with COVID-19 infection. This prospective, observational, multi-centre study included 47 consecutive mucormycosis, diagnosed during their course illness, between January 3 March 27, 2021. Data regarding demography, underlying medical conditions, illness treatment...
A standardised approach to assessing COVID-19 survivors has not been established, largely due the paucity of data on medium- and long-term sequelae. Interval chest radiography is recommended following community-acquired pneumonia; however, its utility in monitoring recovery from pneumonia remains unclear.This was a prospective single-centre observational cohort study. Patients hospitalised with severe (admission duration ≥48 h oxygen requirement ≥40% or critical care admission) underwent...
<i>Background/Aims:</i> The aim was to examine the influence of statin therapy on natural history atherosclerotic renal artery stenosis (RAS). <i>Methods:</i> Our hospital renovascular disease (ARVD) database analysed for patients who underwent repeat angiography during clinical follow-up. Patients with ≧1 RAS lesion and ≧4 months between baseline were analysed. 79 included. Baseline arterial anatomy classified as normal, ≤50% RAS, >50% or occlusion....
Abstract Background & Aims Acute‐on‐chronic liver failure ( ACLF ) has a rapidly progressive disease course associated with significant mortality. The prevalence of clinically cerebral oedema in is unknown. Methods We aimed to describe the cohort adult (>18 years). identified patients admitted single, specialist intensive care unit between January 2005 and 2011 high‐grade hepatic encephalopathy (≥3) clinical picture either or chronic CLD ). Patients who had undergone cranial CT...
Background The Covid-19 pandemic in the United Kingdom has seen two waves; first starting March 2020 and second late October 2020. It is not known whether outcomes for those admitted with severe Covid were different waves. Methods study population comprised all patients to a 1,500-bed London Hospital Trust between 2021, who tested positive by PCR within 3-days of admissions. Primary outcome was death 28-days admission. Socio-demographics (age, sex, ethnicity), hypertension, diabetes,...
Abstract Background Primary prevention implantable cardioverter-defibrillators (ICDs) are recommended for patients with heart failure reduced ejection fraction. Previous studies have shown that a higher number of prescribed guideline-directed medical therapy (GDMT) medications improves survival rates at 2 years post-ICD implantation, though long-term data is lacking. Purpose This study investigated the impact GDMT, and uniquely, antiarrhythmic medications, on all-cause mortality following...
To report the 1-year clinical outcomes from GORE EXCLUDER Conformable AAA Endoprosthesis system in US regulatory trial.The study is a prospective, multicenter, investigational device exemption trial at 31 sites with core laboratory assessment of imaging and independent event adjudication. The primary safety (incidence major adverse events 30 days) effectiveness end points (successful aneurysm treatment 1 year) were assessed cohort patients abdominal aortic aneurysms (AAAs).We enrolled 80...
Background This study investigated the utility of ultrasound (US), 99mTc-Sestamibi scintigraphy (Sestamibi), and four-dimensional computed tomography (4DCT) for pre-operative localization a single abnormal parathyroid gland prior to minimally invasive parathyroidectomy (MIP) determine optimum scans facilitate MIP. Methods Patients with primary hyperparathyroidism who underwent curative at Broomfield Hospital, Mid South Essex NHS Foundation Trust between 2009 2018 were included. Diagnostic...
Tarsometatarsal (TMT) arthritis is characterized by instability and pain in the foot. The commonest cause post-traumatic arthritis. A Lisfranc injury involves articulation between medial cuneiform base of second metatarsal, which considered a keystone to midfoot integrity. Neglected or undertreated joint complex leads secondary significant disability. We present case young male patient with two-year-old neglected osteoarthritis first, second, fourth TMT joints, we treated surgically...
Distal ulna groove morphology is likely to have a significant role in extensor carpi ulnaris (ECU) tendon stability. The development of robust anatomical classification system, would be beneficial further research into ulnar sided wrist pain and use rationalising treatment regimes.Cadaveric specimens as well MRI scans patients with non-specific were analysed independently by 3 orthopaedic surgeons twice test the integrity system. following system was developed for distal groove; Flat =...
In 2011, the U.S. Department of Health and Human Services sent a letter to state Medicaid directors explaining need for oversight psychiatric prescriptions children with mental health disorders. The National Committee Quality Alliance proposed 3 quality measures rating managed care organizations (MCOs) that involve use second-generation or atypical antipsychotics in children. order ensure appropriate effectively manage children, MCOs better understand factors influence medication treatment...