A5002905344- Neurological disorders and treatments
- Botulinum Toxin and Related Neurological Disorders
- Pain Management and Treatment
- Parkinson's Disease Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Musculoskeletal pain and rehabilitation
- Genetic Neurodegenerative Diseases
- Trigeminal Neuralgia and Treatments
- Spine and Intervertebral Disc Pathology
- Glycogen Storage Diseases and Myoclonus
- Pain Mechanisms and Treatments
- Pain Management and Placebo Effect
- Pain Management and Opioid Use
- Obsessive-Compulsive Spectrum Disorders
- History of Medical Practice
- Medical research and treatments
- Neuroscience, Education and Cognitive Function
- Glioma Diagnosis and Treatment
- Parkinson's Disease and Spinal Disorders
- Developmental and Educational Neuropsychology
- Long-Term Effects of COVID-19
- Anesthesia and Pain Management
- Cervical and Thoracic Myelopathy
- Ethics and bioethics in healthcare
- Neurological and metabolic disorders
University of Buenos Aires
2009-2024
Universidad de Morón
2012-2023
Instituto de Neurología Cognitiva
2013-2022
Asociación para la Conservación de la Cuenca Amazónica
2022
Basildon Hospital
2022
Fondazione Roma
2022
Favaloro Foundation
2022
Instituto de Olhos de Goiânia
2018
Foundation for Biomedical Research
2013
Hospital de Clínicas "José de San Martín"
2007-2008
Additional safe and efficacious vaccines are needed to control the COVID-19 pandemic. We aimed analyse efficacy safety of CVnCoV SARS-CoV-2 mRNA vaccine candidate.HERALD is a randomised, observer-blinded, placebo-controlled, phase 2b/3 clinical trial conducted in 47 centres ten countries Europe Latin America. By use an interactive web response system stratification by country age group (18-60 years ≥61 years), adults with no history virologically confirmed were randomly assigned (1:1)...
A double-blind, randomized, placebo-controlled study of patients with essential trigeminal neuralgia and treatment a single injection onabotulinum toxin (BTX) was carried out. The efficacy, safety, tolerability either 1 mL 0.9% saline plus 50 U BTX or only injected subcutaneously in the affected area were evaluated. Cases involvement third branch nerve also received intramuscularly 10 matching placebo masseter muscle, ipsilateral to pain location. Pain assessed visual analog scale (VAS)....
Botulinum toxin has been thoroughly studied as a potential tool in the treatment of several pain syndromes. Therefore, we assessed clinical effects botulinum type A injections 12 patients with otherwise unresponsive idiopathic trigeminal neuralgia. Patients were infiltrated 20-50 units trigger zones. Those who presented mandibular involvement also masseter muscle. The on weekly basis using Visual Analogic Scale for pain. Ten our reported significant benefit from injections, reduction or even...
Aim: The availability of long-term (>2 years) safety outcomes spinal cord stimulation (SCS) remains limited. We evaluated in a global SCS registry for chronic pain. Methods: Participants were prospectively enrolled globally at 79 implanting centers and followed out to 3 years after device implantation. Results: Of 1881 participants enrolled, 1289 received permanent implant (1776 completed trial). annualized rate explant was 3.5% (all causes), 1.1% due inadequate pain relief. Total incidence...
Abstract To determine whether the immediate response to electrode implantation (micro lesion effect, MLE) in internal segment of globus pallidus (GPi) predicts symptom improvement with deep brain stimulation (DBS) at 6 months patients Parkinson's disease (PD) or generalized dystonia. Electrode subthalamic nucleus (STN) prior electrical has been reported predict a beneficial effect DBS PD, but this is also case for GPi either PD dystonia not established. We studied 20 (11 and 9 dystonia) who...
✓ Camptocormia is a well-known feature in cases of Parkinson disease (PD), and usually unresponsive to dopaminergic therapy. A 62-year old man with long history PD severe progressive camptocormia underwent bilateral pallidal stimulation. During the next 6 months sustained improvement trunk flexion was observed. After 14 follow up, patient's almost normal.
El objeto de análisis este trabajo consiste en la evaluación del mercado terapia estimulación cerebral profunda (DBS por sus siglas inglés), para el control los síntomas pacientes con enfermedad Parkinson Argentina, y su evolución tiempo.
Introduction. This project focuses on optimizing the initial programming process of electrodes implanted in subthalamic nucleus for deep brain stimulation patients with Parkinson's disease. Traditionally, this requires extensive testing ("contact testing") to determine which electrode contact(s) generate best response without adverse effects.Project Objective: To develop a predictive system based intraoperative multi-unit micro-recording data and postoperative images select most effective...
OBJECTIVE The aim of this study was to provide geographic comparisons deep brain stimulation (DBS) procedures in Latin America with the US and Europe regarding primary indications, demographic information, clinical device-related adverse events, technology used, patient outcomes using Medtronic Product Surveillance Registry data as July 31, 2021. METHODS Two thousand nine hundred twelve patients were enrolled registry (2782 received DBS 1580 are currently active). Fourteen countries...