A5088470119- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Cardiovascular and exercise physiology
- Cardiac Imaging and Diagnostics
- Pulmonary Hypertension Research and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Hemodynamic Monitoring and Therapy
- Cardiovascular Effects of Exercise
- Diabetes Treatment and Management
- Cardiovascular Disease and Adiposity
- Cardiac tumors and thrombi
- Nutrition and Health in Aging
- Cardiac Arrhythmias and Treatments
- Ultrasound in Clinical Applications
- Systemic Sclerosis and Related Diseases
- Atrial Fibrillation Management and Outcomes
- Gastroesophageal reflux and treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pericarditis and Cardiac Tamponade
- Infective Endocarditis Diagnosis and Management
- Dialysis and Renal Disease Management
- Fibroblast Growth Factor Research
- Coronary Artery Anomalies
Gunma University
2018-2025
Mayo Clinic in Arizona
2024
Mayo Clinic
2024
WinnMed
2024
Nihon University
2022
Gunma Prefectural Cardiovascular Center
2022
National Defense Medical College
2022
Gunma University Hospital
2022
National Hospital Organization
2014
Kure Medical Center
2014
Abstract Aims Left ventricular (LV) diastolic dysfunction and heart failure with preserved ejection fraction (HFpEF) are common cardiac complications of patients systemic sclerosis (SSc). Exercise stress echocardiography is often used in symptomatic SSc to detect abnormal increases pulmonary pressures during exercise, but the pathophysiologic prognostic significance exercise assess presence HFpEF these unclear. Methods results Patients (n=140) underwent ergometry simultaneous expired gas...
Exercise intolerance is a primary manifestation in patients with heart failure preserved ejection fraction (HFpEF) and associated abnormal hemodynamics poor quality of life. Two multiparametric scoring systems have been proposed to diagnose HFpEF. This study sought determine the performance H2FPEF HFA-PEFF scores for predicting exercise capacity echocardiographic findings intracardiac pressures during subjects dyspnea on exertion referred bicycle stress echocardiography. In subset,...
Background: Cardiac power output is a measure of cardiac performance, and its prognostic significance has been shown in heart failure (HF) with reduced ejection fraction. Patients HF preserved fraction may have altered but the relevance unknown. This study sought to determine association between clinical outcomes compare effect other measures performance including ventricular-arterial coupling mechanical efficiency. Methods: normalized left ventricular mass was assessed by echocardiography...
Abstract Background Delayed diagnosis of heart failure (HF) with preserved ejection fraction (HFpEF) can lead to poor clinical outcomes. Exercise stress testing, especially exercise echocardiography, plays a primary role in the early detection HFpEF among dyspnoeic patients, but its prognostic significance is unknown, as whether initiation guideline-directed therapy could improve outcomes such early-stage HFpEF. Methods and results Ergometry echocardiography was performed 368 patients...
BACKGROUND: Systemic arterial compliance and venous capacitance are typically impaired in patients with heart failure preserved ejection fraction (HFpEF), contributing to hemodynamic congestion stress. Sodium-glucose cotransporter-2 inhibitors reduce improve clinical outcomes HFpEF, but the mechanisms remain unclear. This study tested hypothesis that Dapagliflozin would systemic during exercise HFpEF. METHODS: In this secondary analysis from CAMEO-DAPA trial (Cardiac Metabolic Effects of...
Abstract Aims Exercise stress echocardiography (ESE) is often used to identify heart failure with preserved ejection fraction (HFpEF) in patients presenting dyspnea. However, diagnostic criteria have not been standardized. Here, we sought develop ESE-based diagnose HFpEF dyspneic patients. Methods and Results A total of 81 consecutive dyspnea who underwent exercise right catheterization ESE were evaluated. Diagnosis was ascertained by directly-measured hemodynamics (61 20 controls). Logistic...
Abstract Aims Lung ultrasound (LUS) may unmask occult heart failure with preserved ejection fraction (HFpEF) by demonstrating an increase in extravascular lung water (EVLW) during exercise. Here, we sought to examine the dynamic changes B-lines exercise identify optimal timeframe for HFpEF diagnosis. Methods and results Patients (n = 134) those without HF (controls, n 121) underwent a combination of stress echocardiography LUS simultaneous expired gas analysis EVLW. Exercise EVLW was defined...
Left atrial (LA) dysfunction is common in heart failure (HF) with preserved ejection fraction. However, data on the pathophysiologic impacts of impaired LA functional reserve remained limited. We sought to determine association abnormal dynamics during exercise cardiovascular reserve, capacity, and clinical outcomes.
Background Exercise-induced high heart rate may impair exercise tolerance by reducing diastolic filling time and ventricular in failure with preserved ejection fraction (HFpEF). Given the importance of chronotropic response, we hypothesized that reduction because exercise-induced increased would not cardiac output reserve capacity. We sought to determine association between rate, time, hemodynamics, capacity HFpEF. Methods Results Patients HFpEF (n=66) controls without HF (n=107) underwent...