A5081557600- Photoreceptor and optogenetics research
- Photosynthetic Processes and Mechanisms
- Advanced Drug Delivery Systems
- Nail Diseases and Treatments
- Enzyme Production and Characterization
- Studies on Chitinases and Chitosanases
- Bee Products Chemical Analysis
- Spectroscopy and Quantum Chemical Studies
- bioluminescence and chemiluminescence research
- Blood Coagulation and Thrombosis Mechanisms
- Synthesis and biological activity
- Antibiotics Pharmacokinetics and Efficacy
- Protein Hydrolysis and Bioactive Peptides
- Fungal Biology and Applications
- Bacterial biofilms and quorum sensing
- Fungal Infections and Studies
- Ocular Surface and Contact Lens
- Probiotics and Fermented Foods
- Vibrio bacteria research studies
- Drug Solubulity and Delivery Systems
- Antifungal resistance and susceptibility
- Lipid Membrane Structure and Behavior
- Mitochondrial Function and Pathology
- ATP Synthase and ATPases Research
- Essential Oils and Antimicrobial Activity
Manipal Academy of Higher Education
2020-2023
University of Arkansas at Fayetteville
2007-2010
Tinea are superficial fungal infections caused by dermatophytes. Luliconazole exhibits highest antifungal activity against Trichophyton spp. which major causative agents of dermatophytosis. However, luliconazole suffers from drawbacks such as less skin retention, low aqueous solubility and poor penetration. To overcome the limitations luliconazole, nanostructured lipid carriers (NLCs) were formulated. NLCs better permeation enhancers they increase occlusion hydration. The selection various...
Fungal keratitis is one of the leading causes ophthalmic mycosis affecting vision due to corneal scarring. Voriconazole (VRC) most preferred azole antifungal agent for treating ocular mycotic infections. Ocular drug delivery challenging shorter residence time formulation requiring frequent administration, poor patient compliance. The present study aimed at improving solubility, transcorneal permeation, and efficacy voriconazole via formation cyclodextrin-based ternary complexes incorporation...
Abstract Background Dandruff caused by Malassezia furfur is a prevailing fungal infection. Although ketoconazole (KTZ) widely intended for anti‐dandruff treatment, poor solubility, and epidermal permeability limits its use the marketed KTZ shampoo adversely effects scalp hair. Objective To prepare novel loaded with KTZ‐coated zinc oxide nanoparticles using green tea extract evaluate antifungal activity. Methods The was prepared synthesis characterized UV, FTIR, XRD, drug entrapment...
A carefully designed ammonium sulfate precipitation will simplify extraction of proteins and is considered to be a gold standard among various methods. Therefore, optimization can an important functional step in protein purification. The presence high amounts sulphate precludes direct detection many enzymatically active including reducing sugar assays (e.g. Nelson-Somogyi, Reissig 3,5-dinitrosalicylic acid methods) for assessing carbohydrases laminarinase (β (1-3)-glucanohydrolase),...
Novel antifungals are challenging to find as potential target may have close human orthologs. Among the pathogenic fungi, Candida albicans is most prevalent pathogen. Screening of actinomycetes for has been an aggressive area research since decades. For discovering newer metabolites against albicans, work was oriented in isolation evaluating antifungal activity their cultural extracts. A total 115 strains were isolated from different soil samples using Starch Casein Agar. Mueller Hinton Agar...
Novel Schiff’s bases bearing substituted 2-amino benzothiazole were synthesized by single step process through simple condensation of and benzaldehydes further characterized FTIR, 1HNMR, Mass spectrometry data. Antimicrobial activity compounds was performed agar diffusion method against a panel bacterial strains such as S. aureus, B. subtilis (Gram-positive bacteria), E. coli, P. aeruginosa (Gram-negative bacteria) fungal C. albicans A. niger. Compound S13 S17 had shown potent antifungal...
Colloidal chitin (CC) is a common substrate used in research work involving chitin-active enzymes (chitinases). Cell free supernatant (CFS) prepared from fermented broth. Preparation of CC and CFS usually involve large amounts liquid, which must be separated the solids. This necessitates use volume centrifugation facility, may not accessible to everyone. Filtration viable alternative centrifugation, several filter elements are described literature. Each those has its own set disadvantages...