- Diabetes Treatment and Management
- Cardiovascular Function and Risk Factors
- Orthopedic Infections and Treatments
- Pneumonia and Respiratory Infections
- Antibiotic Use and Resistance
- Infectious Encephalopathies and Encephalitis
- Gastroesophageal reflux and treatments
- Chronic Lymphocytic Leukemia Research
- Platelet Disorders and Treatments
- Metabolism, Diabetes, and Cancer
- Infectious Diseases and Tuberculosis
- Pharmaceutical Practices and Patient Outcomes
- Antibiotics Pharmacokinetics and Efficacy
- Complement system in diseases
- Respiratory and Cough-Related Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Parkinson's Disease Mechanisms and Treatments
- Potassium and Related Disorders
- Pharmaceutical studies and practices
- Antimicrobial Resistance in Staphylococcus
Glenmark Pharmaceuticals (India)
2024
B.J. Medical College
2022
Abstract Aims: The study aimed at evaluating efficacy and safety of Remogliflozin etabonate Vildagliptin fixed dose combination (FDC) compared to currently approved FDC Empagliflozin Linagliptin. Methods: A randomized, double-dummy, double-blind, active-controlled, parallel-group, two-arm, multi-center was conducted 26 sites across India. Type-2 diabetes mellitus (T2DM) patients aged between 18-65 years on metformin ≥1500 mg were randomized receive either Etabonate (RV) or Linagliptin (EL)...
Background: In patient of T2DM and HF, reduced ejection fraction (HFrEF) constitutes the majority HF cases, posing significant risk mortality. NYHA classification, recommended in global guidelines, independently predicts SGLT2i have shown to reduce incidence hospitalization for HF. Hence, this study was planned evaluate effectiveness Remogliflozin improving class patients with Methods: prospective, multicentre study, 250 HFrEF having Class I III, were enrolled. 125 allocated each (R)...
Background: Medication can cause an injury in the esophagus by local and systemic effect, leading to esophagitis. Many such medications have been identified as a of pill-induced This study was performed evaluate clinical endoscopic findings esophagitis.Methods: retrospective observational study, conducted among patients diagnosed endoscopically with esophagitis at Ansh gastroenterology clinic, Ahmedabad, India, from April 2017 March 2021. The data these were recorded pre-designed case record...
Thrombotic thrombocytopenic purpura (TTP) is a rare but fatal thrombotic microangiopathy. Circulating AntiADAMTS13 antibodies produced in response to various triggering events, such as vaccinations, autoimmune disorders, malignancy, and administration of several drugs lead acquired TTP (aTTP). This case concerns 26-year-old male with aTTP after receiving the second dose Covishield vaccine (Oxford-AstraZeneca COVID-19 vaccine, code-named AZD1222). He presented bruises, petechia, fatigue,...
Metronidazole, a commonly used antiprotozoal and antibacterial medication is usually safe rarely reported to cause serious side effects. Major nervous effects are peripheral ones, while central toxicity rare. Following the discontinuation of medication, clinical improvement seen in most cases. A 62 years old female patient was presented hospital after experiencing symptoms an unsteady gait, difficulty walking, impaired coordination arms legs, slurring speech, headache, tingling numbness both...
Objectives: The aim of the study was to evaluate a drug utilization pattern and use potentially inappropriate medications (PIMs) among geriatric patients admitted medical intensive care unit (MICU) tertiary teaching hospital. Methods: A prospective observational conducted MICU data relevant variables were collected in pre-designed case record form. Evaluation carried out using WHO core prescribing indicators, PIMs evaluated Beers criteria 2019. Results: average duration stay per patient...
Levofloxacin, a broad-spectrum, third-generation fluoroquinolone antibiotic, is rarely reported to cause life-threatening adverse effects, such as severe hypoglycaemia resulting in coma. This case concerns an elderly, non-diabetic patient induced by levofloxacin. A 61-year-old male was admitted with hypoglycaemia. Past medical history revealed treatment levofloxacin for pneumonia. During the hospital stay, treated multiple doses of 25 g dextrose 50% (D50), 2 1 mg glucagon, and continuous...