A5043194455- Diabetes and associated disorders
- Diabetes Management and Research
- Vitamin D Research Studies
- Pancreatic function and diabetes
- Thyroid Disorders and Treatments
- Sexual Differentiation and Disorders
- Adrenal Hormones and Disorders
- Vitamin C and Antioxidants Research
- Neonatal Health and Biochemistry
- Birth, Development, and Health
- Pituitary Gland Disorders and Treatments
- Urological Disorders and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Obesity, Physical Activity, Diet
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes Management and Education
- Adrenal and Paraganglionic Tumors
- Growth Hormone and Insulin-like Growth Factors
- Metabolism and Genetic Disorders
- Diabetes Treatment and Management
- Child Nutrition and Water Access
- Hormonal Regulation and Hypertension
- Climate Change and Health Impacts
- Neurological and metabolic disorders
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2016-2025
The Royal Melbourne Hospital
2000-2020
University of Birmingham
2016
Society of General Internal Medicine
2010
Government Medical College and Hospital
2000-2007
University of Lucknow
1997
University of Massachusetts Chan Medical School
1991
Background: Vitamin D and calcium deficiencies are common worldwide, causing nutritional rickets osteomalacia, which have a major impact on health, growth, development of infants, children, adolescents; the consequences can be lethal or last into adulthood. The goals this evidence-based consensus document to provide health care professionals with guidance for prevention, diagnosis, management policy makers framework work toward its eradication. Evidence: A systematic literature search...
Disorders of sex development (DSD) are congenital conditions in which chromosomal, gonadal, or phenotypic is atypical. Clinical management DSD often difficult and currently only 13% patients receive an accurate clinical genetic diagnosis. To address this we have developed a massively parallel sequencing targeted gene panel allows us to sequence all 64 known diagnostic genes candidate simultaneously. We analyzed DNA from the largest reported international cohort with (278 46,XY 48 46,XX DSD)....
Over the past 10 years, prevalence of Type 2 diabetes (T2DM) has increased disproportionately in Africa, South East Asia, Middle and Asia Pacific region. Interestingly, although we need more studies investigating T2DM Latin America, youth living these countries does not seem to have markedly.
Summary Context Vitamin D deficiency is common in urban Indians despite living the tropics and its public health consequences are enormous. However, 70% of India rural, data from rural subjects, who expected to have good sun exposure, scant. Objectives To determine population prevalence vitamin pregnant women adolescent girls, compare serum 25‐hydroxyvitamin (25OHD) status boys same families, seasonal differences 25OHD. Design A cross‐sectional study conducted over 18 months. Subjects random...
Hypovitaminosis D is common in India. In the present prospective partially randomised study of vitamin (D 3 ) supplementation during pregnancy, subjects were second trimester to receive either one oral dose 1500 μg (group 1, n 48) or two doses 3000 each and third trimesters 2, 49). Maternal 25-hydroxyvitamin (25(OH)D) at term, cord blood (CB) alkaline phosphatase (ALP), neonatal serum Ca anthropometry measured these forty-three non-supplemented mother–infant pairs (usual care). Median...
Incomplete differentiation of the anterior pituitary (AP) hormone-secreting cells can result in combined hormone deficiency (CPHD), which patients display deficiencies GH and at least one other AP hormone. The majority familial CPHD cases are due to mutations transcription factor PROP1 (Prophet Pit1). We have scanned for a large consanguineous Indian pedigree identified novel 13-bp deletion exon 2 that is predicted generate null allele. Assessment GH, TSH, gonadotropin, PRL levels homozygous...
Background: Extrahepatic portal vein obstruction has been shown to cause growth retardation in children, though literature is scant. No information available regarding the of these patients. Methods: To document presence this disease, we studied and nutrition 33 consecutive prepubertal Anthropometry, fasting hormone, insulin-like factor I levels were compared 22 well-nourished patients from group with 35 age-matched controls. Results: Mean ± SD height standard deviation score (-1.88 1.33)...
Abstract We assessed the effect of vitamin D supplementation on related biochemistry, infection and dentition infant. In a double-blind, placebo-controlled trial conducted in Lucknow, India (latitude 26°N), 230 mother –newborn pairs were randomised to receive, for 9 months, 3000µg/month oral 3 by (group A) or 10µg/d infant B) double placebo C). All babies received 15 min sun exposure (unclothed) during massage. Infants’ median 25-hydroxyvitamin (25(OH)D) was lower group C (median 45·3;...