A5057204077- Hemoglobinopathies and Related Disorders
- Pharmacological Effects and Toxicity Studies
- Pharmaceutical Practices and Patient Outcomes
- Pregnancy and Medication Impact
- Grief, Bereavement, and Mental Health
- CRISPR and Genetic Engineering
- Patient Safety and Medication Errors
- Animal Genetics and Reproduction
- Gender, Feminism, and Media
- Glycosylation and Glycoproteins Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Pharmaceutical studies and practices
- HIV/AIDS drug development and treatment
- Pharmacovigilance and Adverse Drug Reactions
- Genetically Modified Organisms Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Hematological disorders and diagnostics
- Iron Metabolism and Disorders
- Cannabis and Cannabinoid Research
- Drug-Induced Adverse Reactions
- HIV/AIDS Research and Interventions
- Palliative Care and End-of-Life Issues
- Digital Games and Media
- Opioid Use Disorder Treatment
- Blood Pressure and Hypertension Studies
Carolinas Medical Center
2014-2024
Atrium Medical Cente
2020
Levine Cancer Institute
2018-2019
University of Nebraska–Lincoln
2007
Prostate cancer progression can be predicted in human tumor biopsies by abundant hyaluronan (HA) and its processing enzyme, the hyaluronidase HYAL1. Accumulation of HA is dictated balance between expression levels synthases, enzymes that produce polymers, hyaluronidases, which process polymers to oligosaccharides. Aggressive prostate cells express 20-fold higher synthase HAS3, but mechanistic relevance this correlation has not been determined. We stably overexpressed HAS3 cells. Adhesion...
The impact of a focused education initiative to increase pharmacists' documentation clinical interventions is described.A was developed the consistency in order achieve pharmacy goals and demonstrate value services at Carolinas Medical Center Charlotte, North Carolina. Education provided through weekly newsletter publications, huddles, monthly staff meetings. Pharmacy specialists were tasked with providing examples activities that should be documented as interventions, reviewing selection...
Treatment-dose enoxaparin is not well studied in obese patients. Guidelines suggest that patients receiving therapy for acute venous thromboembolism (VTE) should receive a standard initial dose, 1 mg/kg, based on actual body weight. It possible this dosing strategy may be overestimated, leading to higher bleeding risk compared non-obese patients.To gather data regarding treatment and anti-Xa level monitoring who are guide dose adjustments.A single-center, retrospective chart review included...
Medications used to treat OUD have common metabolic pathways and pharmacodynamic properties that can lead drug-drug interactions (DDIs) may go unnoticed in the inpatient setting. The purpose of this study was identify frequency DDIs between medications prescribed for commonly medications.This a retrospective review orders buprenorphine, buprenorphine-naloxone, methadone potential DDIs. Adult inpatients with an order one these were included. Medication regimens evaluated throughout stay on...
Purpose: To compare the incidence of oversedation between oral and parenteral diphenhydramine therapy for treatment opioid-induced pruritus in patients with sickle cell disease vaso-occlusive crisis (SCD VOC). Methods: This retrospective, single-center, cohort study included greater than or equal to 18 years old admitted who received either intravenous pruritus. Patients were identified through ICD-9 ICD-10 codes from June 1, 2016 July 2017. Rates compared 2 formulations. Secondary endpoints...