A5101901183- Historical Studies of British Isles
- Scottish History and National Identity
- Reformation and Early Modern Christianity
- Irish and British Studies
- Monoclonal and Polyclonal Antibodies Research
- Medieval Literature and History
- Glycosylation and Glycoproteins Research
- American Constitutional Law and Politics
- Genomics and Chromatin Dynamics
- Education and Technology Integration
- EFL/ESL Teaching and Learning
- Historical Influence and Diplomacy
- Historical Economic and Social Studies
- Venomous Animal Envenomation and Studies
- Religious Tourism and Spaces
- Human Resource Development and Performance Evaluation
- Religious Education and Schools
- Higher Education Governance and Development
- Philippine History and Culture
- HER2/EGFR in Cancer Research
- Archaeology and Natural History
- Historical and Contemporary Political Dynamics
- Toxin Mechanisms and Immunotoxins
- Bacteriophages and microbial interactions
- Gun Ownership and Violence Research
University College Dublin
2002-2023
Cambridgeshire and Peterborough NHS Foundation Trust
2022
University of Cambridge
2009
Wellcome Sanger Institute
2004-2006
Research School for Medieval Studies
1998-2002
Rush University Medical Center
1997
Unilever (Netherlands)
1981
Unilever (India)
1980
The monocled cobra (Naja kaouthia) is among the most feared snakes in Southeast Asia due to its toxicity, which predominantly derived from long-chain α-neurotoxins. only specific treatment for snakebite envenoming antivenom based on animal-derived polyclonal antibodies. Despite lifesaving importance of these medicines, major limitations safety, supply consistency, and efficacy create a need improved treatments. Here, we describe discovery subsequent optimization recombinant human monoclonal...
McCafferty, John; Hoogenboom, Hennie; Chiswell, Dave; Mikecz, Katalin MD, PhD Author Information
Passive immunization using monoclonal antibodies will play a vital role in the fight against COVID-19. The recent emergence of viral variants with reduced sensitivity to some current and vaccines highlights importance broad cross-reactivity. This study describes deep-mining antibody repertoires hospitalized COVID-19 patients phage display technology B cell receptor (BCR) repertoire sequencing isolate neutralizing gain insights into early response. comprehensive discovery approach has yielded...
The future of training, particularly over the next 10–20 years, can usefully be examined within a broad framework which should, at least, include:
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How can we encourage and help managers to become more innovative in their problem‐solving decision‐making, so that the commitment of today's resources future leads achievement appropriate long‐term strategies for companies? It is inevitable this article attempt cover only a small area ground, it would be naive offer solutions which should situationally determined. However, I feel consideration given such important issues as:
Abstract Snakebite envenoming continues to claim many lives across the globe, necessitating development of improved therapies. To this end, human monoclonal antibodies may possess advantages over current plasma-derived antivenoms by offering superior safety and neutralization capacity. However, as new antivenom products need be polyvalent, i.e ., target multiple different snake species, without dramatically increasing dose or cost manufacture, such broadly-neutralizing. Here, we report...
Henry VIII's dissolution campaigns affected only about one-fifth of Irish mendicant houses. The Observant friars managed a staged withdrawal to the west and north island in face later Tudor closures. Drawing on lengthy history written Louvain 1617, this article explores how Franciscans responded 70-year, slow-motion monasteries. Observants continued be visibly active neighbourhood many former friaries were even allowed residence within walls by number new Protestant proprietors. friars'...
presume, at least his teaching on discernment was grounded in what God had taught him a direct manner Manresa?Yes, there historical precedent the Desert Fathers, but Ignatius's insights into were (almost) uniquely own.Not so, according to these chapters.O'Reilly shows that much Rules for Discernment can be found reading material, especially Vita Christi, Flos Sanctorum, and Contemptus Mundi.When it comes even trickier question of consolation without preceding cause, O'Reilly ranges more...