Weiguang Yu

ORCID: 0000-0003-4687-2624
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About
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Research Areas
  • Reconstructive Surgery and Microvascular Techniques
  • Colorectal Cancer Surgical Treatments
  • Colorectal and Anal Carcinomas
  • Gastric Cancer Management and Outcomes
  • Rheumatoid Arthritis Research and Therapies
  • Oral microbiology and periodontitis research
  • Medicinal Plants and Neuroprotection
  • Psychedelics and Drug Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Cannabis and Cannabinoid Research
  • Cancer-related molecular mechanisms research
  • Orthopedic Surgery and Rehabilitation
  • Surgical Sutures and Adhesives
  • Mycobacterium research and diagnosis
  • Knee injuries and reconstruction techniques
  • Forensic Toxicology and Drug Analysis
  • Colorectal Cancer Treatments and Studies
  • Genetic factors in colorectal cancer
  • Bone fractures and treatments

The First Affiliated Hospital, Sun Yat-sen University
2025

Sun Yat-sen University
2025

Shanxi Medical University
2024

Ministry of Public Security of the People's Republic of China
2024

Mudanjiang Medical University
2016-2022

Hebei Medical University
2010-2018

Third Hospital of Hebei Medical University
2010-2018

Breast cancer is one of the major malignancies with a mounting mortality rate in world. Long noncoding RNA (lncRNA) susceptibility candidate 2 (CASC2) has been identified to regulate initiation and progression multiple tumorous diseases according previous studies. However, its biological role rarely reported breast cancer. In present study, lncRNA CASC2 was found be significantly downregulated tissues cell lines using real-time quantitative PCR. Furthermore, gain-of-function assays...

10.3727/096504018x15199531937158 article EN cc-by-nc-nd Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 2018-03-10

Objective The optimal therapeutic strategy for metastatic microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) colorectal cancer (CRC) remains uncertain. This multicenter retrospective study compared the efficacy and safety of pembrolizumab monotherapy versus bevacizumab combined with modified FOLFOX6 (mFOLFOX6) in this molecularly defined population. Methods Consecutive patients MSI-H/dMMR CRC treated or plus mFOLFOX6 at two tertiary centers (2017–2024) were analyzed. Dual...

10.3389/fonc.2025.1570457 article EN cc-by Frontiers in Oncology 2025-04-04

Objective This study seeks to identify clinicopathological risk factors associated with tumor deposits (TD) development in stage I-III gastric cancer patients and construct a visualized predictive model for clinical application. Methods A retrospective cohort of 1,284 treated at the Affiliated Hospital Hebei University (September 2010–September 2022) was analyzed. Patients were stratified into training ( n = 963) validation 321) cohorts via simple randomization 3:1 ratio. Lasso regression...

10.3389/fmed.2025.1577569 article EN cc-by Frontiers in Medicine 2025-05-30

To investigate the toxicokinetic differences of 3,4-methylenedioxy-

10.12116/j.issn.1004-5619.2022.320201 article EN PubMed 2024-02-25

Objective To investigate the therapeutic effect of complete mesocolic excision (CME) for right colon cancer. Methods The data 47 cases cancer performed elective CME by same group surgeons between July 2012 and September 2014 at Mudanjiang University Hongqi Hospital General Surgery Department were analyzed retrospectively. Results Among with CME. The operation smoothly no vice injury. median number total lymph nodes retrieved was 18. Twelve (25.53%) stage III had positive in or...

10.3877/cma.j.issn.2095-3224.2016.02.14 article EN Chin J Colorec Dis (Electronic Edition) 2016-04-25

Objective To investigate the clinical efficiency of branch artery sural medial gastrocnemius muscle flap combine with nerve nutritional vessel axial.Methods From February 2006to March 2010,according to position and size soft tissue defects,the combined axial were desingned obtained repair 7 cases sofi defects upper-region tibial.The ranged from 8.0 cm × 12.0 10.0 cm.The pedicle branches 1.8-3.0 distribution 10.0-17.0 on distant popliteal fossa,and 2.0-5.0 back line.Results The outline...

10.3760/cma.j.issn.1001-2036.2011.05.006 article EN Zhonghua xianwei waike zazhi 2011-10-25

Objective To investigate the clinical efficiency of kid foot soft tissue defect with reverse flap cutaneous branch fibular artery combine sural nerve nutritional vessel axial. Methods From Feb. 2006 to 2009, according position and size defects, peroneal were desingned obtained repair 5 cases defects foot. The ranged from 8 cm × 7 18 10 cm. pedicle branches 1.7 3.0 distribution 4.5 8.0 on lateral malleolus. Results All flaps survived completely in 6 cases. outline function satisfactory during...

10.3760/cma.j.issn.1001-2036.2010.01.006 article EN Zhonghua xianwei waike zazhi 2010-02-25

Objective To investigate the methods and therapeutic effects of groin flap stylus recurrent branch radial artery for repair severely contracture first web space. Methods From March 2007 to six 2009,45 patients with space received treatment flaps flaps, 6 12 months clinical observation. Among then, 33 28 widening as well functional reconstruction thumb abduction. Results Most healed by intention but also distal necrosis 3 1 flap. And weth all were more than 90% comparison....

10.3760/cma.j.issn.1001-2036.2010.02.004 article EN Zhonghua xianwei waike zazhi 2010-04-25

Oblective To investigate the surgical results of groin flap transfer to treat severe first web contracture in children caused by firework explosion.Methods From 2007 2009 nine with firewoik explosion were treated transfer.All patients male.Their ages ranged from 7 14 years,with an average 11.4 years.The surgery was carried out two stages.In stage raised and sewed dorsum second metacarpal base a skin tube pedicle,Six weeks later at stage,flap pedicle divided widened.The bow-shaped wire keep...

10.3760/cma.j.issn.1005-054x.2010.03.017 article EN Zhonghua shouwaike zazhi 2010-06-10

This study was aimed to analyze the application value of filtered back‐projection (FBP) reconstruction algorithm computed tomography (CT) images in laparoscopic‐assisted distal gastrectomy. In this study, 56 patients with gastric cancer were selected as research subjects and randomly divided into control group (CT‐guided laparoscopic radical gastrectomy) observation gastrectomy FBP algorithm), 28 each group. Fourier transform iterative introduced for comparison, finally, postoperative...

10.1155/2022/2464640 article EN cc-by Contrast Media & Molecular Imaging 2022-01-01
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