A5054851336- Microbial Metabolic Engineering and Bioproduction
- Fault Detection and Control Systems
- Polyamine Metabolism and Applications
- Spectroscopy and Chemometric Analyses
- Mineral Processing and Grinding
- GABA and Rice Research
- Biofuel production and bioconversion
- Protein Hydrolysis and Bioactive Peptides
- Mitochondrial Function and Pathology
- Water Quality Monitoring and Analysis
- Control Systems and Identification
- Advanced Control Systems Optimization
- Structural Health Monitoring Techniques
- Metabolomics and Mass Spectrometry Studies
- Blind Source Separation Techniques
- Metabolism and Genetic Disorders
- Genomics and Phylogenetic Studies
- Sensory Analysis and Statistical Methods
- Process Optimization and Integration
- Catalysis for Biomass Conversion
- Fluid Dynamics and Mixing
- Medical Image Segmentation Techniques
- Advanced Chemical Sensor Technologies
- Bioinformatics and Genomic Networks
- Gene Regulatory Network Analysis
East China University of Science and Technology
2010-2020
East China University of Technology
2020
University of Science and Technology Beijing
2019
State Key Laboratory of Bioreactor Engineering
2013-2018
Dayeh University
2016
Newcastle University
2011
University of Minnesota
2009
University of Minnesota, Duluth
2007
The University of Texas at Austin
2004-2005
South China University of Technology
2000
Pichia pastoris is one of the most important cell factories for production industrial enzymes and heterogenous proteins. The genome-scale metabolic model high quality crucial comprehensive understanding P. metabolism. In this paper, we upgraded based on combination latest genome annotations literatures. Then performance new was evaluated using Cobra Toolbox v2.0. Compared with recently published iMT1026, reaction number in iRY1243 increased from 2035 to 2407 metabolite 1018 1094....
In this paper, we show that the consistency of closed-loop subspace identification methods (SIMs) can be achieved through innovation estimation. Based on analysis, a sufficient condition for new proposed SIM is given. A consistent estimate Kalman gain under conditions also provided based algorithm. multi-input-multi-output (MIMO) simulation shows it condition, when traditional SIMs fail to provide estimates.
Pichia pastoris is a popular recombinant protein expression system for its accessibility of efficient gene manipulation and high production. Sufficient supply precursors, energy, redox cofactors crucial In our present work, we found that the addition glutamate improved β-galactosidase (β-gal) production by P. G1HL. To elucidate impacts on central metabolism in detail, combined 13C-assisted metabolomics 13C metabolic flux analysis was conducted based LC–MS/MS GC–MS data. The pool sizes...
The estimation of the prediction region partial least squares (PLS) is necessary in many engineering applications. However, research this area focuses on intervals only. In work, a new recursive formulation PLS proposed to facilitate calculation Jacobian matrix estimated coefficient matrix. Furthermore, computational complexity analysis indicates that algorithm O ( m 2 N + mpN mN 3 4 ) per number component. multivariate obtained through local linearization. provides one way obtain PLS....
In this paper, we propose a vessel segmentation method in brain CT angiography. Its main idea is to remove bones by bone-to-bone elimination procedure between two series of images, instead time-consuming registration algorithm. Some pixels may be removed mistake during bone removal procedure. We invent the conditional dilation restore lost pixels. Whenever region identified, change its outer boundary background values so that later growing can find out whole structure. Since computation no...
In this paper, after investigation of the possibility misidentification faults with traditional structured residuals approaches, a new optimal design criterion for fault isolation is proposed. To maximize ability, matrix directions has been designed. Each them insensitive to one subset while being most sensitive remaining ones. The maximum all in each row then selected identification. After faulty sensor identfied, normal measurements are reconstructed through likelihood estimation. utility...
Abstract Several models for end-point carbon prediction of BOF(Basic Oxygen Furnace) based on off-gas analysis were studied in this paper. The advantages and disadvantages the integral model, exponential decay model cubic fitting analyzed respectively. Based characteristics decarburization rate curve, a new was established by introduction correction algorithm. principle proposed involves applying curve descending gradient historical heats to obtain average reference efficiency coefficient...