A5037192572- Peripheral Artery Disease Management
- Vascular Procedures and Complications
- Cerebrovascular and Carotid Artery Diseases
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Renal and Vascular Pathologies
- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Infectious Aortic and Vascular Conditions
- Diagnosis and Treatment of Venous Diseases
- Aortic Disease and Treatment Approaches
- Vascular anomalies and interventions
- Dermatologic Treatments and Research
- Pelvic and Acetabular Injuries
- Diabetic Foot Ulcer Assessment and Management
- COVID-19 and healthcare impacts
- Trauma and Emergency Care Studies
- Clinical practice guidelines implementation
- Acute Ischemic Stroke Management
- Colorectal Cancer Surgical Treatments
- Cardiovascular and exercise physiology
- Coronary Interventions and Diagnostics
- Lipoproteins and Cardiovascular Health
- Retirement, Disability, and Employment
- Ocular Diseases and Behçet’s Syndrome
University Hospital of Wales
2022-2025
Cardiff and Vale University Health Board
2024
University of Birmingham
2018-2022
University Hospitals Birmingham NHS Foundation Trust
2021-2022
Worcestershire Royal Hospital
2013-2021
Solihull Hospital
2017-2021
Heart of England NHS Foundation Trust
2017-2020
University Hospital Coventry
2019
Cancer Research UK Clinical Trials Unit
2018-2019
Russells Hall Hospital
2017-2018
Severe limb ischaemia (SLI) is defined as the presence of rest pain and/or tissue loss secondary to lower extremity atherosclerotic peripheral arterial disease. The superficial femoral and popliteal arteries are most commonly diseased vessels in such patients being increasingly treated using endovascular revascularisation techniques. However, it currently unknown whether drug-eluting stents drug-coated balloons confer additional clinical benefits over more established techniques plain bare...
The Bypass versus Angioplasty in Severe Ischaemia of the Leg-2 (BASIL-2) randomised controlled trial has shown that, for patients with chronic limb threatening ischaemia (CLTI) who require an infrapopliteal (IP) revascularisation a vein bypass (VB) first strategy led to 35% increased risk major amputation or death when compared best endovascular treatment (BET) strategy. study aims are place BASIL-2 within context CLTI patient population as whole and investigate generalisability outcome data.
Abstract Objective To determine which primary endovascular revascularisation strategy represents the most clinically effective treatment for patients with chronic limb threatening ischaemia who require femoro-popliteal, or without infra-popliteal, revascularisation. Design Three arm, open label, pragmatic, multicentre, randomised, phase 3 superiority trial (BASIL-3). Setting 35 UK NHS vascular units. Participants Patients required Interventions were randomly assigned (1:1:1) to...
ObjectiveThe Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL)-2 trial enrolled participants with chronic limb threatening ischaemia who required an infrapopliteal, or without a femoropopliteal, revascularisation procedure to restore perfusion. Participants randomised vein bypass (VB) first strategy were over one third more likely than those best endovascular treatment (BET) die from any cause during median follow up 40.0 (interquartile range 20.9, 60.6) months. The aim...
BackgroundBypass surgery (BS) remains the gold standard revascularization strategy in patients with chronic limb-threatening ischemia (CLTI) owing to infrainguinal disease. The Bypass versus Angioplasty for Severe Ischaemia of Leg (BASIL)-1 trial showed that, CLTI who survived 2 years or more, BS resulted better clinical outcomes. Despite this finding, there has been an increasing trend toward endovascular-first approach CLTI. Our aim was investigate whether changes practice have impacted...
Large language models and artificial intelligence (AI) based chatbots have brought new insights in healthcare, but they also raise major concerns. Their applications vascular surgery scarcely been investigated to date. This international survey aimed evaluate the perceptions feedback from surgeons on use of AI surgery. open e-survey comprised 50 items that covered participant characteristics, their surgery, user experience. The study was designed accordance with Checklist for reporting...
Conservative management of an aortic graft infection is defined as "the nonresectional treatment that has established infection." Incidence infections 0.5 to 5% and the estimated mortality rate from ranges 8 27%. We present case a 73-year-old male patient with infected abdominal following emergency ruptured aneurysm repair. Postemergency repair, he developed ischemic colitis sigmoid colon perforation leading fecal peritonitis secondary sepsis. He large infective collection within sac growing...
The Bypass versus Angioplasty in Severe Ischaemia of the Leg-2 (BASIL-2) randomised controlled trial has shown that, for patients with chronic limb threatening ischaemia (CLTI) who require an infrapopliteal (IP) revascularisation a vein bypass (VB) first strategy led to 35% increased risk major amputation or death when compared best endovascular treatment (BET) strategy. study aims are place BASIL-2 within context CLTI patient population as whole and investigate generalisability outcome data.
Background Chronic limb-threatening ischaemia with ischaemic pain and/or tissue loss. Objective To examine the clinical and cost-effectiveness of a vein bypass-first compared to best endovascular treatment-first revascularisation strategy in preventing major amputation or death. Design Superiority, open, pragmatic, multicentre, phase III randomised trial. Setting Thirty-nine vascular surgery units United Kingdom, one each Sweden Denmark. Participants Patients chronic due atherosclerotic...
INTRODUCTION Anecdotally, surgeons claim splenic flexure mobilisation is more difficult in male patients. There have been no scientific studies to confirm or disprove this hypothesis. The implications colorectal surgery could be profound. aim of study was assess quantitatively whether there an anatomical difference the position between men and women using computed tomography (CT). METHODS Portal venous phase CT performed for preoperative assessment malignancy analysed hospital picture...