The present study was carried out to investigate the nephroprotective effect of ethanolic extract Allium saralicum R.M. Fritsch (ASRMF) in mice. Thirty-five male mice were divided into five groups (n=7). Group 1 (positive control) received mL/kg olive oil intraperitoneally (i.p.) and 0.5 mL distilled water orally; 2 (negative CCl4 (50% oil, mg/kg; i.p.); Groups 3, 4 5 200, 800 1600 ?g/kg ASRMF extract, respectively. renal volume cortex increased by 55% 62% (p?0.001) following administration,...

There is growing concern that some cytotoxic regimens for cancer adversely affect spermatogenesis and male fertility. Increasing evidence demonstrated melatonin has beneficial impacts on reproductive processes; however, whether can protect against bleomycin, etoposide, cisplatin (BEP) chemotherapy regimen-induced testicular toxicity, remains obscure. The present study aimed to explore the effect of BEP-evoked injury in rats. Adult Wistar rats (n = 10/group) were intraperitoneally (i.p.)...

Impaired spermatogenesis and male infertility are common consequences of chemotherapy drugs used in patients with testicular cancer. The present study investigated the effects sodium alginate (NaAL) on toxicity caused by bleomycin, etoposide, cisplatin (BEP). Rats group 1 received normal saline, while groups 2 3 were treated 25 50 mg/kg NaAL, respectively. Group 4 was a 21-day cycle BEP (0.5 5 cisplatin), 6 regimen plus Then, sperm parameters, testosterone levels, histopathology...

Objective: To evaluate the effect of Heracleum persicum L. against gentamicin-induced nephrotoxicity in rats. Methods: Thirty-six Wistar rats were divided into 6 groups including control (normal saline), gentamicin (80 mg/kg/d for 10 d), (750 mg/kg/d), and (10 d) + extract at three different doses (250, 500, 750 40 d). Urine creatinine, urea, protein, albumin levels determined. In addition, serum sodium, potassium, cytokines (TNF-α, IL-1β, IL-6, IL-10), glutathione peroxidase activity, total...

Abstract Background Lovebird ( Agapornis personatus ) is a monotypic species of bird the lovebird genus in parrot family Psittaculidae and order Psittaciformes . Objectives The present study was designed to investigate histology immunohistochemistry pancreas lovebird. Methods Totally, three adult birds were used. assessed using histological immunofluorescent staining detect insulin, glucagon, somatostatin, pancreatic polypeptide (PP) neuropeptide Y (NY). Results exocrine composed pyramidal...

ABSTRACT This study investigates the gross morphological and morphometric characteristics of thoracic lumbar intervertebral discs (IVDs) in guinea pigs, utilising micro‐CT imaging anatomical dissection. The findings reveal 13 six IVDs were identified, with transitioning from rounded forms at T1–T3 to triangular heart‐shaped structures T4–T13, while exhibited a consistently flattened heart shape. Morphometric analysis revealed statistically significant differences, being larger lateral...

Objective: To examine the protective effects of green-synthesized zinc oxide nanoparticles with Berberis vulgaris L. fruit aqueous extract (BVZnONPs) on cyclophosphamide (CP)-induced nephrotoxicity in Wistar rats. Methods: 35 Adult male rats were divided into 5 groups: normal, BVZnONPs (20 mg/kg), CP (100 and 2 co­treatment groups receiving (10 20 mg/ kg). All treatments administered intraperitoneally for 28 days. Serum levels antioxidant enzymes (catalase, superoxide dismutase, glutathione...

Trachyspermum ammi (T. ammi) has been used in folk medicine as anti-inflammatory, antipyretic, antibacterial, antifungal agent. The present study was conducted to investigate the protective effect of essential oil against CC14- induced nephrotoxicity mice. Thirty-five mice were divided into five groups follows; positive control received olive 1 mL/ kg/ip, negative CC14 mg/kg/ip + 0.5 mL distilled water orally and tree treatment which similar 200, 800 1600 µg/kg T. oil, respectively. All...

This study provides some comprehensive osteometric and morphologic descriptions of the skull region Markhoz goat. Totally, 17 parameters eight skulls goat were measured expressed as mean ± SD. A length 18.67 0.66, a cranial 11.1 0.38, facial 10.23 0.76, index 47.77 1.96, 54.04 2.29, 100.77 6.85 foramen magnum 89.32 14.1 recorded. Morphologically frontal bone did not constitute caudal extent surface; rather it was formed by parietal bone. There two supraorbital foramina in both sides. The...

Anabolic androgenic steroids (AAS) such as oxymetholone (OM) used for athletic enhancement, but increased free radicals damage and changes in hormonal levels, lead to serious irreversible organ damage. Vaccinium arctostaphylos(V. arctostaphylos( has been demonstrated have antioxidant antiinflammatory effects. The aim of present study was investigate V. arctostaphylos effect on OM-induced oxidative injury mouse testis sperm parameters. In this experimental study, 30 BALB/c mice were divided...

Background and Objectives: Diabetes is a chronic metabolic disorder that can effectively influences male reproductive performance. The present study was conducted to investigate the protective effects of Solanum lycopersicum essential oil (SL) on diabetes-induced testicular injuries. Materials Methods: Adult rats were randomly allocated into five groups (n = 8 in each group). 1: control; 2: diabetic; 3: diabetic + 30 mg/kg SL oil; 4: 90 5: 270 extract. induced by single dose streptozotocin...

The aim of this study was to investigate the morphostructure lingual papillae in Markhoz goat.Tissue samples were taken from dorsal surfaces apex, body and root tongues five adult goats.After routine procedure preparation, observed under scanning electron microscope.Three mechanical tow gustatory types seen.Filiform distributed on surface anterior two-thirds tongue.A bulb-like structure formed basal portion papilla.Between six eight secondary with sharp pointed tips emerged at base filiform...

Abstract Study question Is there a potential for sodium alginate (NaAL) to alleviate the damage induced by BEP chemotherapy in testicular cells and spermatogenesis process? Summary answer Administering NaAL at doses of 25 50 mg/kg demonstrates protective effects against BEP-evoked toxicity through modulation nitro-oxidative stress, inflammation, apoptosis. What is known already Testicular tumours are prevalent malignancy affecting young males aged 20 35 years. The globally accepted cancer...

The present study was designed to investigate the protective effects of hydroalcoholic extract Ashrasi date palm (ADP) on diabetes-induced testicular injuries. Adult male rats were randomly allocated into five groups (n = 8 in each group): 1: control; 2: diabetic; 3: diabetic + 30 mg/kg ADP extract; 4: 90 and 5: 270 extract. Diabetes induced by a single dose streptozotocin (55 mg/kg) intraperitoneally. Testicular changes assessed quantitatively using stereological method followed measuring...

Abstract The present investigation was conducted to investigate the histology, immunohistochemistry, stereology, and ultrastructure of small intestine in common pheasant ( Phasianus colchicus ) using light scanning electron microscopy (SEM). Ten birds were included study. obtained findings revealed that three parts namely duodenum, jejunum, ilium constituted four layers from innermost outermost including tunica mucosa, submucosa, muscularis, serosa. All had simple columnar epithelium with...

Abstract The morphology and histological structure of two adult Brandt’s hedgehog, Paraechinus hypomelas , (Brandt, 1836) tongue were examined by light scanning electron microscopy. On the dorsal surface tongue, three types papillae observed: filiform, fungiform vallate papillae. Apex corpus as well lateral covered with numerous filiform bifurcated tip, while epithelium lining ventral lingual was free from Discoid shape scattered over entire apex, uniformly between ones without regional...