A5023496847- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Systemic Sclerosis and Related Diseases
- Inflammatory Myopathies and Dermatomyositis
- Salivary Gland Disorders and Functions
- Eosinophilic Disorders and Syndromes
- Systemic Lupus Erythematosus Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Autoimmune Bullous Skin Diseases
- Tuberculosis Research and Epidemiology
- Mast cells and histamine
- Psoriasis: Treatment and Pathogenesis
- Bone health and osteoporosis research
- Sarcoidosis and Beryllium Toxicity Research
- Fungal Infections and Studies
- Academic Research in Diverse Fields
- Diabetes and associated disorders
- Nutrition and Health in Aging
- Antifungal resistance and susceptibility
- Bone fractures and treatments
- Hip and Femur Fractures
- Infectious Diseases and Tuberculosis
- Bone and Joint Diseases
- Chronic Disease Management Strategies
Instituto Politécnico da Guarda
2020-2024
Centre for Health Technology and Services Research
2024
Universidade do Porto
2024
NIHR Leeds Musculoskeletal Biomedical Research Unit
2024
University of Leeds
2024
Administração Regional de Saúde de Lisboa e Vale do Tejo
2024
Unidade Local de Saúde da Guarda EPE
2020-2023
Fundação Educacional D. André Arcoverde
2009
Dear Editor, anti-Ku antibodies (abs) have been associated with several CTD, mainly SLE and inflammatory myositis. However, abs are rare, just a few studies small number of patients focused on their clinical correlates [1, 2]. Spielmann et al., in study 42 positive patients, identified autoantibody biomarkers two CTD subsets, rarely overlapping, implications for management: anti-Ku-positive elevated creatine kinase (CK) levels having high risk interstitial lung diseases (ILDs), anti-dsDNA...
Relata-se um caso de esporotricose em cão da raça Boxer, macho, com seis anos, encaminhado para uma consulta por causa massa na região nasal e dispneia. Após o exame físico, animal foi internado a realização citologia, histologia radiografia. Nos exames citológico radiográfico, não foram constatadas alterações que justificassem Na histologia, observou-se presença granuloma contendo dois esporos Sporothrix schenckii. Foi realizado tratamento itraconazol 5mg/kg BID 60 dias. esse período,...
Introduction The presence of another rheumatological condition in patients with systemic sclerosis (SSc) is not uncommon. To report a case patient SSc-RA overlap and perform review the cases re-ported literature. Material Methods A chart present was performed. After, we performed literature search MEDLINE, EMBASE Cochrane databases. Results We included 26 articles. Sixty-three were reviewed, 51 female mean age 45.03 years at time first diagnosis. diagnosed limited cu-taneous SSc. Regarding...
Objective: To develop evidence-based recommendations for the non-pharmacological and pharmacological management of Raynaud’s phenomenon (RP) digital ulcers (DUs) in patients with systemic sclerosis other immune- mediated connective tissue diseases (CTDs). Methods: A task force comprising 21 rheumatologists, 2 surgeons (vascular plastic), nurses, 1 patient representative was established. Following a systematic literature review performed to inform recommendations, statements were formulated...
To identify risk factors for SARS-CoV-2 infection and severe/critical COVID-19, to assess the humoral response after COVID-19 in these patients.
<h3>Background:</h3> We recently created PORTRESS, the Portuguese registry of Sjögren's Disease (SjD), as a specific module embedded within Registry Rheumatic Diseases (Reuma.pt). <h3>Objectives:</h3> To characterise largest nationwide cohort SjD patients. <h3>Methods:</h3> included patients with clinical diagnosis SjD, registered in PORTRESS up to November 2023. Demographic, clinical, treatment and patient-reported outcomes (PROs) data were collected. Variables compared according parametric...
<h3>Background:</h3> One of the most impacting complications Sjögren's disease (SjD) is development lymphoma, reported to occur in around 5-10% patients with SjD. There have been multiple studies proposing possible risk factors for lymphoma <h3>Objectives:</h3> Our goal assess prevalence a nationwide cohort SjD and identify potential its occurrence these patients. <h3>Methods:</h3> Multicentre retrospective study, including clinical diagnosis SjD, registered PORTRESS — Portuguese Registry up...
Psoriatic arthritis (PsA) and psoriasis (Pso) are highly heterogeneous inflammatory diseases. Multidisciplinary approaches associated with improved results in both musculoskeletal (MSK) skin manifestations. We describe the experience main diagnostic therapeutic outcomes of one largest longest-running Rheumatology/Dermatology multidisciplinary PsA Clinic.
<h3>Background</h3> The Systemic Lupus Erythematosus Disease Activity Score (SLE-DAS) has been recently developed and validated, providing improved accuracy sensitivity for changes in SLE disease activity comparison to Index 2000 (SLEDAI-2K) <sup>[1]</sup>. New recommendations standardize the Physician Global Assessment (PGA) scoring may improve its reliability <sup>[2]</sup>. <h3>Objectives</h3> To assess intra- interrater of SLE-DAS, SLEDAI-2K PGA measuring activity. <h3>Methods</h3> A set...
Background: Rheumatoid Arthritis (RA) is a chronic systemic inflammatory disorder with high cardiovascular (CV) risk due to both classic and specific disease factors. According EULAR’s recommendations, all patients should carry out an assessment of their CV risk, however, there are no evaluation algorithm’s for RA. Objectives: To assess the efficacy predict in RA using Systematic Coronary Risk Evaluation model (SCORE), Modified SCORE (mSCORE), Framingham Score (FRS), (mFRS) American College...
Background: Inflammatory joint disorders have an increased cardiovascular (CV) risk when compared with general population. In 2009, the EULAR task force advocated use of a 1.5 multiplication factor for these prediction models in Rheumatoid Arthritis patients specific characteristics. The SCORE was not modified Psoriatic (PsA) and Spondyloarthritis (SpA) accordance present recommendations. Objectives: To assess accuracy several CV algorithms to predict event determine its sensibility...
Inclusion body myositis and muscular granulomas – a rare finding Filipe Cunha Santos, Santos Rheumatology Department, Local Health Unit of Guarda, Portugal Correspondence to: Serviço de Reumatologia, Unidade Saúde da Avenida Rainha Dona Amélia, 6300-858 Portugal. E-mail: filipe.santos@ulsguarda.min-saude.pt https://orcid.org/0000-0003-4714-0353 Search for other works by this author on: Oxford Academic PubMed Google Scholar Ana Sofia Pinto, Pinto https://orcid.org/0000-0002-4026-8357 Sara...
Background: Infectious complications are a major concern among immunosuppressed patients. In an attempt to ameliorate these, EULAR released updated version of their recommendations for vaccinations in patients with rheumatic diseases. These should resonate even further, since our deliberately order achieve remission. 2018, Risk Assessment Clinic (IRAC) was created centre address these issues and prepare biological therapy. This work summarizes experience. Objectives: Compare vaccination rate...
Abstract Purpose Acute anterior uveitis (AAU) is one of the most common extra‐articular manifestations spondyloarthritis (SpA), causing significant burden in quality life (QoL). Golimumab (GLM) a tumor necrosis factor‐inhibitor proven to be effective and safe SpA. The GO‐EASY Study provided evidence that GLM decreases AAU occurrence rate Our aim study impact change vision‐related (VR) QoL subjects with SpA past or current AAU. Methods Ongoing prospective multicentre observational (including...
Background Anti-Ku antibodies are rare among patients with Connective Tissue Diseases (CTD) (1). Their potential role as a disease biomarker is not well established. Objectives To identify subgroups of anti-Ku positive according to their spectrum anti-nuclear antibody (ANA) specificities and analyze clinical analytical features. Methods Multicenter, cross-sectional study patients, irrespective diagnosis, followed at eight Rheumatology outpatient clinics. Patients were spontaneously...
Background: In the most recent European League Against Rheumatism (EULAR) cardiovascular risk reduction recommendations 1 , use of SCORE algorithm has been advocated as a useful tool to identify an increased 10-year first fatal atherosclerotic event. Even though validated inflammatory disease-specific CV score algorithms are still lacking, EULAR task force 1.5 multiplication factor for RA, but not clear other diseases. Objectives: To assess accuracy several predict event and determine its...