A5026719250- Bacterial Infections and Vaccines
- Discourse Analysis and Cultural Communication
- X-ray Diffraction in Crystallography
- Sociopolitical Dynamics in Russia
- Peptidase Inhibition and Analysis
- Immune Response and Inflammation
- Pneumonia and Respiratory Infections
- Crystallization and Solubility Studies
- Sperm and Testicular Function
- Glutathione Transferases and Polymorphisms
- Urinary Bladder and Prostate Research
- Genomics, phytochemicals, and oxidative stress
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Language, Communication, and Linguistic Studies
- Signaling Pathways in Disease
- Russian Literature and Bakhtin Studies
- Escherichia coli research studies
- Bacteriophages and microbial interactions
- Amoebic Infections and Treatments
- Adenosine and Purinergic Signaling
- Hormonal and reproductive studies
- International Human Rights and Reproductive Law
- Education, Literature, Philosophy Research
- Congenital heart defects research
- Regional Socio-Economic Development Trends
Saint Petersburg Mining University
2025
Ural State Medical University
2023
Chelyabinsk State Medical Academy
2023
Federal Research Center of Fundamental and Translational Medicine
2023
Sechenov University
2023
Peoples' Friendship University of Russia
2023
National Research Tomsk State University
2016-2022
Tomsk Polytechnic University
2022
Institute of Russian Literature
2019
Siberian Federal University
2019
Trumenba (bivalent rLP2086) is a vaccine licensed for the prevention of meningococcal meningitis disease caused by Neisseria meningitidis serogroup B (NmB) in individuals 10–25 years age USA. The composed two factor H binding protein (fHbp) variants that were recombinantly expressed Escherichia coli as native lipoproteins: rLP2086-A05 and rLP2086-B01. was shown to induce potent bactericidal antibodies against broad range NmB isolates expressing fHbp different sequence from antigens. Here, we...
Carboxypeptidase D (CPD) is a recently discovered metallocarboxypeptidase that predominantly located in thetrans-Golgi network (TGN), and also cycles between the cell surface TGN. In present study, intracellular distribution of CPD was examined AtT-20 cells, mouse anterior pituitary-derived corticotroph. CPD-containing compartments were isolated using antibodies to cytosolic tail. The immunopurified vesicles contained TGN proteins (TGN38, furin, syntaxin 6) but not lysosomal or plasma...
Duck gp180 was previously identified by its ability to bind the preS envelope protein of duck hepatitis B virus particles (Kuroki, K., Cheung, R., Marion, P. L., and Ganem, D. (1994) <i>J. Virol.</i> 68, 2091–2096). Cloning sequencing cDNA revealed that it is a polyprotein with three carboxypeptidase-like domains Eng, F., Ishikawa, T., Turck, C., Harada, (1995)<i>J. Biol. Chem.</i> 270, 15022–15028). To evaluate enzymatic properties this protein, soluble 170-kDa form (gp170) lacking...
Over the past few years, higher education system has undergone radical transformations. The aim of this paper is to analyze a retrospective reflection on experience forced digitalization in pandemic and post-pandemic periods. One promising methods assessing changes their impacts conduct longitudinal sociological research. methodology study consists several modules: 1. literature review; 2. formation summary; 3. survey period; 4. 5. an analysis transformation attitudes toward distance...
A rat testicular Mu-class glutathione<i>S</i>-transferase (GST) resolved by reversed-phase high performance liquid chromatography cross-reacted with peptide sequence-specific antisera raised against the human hGSTM3 subunit. Electrospray ionization mass spectrometry indicated that this GST subunit (designated rGSTM5 in report) has a significantly greater molecular (26,541 Da) than other subunits. The mouse homologue (mGSTM5 subunit) was also identified and characterized electrospray...
Carboxypeptidase D (CPD) contains three domains with homology to other metallocarboxypeptidases. To further characterize the various domains, we constructed a series of point mutants critical active site Glu duck CPD converted Gln. The proteins were expressed in baculovirus system, purified homogeneity, and characterized. Point mutations within both first second eliminated enzyme activity, indicating that third domain is inactive toward dansyl-Phe-Ala-Arg. removed only C-terminal Lys or Arg...
Е.Г.Новикова Ф.М.ДОСТОЕВСКИЙ В ЯПОНСКИХ КОМИКСАХ 1 Аннотация.В статье впервые предпринято специальное литературоведческое исследование японских комиксов (манга), созданных по мотивам романов Ф.М.Достоевского «Преступление и наказание» «Братья Карамазовы».Методологической основой исследования стала концепция межсемиотического перевода, восходящая к трудам Р.О.Якобсона.В работе показано, что, в отличие от доминирующей американском комиксе стратегии доместикации, японская культура стремится...
Oxidative stress considered to be the main cause of male infertility. Surgical treatment varicocele and elimination inflammatory process in accessory glands can help reduce level oxidative stress, however, most cases, antioxidant therapy is additionally prescribed. Currently, much attention paid regulatory peptides as a component due their antioxidant, anti-inflammatory immunomodulatory properties.To evaluate efficiency complex antimicrobial cytokines Superlymph for infertility associated...
The research is devoted to the problems of language adaptation Russian émigré community (1917-1940) abroad. It conducted in framework sociology literature, therefore, sociological terminology and definitions are used. considered context notions «assimilation» «denationalization» a particular historical period. novelty investigation consists studying as an object special reflection for literary emigration «1-st wave» its creative instrument. tries rethink role native language, functions...
ПРОБЛЕМАТИКА ПЕРЕВОДА В ПРОГРАММЕ ДЕКОНСТРУКЦИИ ЖАКА ДЕРРИДА статье исследуется вопрос о роли и месте проблематики перевода в программе деконструкции Жака Деррида, его изучение является целью данного исследования.Научная новизна исследования обусловлена тем, что философия Ж. Деррида предельно редко становится предметом специального анализа.Показано, основе размышлений переводческой проблематике лежит библейский миф вавилонском столпотворении; доказывается
BACKGROUND: Increasing the efficacy of treatment patients with chronic prostatitis / pelvic pain syndrome remains an urgent problem modern urology.
 AIM: The aim study is to evaluate clinical rectal suppositories oxidized dextran in syndrome.
 MATERIALS AND METHODS: 52 were treated (mean age 33.1 1.7 years). divided into 2 groups. Patients 1st group (n = 25) received form for 50 days according following scheme: first 10 days, 1 suppository at night, daily; next 40 every other day....
The question of the impact chronic prostatitis on male fertility remains debatable. In our study, we proved that inflammation prostate affects characteristics a man’s ejaculate. inflammatory process negatively reproductive men all ages, however, in older age group, its clinical and laboratory manifestations are most pronounced.
Томский государственный университет