A5063368654- Venous Thromboembolism Diagnosis and Management
- Neural dynamics and brain function
- Inflammatory Biomarkers in Disease Prognosis
- Medicinal Plants and Neuroprotection
- Adrenal and Paraganglionic Tumors
- Musculoskeletal synovial abnormalities and treatments
- Neuroscience and Neural Engineering
- Alzheimer's disease research and treatments
- Traditional Chinese Medicine Analysis
- Neuroinflammation and Neurodegeneration Mechanisms
- EEG and Brain-Computer Interfaces
- Tryptophan and brain disorders
- Medicinal Plants and Bioactive Compounds
- Flavonoids in Medical Research
- Thyroid Cancer Diagnosis and Treatment
- Functional Brain Connectivity Studies
- Barrier Structure and Function Studies
- Bioactive Compounds and Antitumor Agents
- Immune cells in cancer
- Pharmacological Receptor Mechanisms and Effects
- Cholesterol and Lipid Metabolism
- Cardiac, Anesthesia and Surgical Outcomes
- Adenosine and Purinergic Signaling
- Chronic Lymphocytic Leukemia Research
- Diet and metabolism studies
The First Affiliated Hospital, Sun Yat-sen University
2023-2025
Sun Yat-sen University
2023-2025
Army Medical University
2022-2025
Daping Hospital
2022-2025
Capital Medical University
2025
Beijing Friendship Hospital
2025
National Clinical Research Center for Digestive Diseases
2025
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2024
University of Electronic Science and Technology of China
2018-2024
Chengdu University of Traditional Chinese Medicine
2020-2024
Baicalin (BA), a multi-target neuroprotective agent, has poor solubility resulting in low bioavailability. In this study, multidrug-loaded liposomes were prepared by encapsulating BA, borneol (BO) and cholic acid (CA) to prevent ischemic stroke. BBC-LP administered intranasally (i.n.) deliver into the brain for neuroprotection. Finally, potential mechanism of BBC treating stroke (IS) was explored network pharmacology. reverse evaporation method, encapsulation efficiency (EE) optimized 42.69%...
To investigate the association between inflammatory indices-systemic immune-inflammation index (SII), monocyte-lymphocyte ratio (MLR), neutrophil-lymphocyte (NLR), platelet-lymphocyte (PLR) and preoperative deep vein thrombosis (DVT) in patients undergoing total joint arthroplasty (TJA). We created receiver operator characteristic (ROC) curve using ratios of SII, MLR, NLR, PLR to DVT before TJA, divided enrolled into groups based on cut-off value, then analyzed risk factors for TJA...
Baicalin (BA) is widely used in the treatment of cerebral ischemia-reperfusion injury (CIRI). The key to treating encephalopathy increase amounts drugs entering brain. Borneol-baicalin liposome (BO-BA-LP) was prepared previous research based on characteristics borneol (BO) promoting drug brain entry. In this study, effect BO-BA-LP improving blood-brain barrier (BBB) integrity researched. Results showed may ability BA penetrate cell membrane vitro. Pharmacokinetic results could concentrations...
Tobacco use has been confirmed to be a risk factor for postoperative complications, but the impact of smoking on adverse outcomes following thyroidectomy remains largely unknown. Using data spanning 2016–2020 from National Inpatient Sample, patients aged ≥ 18 years who underwent thyroid malignancy or other disorders were identified and classified into two groups: current smokers non-smokers. We compared outcome variables between groups via univariate analysis adjusted multivariate logistic...
Given the increasing prevalence of obesity, white-to-beige adipocyte conversion has attracted interest as a target for obesity treatment. Gamma-aminobutyric acid (GABA) treatment can reduce but underlying mechanism remains unclear. Here, we aimed to investigate by which GABA triggers weight loss improving beiging inguinal white adipose tissue (iWAT) and role gut microbiota in this process. The results showed that reduced body inflammation promoted expression thermogenic genes iWAT. 16S rRNA...
To investigate the association between albumin and preoperative deep vein thrombosis (DVT) in patients undergoing total joint arthroplasty (TJA). This study enrolled 2133 patients. We created receiver operator characteristic curve to determine cut-off values for (bromocresol green method) DVT TJA divided into groups based on value then assessed risk factors a multivariate logistic regression analysis. occurred 110 cases. The was 37.2 g/L area under 0.611. Multivariate analysis revealed that...
During a field survey of cultivated Morchella mushroom diseases, Diploöspora longispora and Paecilomyces penicillatus, causal agents pileus rot or white mould disease were detected, which resulted in up to 80% yield losses. Multi-locus phylogenic analysis revealed that the fungi affiliated distinct clade Hypocreales. We further constructed phylogenetic tree with broader sampling Hypocreales estimated divergence times. The D. P. penicillatus clades have diverged from Hypocreaceae around 129...
To investigate the association between platelet (PLT) indices and preoperative deep vein thrombosis (DVT) in elderly patients undergoing total joint arthroplasty (TJA). A of 1391 were enrolled. We created receiver operator characteristic (ROC) curve using ratio PLT to DVT before TJA, divided enrolled into groups based on cut-off value, then analyzed risk factors for TJA multivariate binary logistic regression analysis. Preoperative occurred 103 cases. Based ROC curve, we determined that...
Abstract The local field potential (LFP) is an extracellular electrical signal associated with neural ensemble input and dendritic signaling. Previous studies have linked gamma band oscillations of the LFP in cortical circuits to sensory stimuli encoding, attention, memory, perception. Inconsistent results regarding tuning for visual features were reported, but it remains unclear whether these discrepancies are due variations electrode properties. Specifically, surface area impedance...