A5036459456- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Listeria monocytogenes in Food Safety
- Nosocomial Infections in ICU
- Bacterial Identification and Susceptibility Testing
- Pneumonia and Respiratory Infections
- Salmonella and Campylobacter epidemiology
- Food Safety and Hygiene
- Microbial Inactivation Methods
- Emergency and Acute Care Studies
- Antibiotics Pharmacokinetics and Efficacy
- Microbial infections and disease research
- Sepsis Diagnosis and Treatment
- Otolaryngology and Infectious Diseases
- Rabies epidemiology and control
- Heme Oxygenase-1 and Carbon Monoxide
- Bacteriophages and microbial interactions
- Respiratory and Cough-Related Research
- Bacterial Infections and Vaccines
- Cerebrospinal fluid and hydrocephalus
- Infective Endocarditis Diagnosis and Management
- Respiratory viral infections research
- Urinary Tract Infections Management
- Legionella and Acanthamoeba research
- Tuberculosis Research and Epidemiology
City Clinical Hospital
2019-2024
Russian Medical Academy of Continuous Professional Education
2024
INTRODUCTION: Creation of protocols for effective empiric antimicrobial therapy is impossible without the analysis current antibiotic susceptibility data. OBJECTIVE: Analysis changes in etiological significance leading pathogens bacteremia ICU (intensive care unit) period from 2003 to 2021, and their sensitivity antibiotics; study types carbapenemases most relevant — Klebsiella pneumoniae Acinetobacter baumannii. MATERIALS AND METHODS: The included all microorganisms isolated blood patients...
Objective. To perform a comparative analysis of clinical and food isolates Listeria monocytogenes collected in the European part Russia 2018–2019. Materials Methods. We used multilocus sequencing (MLST), supplemented by virulence loci, including fragments internalin genes (MvLST, Multi-virulent-locus sequence typing), followed phylogenetic analysis. Results. The main diagnoses for were prenatal neonatal listeriosis meningitis. Clinical predominantly belonged to line II with predominance ST7,...
Журнал для непрерывного медицинского образования врачей Листериоз и пандемия COVID-19 1 Федеральное государственное бюджетное образовательное учреждение высшего «Московский государственный медико-стоматологический университет имени А.И.Евдокимова» Министерства здравоохранения, 127473, г.Москва, Российская Федерация 2 «Национальный исследовательский центр эпидемиологии микробиологии почетного академика Н.Ф.Гамалеи» 123098, 3 Институт общественного здоровья им.Ф.Ф.Эрисмана, автономное
The objective was to study the risk factors, outcomes of infections caused by colistin-resistant K. pneumonia (CRKP) and evaluate sensitivity these microorganisms antibacterial agents determine most adequate antibiotic therapy options. Materials methods . Klebsiella pneumoniae strains isolated in ICU an acute care hospital between October 2020 August 2022 were included study. Microorganisms identified using automatic analyzer PHOENIX. determination studied method serial micro-dilutions agar...
Nosocomial pneumonia is one of the most common healthcare-associated infections and frequent in intensive care unit (ICU) patients. The clinical economic consequences nosocomial are very significant, especially for ventilated In this article we present several observations that demonstrate difficulties antibacterial therapy ventilator-associated adults multidisciplinary hospitals Moscow, which due to both patient characteristics profile circulating pathogens.
Introduction. Listeriosis is a foodborne infection, especially dangerous for people in at-risk groups. Susceptibility to listeria infection determined by complex of reasons: environmental factors, host immune status, and pathogen virulence. The susceptibility listeriosis can also be aggravated previous infections, viral which demonstrate steadily increasing number identified pathogens.The aim our study was present molecular genetic characterization pathogens causing sporadic invasive...
Background . The difficulties of antibacterial therapy infections caused by carbapenemase-producing gram-negative bacteria are associated with limited options for adequate since, in addition to resistance carbapenems and other beta-lactams, these microorganisms often characterized classes antibiotics, including polymyxins. In vitro data support the idea combined use inhibitor-protected cephalosporins aztreonam treatment such infections. aim study was investigate effectiveness cefepime/sulbactam...
Background. Bacterial superinfection is one of the most common and potentially lethal complications in severely critically ill patients with COVID-19. Objectives. To determine colonisation time frame spectrum potential bacterial pathogens respiratory samples from severe critical COVID-19, using routine culture polymerase chain reaction (PCR) tests. Methods. A prospective observational study was conducted on aged ≥18 years confirmed COVID-19 who were admitted to or transferred intensive care...
Objective. To study spectrum of pathogens and the time to colonization respiratory samples in patients with severe critical COVID-19 as well analyze incidence nosocomial infections structure prescribed antibacterial drugs. Materials Methods. The prospective observational included aged 18 years older confirmed from December 2021 February 2022. During first 48 hours then every 2–3 days hospitalization, a sample was collected: sputum, tracheal aspirate (if intubated), bronchoalveolar lavage...
INTRODUCTION. Legionnaires' disease may be manifested by neurological symptoms along with lung damage. Cerebellar ataxia and dysarthria are rare extrapulmonary manifestations of legionellosis. These significantly reduce the quality life patients. AIM. To analyze literature data on legionellosis to present a clinical case manifestation symptoms. MATERIAL AND METHODS. We performed an analysis available literature. Twenty-four Russian international sources (PubMed databases) were evaluated,...
Objective. To study the etiology of community-acquired pneumonia (CAP) in adult hospitalized patients after COVID-19 pandemic. Materials and Methods. The prospective multicenter included 18 years older with confirmed diagnosis CAP admitted to 6 hospitals different regions Russia from July November 2023. Etiology was by respiratory samples (sputum, tracheal aspirate) culture, blood culture (severe cases), urinary antigen tests (Legionella pneumophila serogroup 1, Streptococcus pneumoniae)....
Objective. To determine the current state-of-art of acquired resistance to antimicrobial drugs among L. monocytogenes strains associated with listeriosis in humans and food contamination Moscow. Materials Methods. We used 39 isolated Moscow 2019–2021 from clinical material (n = 24) 15). Resistance 12 antibiotics first second lines defense was studied using disk-diffusion method. The parameters recommended for were interpret results; absence recommendations monocytogenes, criteria...
To evaluate the effectiveness of bacteriophages in complex surgical treatment septic diseases hand.We analyzed outcomes 111 patients with hand (septic arthritis, tendovaginitis, phlegmon). Surgical was finished by primary sutures and drainage. They were divided into two groups. Bacteriophages used main group. Other components identical. «Pyobacteriophage complex» injected drainage tubes during dressings. Effectiveness evaluated considering elimination process, bacterial flora healing wound....