A5040047077- Genomics and Rare Diseases
- Genetic Associations and Epidemiology
- Migration, Health and Trauma
- Forensic and Genetic Research
- Biotechnology and Related Fields
- Advanced Proteomics Techniques and Applications
- Global Health Workforce Issues
- Global Public Health Policies and Epidemiology
- Genetics, Bioinformatics, and Biomedical Research
- Metabolomics and Mass Spectrometry Studies
- Health disparities and outcomes
Zero to Three
2023
Rutgers, The State University of New Jersey
2021
African populations have been drastically underrepresented in genomics research, and failure to capture the genetic diversity across numerous ethnolinguistic groups (ELGs) found on continent has hindered equity of precision medicine initiatives globally. Here, we describe whole-genome sequencing 449 Nigerian individuals 47 unique self-reported ELGs. Population structure analysis reveals differentiation among our ELGs, consistent with previous findings. From 36 million SNPs insertions or...
Summary African populations have been drastically underrepresented in genomics research and failure to capture the genetic diversity across numerous ethnolinguistic groups (ELGs) found continent has hindered equity of precision medicine initiatives globally. Here, we describe whole-genome sequencing 449 Nigerian individuals 47 unique self-reported ELGs. Population structure analysis reveals differentiation amongst our ELGs, consistent with previous findings. From 36 million SNPs INDELs...
ABSTRACT Proteomic variation between individuals has immense potential for identifying novel drug targets and disease mechanisms. However, with high-throughput proteomic technologies still in their infancy, they have largely been applied large majority European ancestry cohorts (e.g. the UK Biobank). An open question is degree to which signatures seen other groups mirror those diverse populations, such as from Africa. Coupled genetic information, we can also gain a better understanding of...