A5041017853- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Radiomics and Machine Learning in Medical Imaging
- Cancer Genomics and Diagnostics
- Respiratory and Cough-Related Research
- Lung Cancer Treatments and Mutations
- Pulmonary Hypertension Research and Treatments
- Lung Cancer Research Studies
- Vascular Anomalies and Treatments
- Inhalation and Respiratory Drug Delivery
- Tracheal and airway disorders
- Neuroendocrine Tumor Research Advances
- Breastfeeding Practices and Influences
- Pediatric health and respiratory diseases
- Health Sciences Research and Education
- Health and Medical Research Impacts
- Sleep and related disorders
- Pleural and Pulmonary Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Ethics in Clinical Research
- Lung Cancer Diagnosis and Treatment
- Innovations in Medical Education
- Neonatal Respiratory Health Research
Uppsala University
2016-2024
Uppsala University Hospital
2017
Karolinska University Hospital
2011-2014
Progress in cancer biomarker discovery is dependent on access to high-quality biological materials and high-resolution clinical data from the same cases. To overcome current limitations, a systematic prospective longitudinal sampling of multidisciplinary data, blood tissue patients was therefore initiated 2010 by Uppsala Umeå Universities involving their corresponding University Hospitals, which are referral centers for one third Swedish population.Patients with selected types who treated at...
Lung volume reduction surgery can improve lung function and working capacity in severe heterogeneous emphysema. Endobronchial (ELVR) performed by one-way valves inserted via a flexible bronchoscope result moderate but significant improvement exercise tolerance, eliminating the surgical risks.Most studies of this method have excluded patients with α1-antitrypsin (AAT) deficiency, small series cases positive short-term outcome been reported. The sustainability results has questioned we here...
Identification of targetable EML4-ALK fusion proteins has revolutionized the treatment a minor subgroup non-small cell lung cancer (NSCLC) patients. Although fluorescence in situ hybridization (FISH) is regarded as gold standard for detection ALK rearrangements, immunohistochemistry (IHC) often used screening tool clinical practice. In order to unbiasedly analyze diagnostic impact such strategy, we compared IHC with FISH three large representative Swedish NSCLC cohorts incorporating...
Background: The risk of dying lung cancer is up to eightfold higher in patients with COPD than age- and gender-matched controls. aim this study was investigate the factors associated a large cohort from primary care centers. Methods: To analyze whether age, gender, socioeconomic factors, comorbidity, medication affect COPD, we used patients. Data medical records mandatory Swedish national registers were collected linked population-based, retrospective observational registry (NCT01146392)....
Background The term Asthma and COPD Overlap (ACO) describes a condition where asthma overlap. We aimed to investigate associations between ACO insomnia respiratory symptoms, the prevalence of characteristics subjects with in two Northern European population studies. Methods study comprised 25 429 aged ≥ 40 years who participated one general surveys. Both surveys included questions on asthma, COPD, sleep-related including difficulty initiating sleep, maintaining early-morning awakening,...
Medical treatment of pulmonary arterial hypertension (PAH) is increasingly common. Prostacyclins were introduced in the early 90s, and treprostinil one most frequently used drugs this class today, owing to its long half-life possibility administer molecule through several routes. Treprostinil considered a safe drug associated with significant improvement exercise capacity, especially patients idiopathic PAH (iPAH). Systemic sclerosis-associated (sc-PAH) correlates worse prognosis compared...
Chronic airflow limitation (CAL) is a hallmark of chronic obstructive pulmonary disease but also present in some patients with asthma. We investigated respiratory symptoms, sleep and health status participants without CAL particular emphasis on concurrent asthma using data from adult populations Iceland, Estonia Sweden within the Burden Obstructive Lung Disease study.
<b>Background:</b> The term Asthma and COPD Overlap Syndrome (ACOS) describes a condition where asthma overlap. We aimed to investigate associations between ACOS insomnia respiratory symptoms as well the prevalence characteristics of subjects with in two Northern European population studies. <b>Methods:</b> study comprised 25 429 aged ≥40 years that participated general surveys from Europe. Both included questions on asthma, COPD, sleep related including difficulty inducing sleep,...