- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Pharmacological Effects of Natural Compounds
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Metabolomics and Mass Spectrometry Studies
- Microbial Natural Products and Biosynthesis
- Chromatography in Natural Products
- Traditional Chinese Medicine Analysis
- Bioactive Compounds and Antitumor Agents
- Food Quality and Safety Studies
- Microbial Metabolites in Food Biotechnology
- Phytochemistry and Bioactive Compounds
- Plant biochemistry and biosynthesis
- Garlic and Onion Studies
- Natural Antidiabetic Agents Studies
- Biochemical Analysis and Sensing Techniques
- Sesquiterpenes and Asteraceae Studies
- Computational Drug Discovery Methods
- Surfactants and Colloidal Systems
- Plant chemical constituents analysis
- Vitamin C and Antioxidants Research
- Nigella sativa pharmacological applications
Medical University of Lublin
2016-2025
Medicina
2012-2023
University of the West Indies
2023
Institute of Medicinal Plant Development
2015-2016
Tannins are considered as valuable plant secondary metabolites providing many benefits for human health. In this review information was gathered about bioactivity in vitro and vivo, well conducted clinical trials. The literature research based on ScienceDirect, Scopus, Cochrane databases presents a wide range of tested activities tannins. described trials verify laboratory tests show the effective health taken from supplementation with
The Artemisia L. genus comprises over 500 species with important medicinal and economic attributes. Our study aimed at providing a comprehensive metabolite profiling bioactivity assessment of five collected from northeastern Romania (A. absinthium L., A. annua austriaca Jacq., pontica vulgaris L.). Liquid chromatography-tandem high-resolution mass spectrometry (LC-HRMS/MS) analysis methanol chloroform extracts obtained the roots aerial parts plants led to identification 15 phenolic acids...
This study focused on the biological evaluation and chemical characterization of
In the present study, biogenic selenium nanoparticles (SeNPs) have been prepared using Paenibacillus terreus and functionalized with nystatin (SeNP@PVP_Nystatin nanoconjugates) for inhibiting growth, morphogenesis, a biofilm in Candida albicans. Ultraviolet-visible spectroscopy analysis has shown characteristic absorption at 289, 303, 318 nm, X-ray diffraction peaks different 2θ values SeNPs. Electron microscopy that SeNPs are spherical shape size range of 220-240 nm. Fourier transform...
In this study, we aimed to describe the influence of natural terpenes on antimycobacterial activity first-line tuberculostatic drugs against isolated Mycobacterium tuberculosis.The used in study were R-limonene, S-limonene, myrcene, sabinene, α-pinene, and β-elemene. The values minimum inhibitory concentration (MIC) for these terpenes, as well combinations with antibiotics (ethambutol, isoniazid, rifampicin), determined using a tube log2 dilution method range 125-0.059 µg/mL.S-limonene had...
Background: On account of emergence multi- and extensively drug-resistant Mycobacterium tuberculosis (Mtb) strains, combinations drugs with natural compounds were tested to search for antibiotic activity enhancers. In this work we studied terpenes (α-pinene, bisabolol, β-elemene, (R)-limonene, (S)-limonene, myrcene, sabinene), which are the main constituents essential oil obtained from Mutellina purpurea L., a plant described antitubercular activity, investigate their interactions...
The purpose of the study was to evaluate antimycobacterial activity and possible action mode cinnamon bark essential oil its main constituent—cinnamaldehyde—against Mycobacterium tuberculosis ATCC 25177 strain. Cinnamaldehyde proved be bioactive compound responsible for mycobacterial growth inhibition bactericidal effects. cinnamaldehyde found comparable with that ethambutol, one first-line anti-TB antibiotics. selectivity index determined using cell culture studies in vitro showed a high...
The most commonly used plant source of β-elemene is Curcuma wenyujin Y. H. Chen & C. Ling (syn. aromatic Salisb.) with its content in supercritical CO₂ extract up to 27.83%. However, the other rich this compound Nigella damascena L. essential oil, which accounts for 47%. In work, effective protocol preparative isolation from a new source-N. oil-using high performance counter-current chromatography HPCCC was elaborated. Furthermore, since sesquiterpens are known as potent antimicrobials, need...
Mixture design is a statistical tool used to obtain the maximum desired effect using minimum number of experiments. The aim presented work was optimization composition mixture essential oils from basil, citronella, cedarwood and thyme simplex-lattice method. optimized parameter an antioxidant activity measured in DPPH assay expressed as effective concentration (EC50). test results showed interesting synergy between components oils. prepared binary quaternary mixtures were characterized by...