Roghayeh Mahmoudi

ORCID: 0000-0003-4780-130X
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About
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Research Areas
  • Laser Applications in Dentistry and Medicine
  • Circular RNAs in diseases
  • MicroRNA in disease regulation
  • Aquaculture Nutrition and Growth
  • Endodontics and Root Canal Treatments
  • Radioactive element chemistry and processing
  • Aquaculture disease management and microbiota
  • Phytase and its Applications
  • Selenium in Biological Systems
  • Apelin-related biomedical research
  • Cardiovascular Disease and Adiposity
  • Essential Oils and Antimicrobial Activity
  • Agricultural pest management studies
  • Cancer-related molecular mechanisms research
  • Effects of Radiation Exposure
  • Plant biochemistry and biosynthesis
  • Nerve injury and regeneration
  • Dental Trauma and Treatments
  • Food Chemistry and Fat Analysis
  • Spaceflight effects on biology
  • Antioxidant Activity and Oxidative Stress
  • Natural product bioactivities and synthesis
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • Tendon Structure and Treatment
  • Phytochemistry Medicinal Plant Applications

Hamedan University of Medical Sciences
2019-2023

Agricultural Biotechnology Research Institute of Iran
2021

Agricultural Research & Education Organization
2021

Background: Despite effective clinical responses, a large proportion of patients undergo resistance to radiotherapy. The low response rate current treatments in different stages colorectal cancer depends on the prominent role stem cells cancer. Objective: In present study, BMP-2 as an ionizing radiation-sensitive factor was investigated. Methods: A sphere formation assay used for enrichment HCT-116 (CSCs). effects combination therapy (BMP-2+ radiation) DNA damage (DDR), proliferation, and...

10.2174/1574888x18666230330085615 article EN Current Stem Cell Research & Therapy 2023-03-31

: This study aimed to evaluate the chemical composition and anticancer activity of Hamadan propolis essential oil methanolic extract on HCT116 cell line. The was evaluated by using MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) test colorectal analyzed gas chromatography-flame ionization detection (GC-FID) chromatography-mass spectrometry (GC-MS). total flavonoid phenolic content were assessed aluminum chloride colorimetric procedures Folin-Ciocalteu (F-C) assay,...

10.5812/jjcmb.115348 article EN Jentashapir Journal of Cellular and Molecular Biology 2021-06-28

Aim: The present study aimed to investigate photobiomodulation's (PBM) effect on inflamed dental pulp stem cells (IDPSCs) under different nutritional conditions. Methods: Cell proliferation and odontogenic differentiation were evaluated using the MTT assay real-time quantitative reverse transcription PCR, respectively after laser PBM of in 5 or 10% fetal bovine serum (FBS) culture Results: A significant positive irradiation cell both conditions 24 48 h was observed. DMP-1 gene expression...

10.2217/rme-2021-0056 article EN Regenerative Medicine 2021-12-21

: Chemoresistance is a severe drawback to the successful and effective treatment of colorectal cancer (CRC). Comprehensive molecular mechanisms chemoresistance facilitate development therapeutic strategies overcome in CRC. The dysregulation several non-coding RNAs was related Considering importance lncRNAs miRNAs as prognostic response biomarkers, this review focuses on role CRC chemoresistance. Non-coding have an essential tumor progression, metastasis, Thus, can be used respond biomarkers

10.5812/jjcmb.122461 article EN Jentashapir Journal of Cellular and Molecular Biology 2022-03-27

Abstract Background Salusins (α and β) have anti-atherogenic atherogenic effects. The aim of the study was to investigate effects salusins on expression level activity matrix metalloproteinase-2 (MMP-2) metalloproteinase-9 (MMP-9). Also we evaluated effect mRNA protein vascular endothelial growth factor-A (VEGF-A) cell adhesion molecule-1 (VCAM-1) in human umbilical vein cells (HUVECs). Methods Real-time PCR, Western blotting Zymograpgy techniques were used. Salusin-α suppressed Salusin-β...

10.21203/rs.3.rs-2440113/v1 preprint EN cc-by Research Square (Research Square) 2023-01-13
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