A5046826953- Advanced Materials and Mechanics
- Advanced Sensor and Energy Harvesting Materials
- Structural Analysis and Optimization
- Ultrasound Imaging and Elastography
- Elasticity and Material Modeling
- Ultrasonics and Acoustic Wave Propagation
- Metal and Thin Film Mechanics
- Force Microscopy Techniques and Applications
- Photoacoustic and Ultrasonic Imaging
- Cellular Mechanics and Interactions
- Adhesion, Friction, and Surface Interactions
- Liquid Crystal Research Advancements
- Ultrasound and Hyperthermia Applications
- Surface Modification and Superhydrophobicity
- Advanced Surface Polishing Techniques
- 3D Printing in Biomedical Research
- Cardiovascular Health and Disease Prevention
- Advanced Mathematical Physics Problems
- Non-Destructive Testing Techniques
- Architecture and Computational Design
- Stability and Controllability of Differential Equations
- Potassium and Related Disorders
- Fatigue and fracture mechanics
- Welding Techniques and Residual Stresses
- Liver Disease Diagnosis and Treatment
Tsinghua University
2015-2024
Handan College
2023-2024
Luohe Medical College
2023
Henan University Huaihe Hospital and Huaihe Clinical Institute
2020-2022
Soochow University
2021
Suzhou Research Institute
2021
Beihang University
2019
BeiGene (China)
2016-2018
Guilin University of Electronic Technology
2018
Tianjin University
2017
Wrinkling modes are determined for a two-layer system comprised of neo-Hookean film bonded to an infinitely deep substrate with the entire bilayer undergoing compression. The full range film/substrate modulus ratio is considered from limit traction-free homogeneous very stiff films on compliant substrates. role prestretch wherein unstretched prestretched wrinkling arising as stretch in relaxed. An exact bifurcation analysis reveals critical strain at onset wrinkling. Numerical simulations...
The three-dimensional patterns of surface wrinkling on a core-shell soft sphere are investigated through buckling and postbuckling analyses under differential tissue growth or shrinkage. With increasing deformation, the first exhibits buckyball-like pattern then undergoes wrinkle-to-fold transition into labyrinth folded patterns, in agreement with experimental observations. This involves dynamic movement, rotation, coalescence polygons formed during initial buckling.
The stability of the wrinkling mode experienced by a compressed half-space neo-Hookean material is investigated using analytical and numerical methods to study post-bifurcation behaviour periodic solutions. It shown that highly unstable owing nonlinear interaction among multiple modes associated with critical compressive state. Concomitantly, sensitive exceedingly small initial imperfections significantly reduce strain at which instability occurs. provides insight into connection between an...
Antibodies targeting PD-1 have been demonstrated durable anti-cancer activity in certain cancer types. However, the anti-PD-1 antibodies are less or not efficacious many situations, which might be attributed to co-expression of multiple inhibitory receptors presence immunosuppressive cells tumor microenvironment. Most used clinical studies IgG4 isotype with S228P mutation (IgG4S228P). The functional impact by interaction IgG4S228P antibody Fc gamma (FcγRs) is poorly understood. To assess...
In this paper we present analytical studies of three-dimensional viscous and inviscid simplified Bardina turbulence models with periodic boundary conditions.The global existence uniqueness weak solutions to the model has already been established by Layton Lewandowski.However, prove here well-posedness for weaker initial conditions.We also establish an upper bound dimension its attractor identify number degrees freedom model.We show that long-time dynamics solution is order (L/l d ) 12/5 ,...
We investigate the stiffening effect of graphene sheets dispersed in polymer nanocomposites using Mori–Tanaka micromechanics method. The effective elastic moduli sheet-reinforced composites are first predicted by assuming that all either aligned or randomly oriented matrix while maintaining their platelet-like shape. It is shown a very low content can considerably enhance stiffness composite. superiority as kind reinforcement further verified comparison with carbon nanotubes, another...
Abstract Periodic wrinkling across different scales has received considerable attention because it not only represents structure failure but also finds wide applications. How to prevent or create desired patterns is non‐trivial the dynamic evolution of wrinkles a highly nonlinear problem. Herein, we report simple yet powerful method dynamically tune and/or erase with visible light. The light‐induced photoisomerization azobenzene units in azopolymer films leads stress release and consequently...
Pressure sensors have a variety of applications including wearable devices and electronic skins. To satisfy the practical applications, pressure with high sensitivity, low detection limit, low-cost preparation are extremely needed. Herein, we fabricate highly sensitive based on hierarchically patterned polypyrrole (PPy) films, which composed three-scale nested surface wrinkling microstructures through simple process. Namely, double-scale wrinkles generated via in situ self-wrinkling during...
Abstract Pressure sensors have attracted tremendous attention because of their potential applications in the fields health monitoring, human–machine interfaces, artificial intelligence, and so on. Improving pressure‐sensing performances, especially sensitivity detection limit, is great importance to expand related applications, however it still an enormous challenge far. Herein, highly sensitive piezoresistive pressure are reported with novel light‐boosting sensing performances. Rose...
Podocytes are terminally differentiated epithelial cells lacking the ability to proliferate. The loss of podocytes is a hallmark progressive kidney diseases, including diabetic nephropathy (DN). Endoplasmic reticulum stress (ERS)-induced apoptosis involved in number pathological conditions, DN. aim present study was investigate whether high glucose environment induces through ERS. Differentiated mouse were divided into three groups: normal group (NG, 1 g/l D-glucose), (HG, 4.5 D-glucose) and...
Here we introduce a simple low-cost yet robust method to realize spontaneously wrinkled morphologies on spherical surfaces. It is based surface chemical oxidation of aqueous-phase-synthesized polydimethylsiloxane (PDMS) microspheres in the mixed H2SO4/HNO3/H2O solution. Consequently, curvature and overstress-sensitive wrinkles including dimples labyrinth patterns are successfully induced resulting oxidized PDMS microspheres. A power-law dependence wrinkling wavelength microsphere radius...
Constrained swelling or shrinkage of such soft materials as elastomers, polymeric hydrogels, and biological tissues can create various surface patterns through wrinkling subsequent morphological evolution. Here we study, both theoretically numerically, the swelling-driven pattern evolution cylindrical elastomers with core–shell structure. The results demonstrate that system may buckle into different morphologies under geometric material parameters. When shell core reaches a threshold, will...